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2 papers 100 to 500 followers
By Sally Hodges Passionate about pancreatic cancer research. Experience in tissue collection, tumor staging, and all pancreas diseases.
Noboru Ideno, Takao Ohtsuka, Hiroshi Kono, Kenji Fujiwara, Yasunori Oda, Shinichi Aishima, Tetsuhide Ito, Kousei Ishigami, Shoji Tokunaga, Kenoki Ohuchida, Shunichi Takahata, Masafumi Nakamura, Kazuhiro Mizumoto, Masao Tanaka
OBJECTIVE: To identify a high-risk group of patients with pancreatic ductal adenocarcinoma (PDAC), independently arising in the pancreas with intraductal papillary mucinous neoplasm (IPMN), using histopathologic subtypes. BACKGROUND: Pathologic features of IPMN with distinct PDAC, including histopathologic subtypes of IPMN and PDAC phenotypes, have not been well characterized. Mucin expression patterns and the mutational status of GNAS and KRAS are useful to explore the relationship between these 2 lesion types...
July 2013: Annals of Surgery
Marius Distler, Stephan Kersting, Marco Niedergethmann, Daniela E Aust, Melanie Franz, Felix Rückert, Florian Ehehalt, Christian Pilarsky, Stefan Post, Hans-Detlev Saeger, Robert Grützmann
OBJECTIVE: To investigate different subtypes of intraductal papillary mucinous neoplasms (IPMNs) of the pancreas and their prognostic value. BACKGROUND: IPMNs of the pancreas are estimated to have a better prognosis than pancreatic ductal adenocarcinomas (PDACs). In addition to the different growth types (ie, main duct vs. branch duct types), the histological subtypes of IPMNs (ie, intestinal, pancreatobiliary, gastric, and oncocytic type) are prognostically relevant...
August 2013: Annals of Surgery
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