William Reginold, Sarah Duff-Canning, Christopher Meaney, Melissa J Armstrong, Susan Fox, Brandon Rothberg, Cindy Zadikoff, Nancy Kennedy, David Gill, Paul Eslinger, Fred Marshall, Mark Mapstone, Kelvin L Chou, Carol Persad, Irene Litvan, Benjamin Mast, David Tang-Wai, Anthony E Lang, Connie Marras
BACKGROUND/AIMS: To assess the impact of mild cognitive impairment (MCI) or cognitive decline on health-related quality of life (HR-QOL) in Parkinson's disease (PD). METHODS: HR-QOL measured by the Parkinson Disease Quality of Life Questionnaire (PDQ-39), MCI according to Movement Disorder Society Task Force criteria and cognitive decline from premorbid baseline were assessed in non-demented PD patients at 6 movement disorder clinics. RESULTS: Among 137 patients, after adjusting for education, gender, disease duration, and Movement Disorder Society Unified Parkinson's Disease Rating Scale total score, MCI was associated with worse scores within the PDQ-39 dimension of communication (p = 0...
2013: Dementia and Geriatric Cognitive Disorders