Alexander E Kostyunin, Arseniy E Yuzhalin, Maria A Rezvova, Evgeniy A Ovcharenko, Tatiana V Glushkova, Anton G Kutikhin
The implantation of bioprosthetic heart valves (BHVs) is increasingly becoming the treatment of choice in patients requiring heart valve replacement surgery. Unlike mechanical heart valves, BHVs are less thrombogenic and exhibit superior hemodynamic properties. However, BHVs are prone to structural valve degeneration (SVD), an unavoidable condition limiting graft durability. Mechanisms underlying SVD are incompletely understood, and early concepts suggesting the purely degenerative nature of this process are now considered oversimplified...
October 20, 2020: Journal of the American Heart Association