Gail L Daumit, Faith B Dickerson, Nae-Yuh Wang, Arlene Dalcin, Gerald J Jerome, Cheryl A M Anderson, Deborah R Young, Kevin D Frick, Airong Yu, Joseph V Gennusa, Meghan Oefinger, Rosa M Crum, Jeanne Charleston, Sarah S Casagrande, Eliseo Guallar, Richard W Goldberg, Leslie M Campbell, Lawrence J Appel
BACKGROUND: Overweight and obesity are epidemic among persons with serious mental illness, yet weight-loss trials systematically exclude this vulnerable population. Lifestyle interventions require adaptation in this group because psychiatric symptoms and cognitive impairment are highly prevalent. Our objective was to determine the effectiveness of an 18-month tailored behavioral weight-loss intervention in adults with serious mental illness. METHODS: We recruited overweight or obese adults from 10 community psychiatric rehabilitation outpatient programs and randomly assigned them to an intervention or a control group...
April 25, 2013: New England Journal of Medicine