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Osteomyelitis and Cellulitis

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16 papers 500 to 1000 followers Pertaining mainly to foot and ankle. Let me know if there are any other parts that you think should be added subject wise.
By Alex McKanna Podiatry Resident @ Franciscan Alliance/MWU based in Dyer, IN USA
Efstathios Drampalos, Hasan Raza Mohammad, Chris Kosmidis, Moez Balal, Jason Wong, Anand Pillai
BACKGROUND: Chronic osteomyelitis necessities appropriate infected bone and soft tissue excision. The authors describe the Silo surgical technique for the treatment of calcaneal osteomyelitis using a new antibiotic-loaded absorbable calcium sulphate/hydroxyapatite biocomposite. METHODS: The Silo method involves debridement of the dead bone and local delivery of antibiotic in drilled tunnels using the biocomposite. It is combined with multiple sampling and culture-specific systemic antibiotic treatment guided by a multidisciplinary team...
March 2018: Foot
María Galindo, Isabel Mateo, José L Pablos
OBJECTIVE: Avascular necrosis of bone (AVN) and osteoarticular infection share similar risk factors in systemic lupus erythematosus (SLE) patients. However, their coincidental development in SLE has rarely been described. We describe four cases of AVN complicated by Staphylococcus aureus infection in SLE. METHODS: Patients were identified by retrospectively reviewing an SLE cohort followed between 1979 and 2003. A review of the literature from 1960 until 2003 was also done...
January 2005: Rheumatology International
Tammer Elmarsafi, Noah G Oliver, John S Steinberg, Karen K Evans, Christopher E Attinger, Paul J Kim
When osteomyelitis occurs in the infected foot, cement spacers have been used as a limb salvage tool. The aim of the present study was to assess the longevity and outcomes in high-risk, low-demand patients who have undergone resection of bone and subsequent placement of permanent antibiotic-eluting cement spacers in the foot. A retrospective review case series of 30 patients who had undergone placement of a permanent antibiotic-eluting cement spacer in the foot were evaluated for retention, spacer exchange, removal, amputation, and functional status...
March 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Andrea Donovan, Mark E Schweitzer
The clinical diagnosis of diabetes-related osteomyelitis relies on the identification and characterization of an associated foot ulcer, a method that is often unreliable. Magnetic resonance (MR) imaging is the modality of choice for imaging evaluation of pedal osteomyelitis. Because MR imaging allows the extent of osseous and soft-tissue infection to be mapped preoperatively, its use may limit the extent of resection. At MR imaging, the simplest method to determine whether osteomyelitis is present is to follow the path of an ulcer or sinus tract to the bone and evaluate the signal intensity of the bone marrow...
May 2010: Radiographics: a Review Publication of the Radiological Society of North America, Inc
Noah G Oliver, John S Steinberg, Kelly Powers, Karen K Evans, Paul J Kim, Christopher E Attinger
Partial calcanectomy (PC) is an established limb salvage procedure for treatment of deep heel ulceration with concomitant calcaneal osteomyelitis. The purpose of this study is to determine if a relationship exists between the amount of calcaneus removed during PC and the resulting lower extremity function and limb salvage outcomes. Consecutive PC patients were retrospectively divided into two cohorts defined by the amount of calcaneus resected before wound closure: patients in cohort 1 retained = 50% of calcaneus, while patients in cohort 2 underwent resection of >50% of the calcaneus...
2015: Journal of Diabetes Research
Daniel Patton, Nathan Kiewiet, Michael Brage
BACKGROUND: Infections in total ankle arthroplasty are a serious complication, about which there is little information in the current literature. METHODS: This is a retrospective review of infected total ankle arthroplasty at one institution from 1995 to 2012. Risk factors were compared between patients with infected total ankle arthroplasty and age- and sex-matched patients who did not have infection (control patients) within the same time period. RESULTS: 966 patients with total ankle arthroplasty were reviewed, and 29 cases of infected total ankle arthroplasty (3...
June 2015: Foot & Ankle International
Troy J Boffeli, Brett J Waverly
Traditional incision techniques for midfoot amputation might not provide immediate soft tissue coverage of the underlying metatarsal and tarsal bones in the presence of a large plantar soft tissue defect. Patients undergoing transmetatarsal and Lisfranc amputation frequently have compromised plantar tissue in association with neuropathic ulcers, forefoot gangrene, and infection, necessitating wide resection as a part of the amputation procedure. Open amputation will routinely be performed under these circumstances, although secondary healing could be compromised owing to residual bone exposure...
March 2016: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
Jeffrey C Karr, Joseph Lauretta
Background: Regarding antibiotic-loaded cements, there is an abundant amount of literature regarding the antibacterial in vitro inhibitory and clinical applications for the treatment of osteomyelitis. The opposite can be said about literature regarding in vitro antifungal-loaded cement drug delivery for the treatment of fungal osteomyelitis. Methods: Aspergillus fumigatus and Candida (ATCC 10231; ATCC, Manassas, Virginia) were plated on antibiotic/antifungal-free plates. Voriconazole- and amphotericin B-impregnated calcium sulfate and hydroxyapatite (HA) disks, calcium sulfate + HA control disks, and control polymethylmethacrylate disks were laid separately onto plates separately inoculated with Aspergillus and Candida spp...
February 4, 2015: Journal of the American Podiatric Medical Association
Wystan Chevannes, Arman Memarzadeh, Chandra Pasapula
Tuberculosis is one of the leading causes of death worldwide amongst curable diseases. It is estimated that one-third of the world's population has been diagnosed with tuberculosis infection [1]. The prevalence is on the rise with an estimated 9.4 million new cases per year worldwide [1]. Tuberculosis most commonly presents with pulmonary involvement. However, approximately 23-30% of patients found to be infected with tuberculosis have extrapulmonary symptoms [2]. Of those, only 1-3% have been found to have osseous disease...
March 2015: Foot
Miki Fujii, Hiroto Terashi, Shinya Tahara
BACKGROUND: The clinical diagnosis of osteomyelitis is difficult because of neuropathy, vascular disease, and immunodeficiency; also, with no established consensus on the diagnosis of foot osteomyelitis, the reported efficacy of magnetic resonance imaging (MRI) in detecting osteomyelitis and distinguishing it from reactive bone marrow edema is unclear. Herein, we describe a retrospective study on the efficacy of MRI for decision-making accuracy in diagnosing osteomyelitis in diabetic foot ulcers...
January 2014: Journal of the American Podiatric Medical Association
Polly J Ferguson, Monica Sandu
Chronic recurrent multifocal osteomyelitis (CRMO) is an inflammatory disorder that primarily affects children. Its hallmark is recurring episodes of sterile osteomyelitis. The clinical presentation is insidious onset of bone pain with or without fever. Laboratory studies typically reveal nonspecific evidence of inflammation. Radiologic imaging and histologic appearance resemble those of infectious osteomyelitis. There is a strong association with inflammatory disorders of the skin and intestinal tract in affected individuals and their close relatives, suggesting a shared pathophysiology and supporting a genetic component to disease susceptibility...
April 2012: Current Rheumatology Reports
Sabitha Rajan
Skin and soft-tissue infections (SSTIs) are a common presenting problem in both inpatients and outpatients. SSTIs have been broadly classified as complicated or uncomplicated, but specific disease processes and patient characteristics are important in guiding clinical management. Early recognition of the extent of infection, close follow-up, and familiarity with local antibiotic susceptibility data are critical to successful treatment.
January 2012: Cleveland Clinic Journal of Medicine
Guilermo E Umpierez
Many patients admitted to the hospital have diabetes mellitus-diagnosed or undiagnosed-and others develop hyperglycemia from the stress of hospitalization. This paper discusses the prevalence, outcomes, and evidence for best management of hyperglycemia and diabetes in hospitalized patients outside the critical care setting.
June 2011: Cleveland Clinic Journal of Medicine
Paul W Johnson, Mark S Collins, Doris E Wenger
OBJECTIVE: The purpose of this study was to evaluate the diagnostic utility of specific characteristics on T1-weighted MR images in the diagnosis of pedal osteomyelitis. MATERIALS AND METHODS: The study included all adult patients who underwent MRI of the foot for evaluation of suspected osteomyelitis over an 11-month period. Images were retrospectively reviewed for specific criteria on T1-weighted images, including signal intensity of affected bone marrow (normal or decreased), distribution of abnormal signal intensity (subcortical or medullary), and pattern of involvement (hazy reticulated or confluent)...
January 2009: AJR. American Journal of Roentgenology
J-L Richard, A Sotto, N Jourdan, C Combescure, D Vannereau, M Rodier, J-P Lavigne
AIM: To determine the risk factors for acquiring multidrug-resistant organisms (MDRO) and their impact on outcome in infected diabetic foot ulcers. METHODS: Patients hospitalized in our diabetic foot unit for an episode of infected foot ulcer were prospectively included. Diagnosis of infection was based on clinical findings using the International Working Group on the Diabetic Foot-Infectious Diseases Society of America (IWGDF-ISDA) system, and wound specimens were obtained for bacterial cultures...
September 2008: Diabetes & Metabolism
George Cierny, Jon T Mader, Johan J Penninck
No abstract text is available yet for this article.
September 2003: Clinical Orthopaedics and related Research
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