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CTE

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155 papers 25 to 100 followers
By David Rhine MD FRCPC. Emergency medicine. Special interest in concussion management.
https://read.qxmd.com/read/30844072/no-linear-association-between-number-of-concussions-or-years-played-and-cognitive-outcomes-in-retired-nfl-players
#1
Lindy Fields, Nyaz Didehbani, John Hart, C Munro Cullum
OBJECTIVE: The aim of the current study is to examine whether concussion history and years played are linearly associated with cognitive outcomes in retired National Football League (NFL) players. METHOD: Thirty-five retired NFL players over the age of 50 who had sustained at least one concussion completed a clinical interview and brief neuropsychological battery. Correlational analyses were conducted between exposure variables [number of total concussions, concussions with loss of consciousness (LOC), and years played] and cognitive performance as characterized by cognitive composite scores based on performance on neuropsychological measures (attention/processing speed, language, memory, and overall composite scores)...
March 7, 2019: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://read.qxmd.com/read/30748078/lithium-treatment-for-chronic-traumatic-encephalopathy-a-proposal
#2
EDITORIAL
S Nassir Ghaemi, Sivan Mauer, Bennet I Omalu
Chronic traumatic encephalopathy (CTE) is a diagnosis recently discovered and described in the context of American football. It is a a neurodegenerative disease that is a consequence of repetitive brain injury such as concussion. Such injury most notably occurs in physically violent sports but can also occur in other settings, such as during military duty, where explosive blasts can cause subconcussive impacts to the head. The main clinical features of CTE involve three aspects: mood/impulsivity, suicide, and dementia...
February 12, 2019: Bipolar Disorders
https://read.qxmd.com/read/30730386/american-medical-society-for-sports-medicine-position-statement-on-concussion-in-sport
#3
Kimberly G Harmon, James R Clugston, Katherine Dec, Brian Hainline, Stanley A Herring, Shawn Kane, Anthony P Kontos, John J Leddy, Michael A McCrea, Sourav K Poddar, Margot Putukian, Julie C Wilson, William O Roberts
Sport-related concussion (SRC) is a common injury in recreational and organized sport. Over the past 30 years, there has been significant progress in our scientific understanding of SRC, which in turn has driven the development of clinical guidelines for diagnosis, assessment, and management of SRC. In addition to a growing need for knowledgeable health care professionals to provide evidence-based care for athletes with SRC, media attention and legislation have created awareness and, in some cases, fear about many issues and unknowns surrounding SRC...
March 2019: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://read.qxmd.com/read/30696951/concussion-and-risk-of-suicide-who-when-and-under-what-circumstances
#4
Lisa A Brenner, Nazanin H Bahraini
No abstract text is available yet for this article.
January 29, 2019: Nature Reviews. Neurology
https://read.qxmd.com/read/30649104/effects-of-repetitive-head-impacts-on-a-concussion-assessment-battery
#5
Jaclyn B Caccese, Chelsea Best, Lindsey C Lamond, Melissa DiFabio, Thomas W Kaminski, Dan Watson, Nancy Getchell, Thomas A Buckley
PURPOSE: The purpose of this study was to determine the relationship between repetitive head impacts (RHI) and clinical concussion assessments across a season among collegiate football (FB) and women's soccer (WSOC) players. METHODS: Fifteen male FB and 23 WSOC players participated in this study. Participants were included if they were medically cleared for unrestricted athletic participation. Participants were tested in a university athletic training room on two occasions: pre-season (PRE) and post-season (POST)...
January 14, 2019: Medicine and Science in Sports and Exercise
https://read.qxmd.com/read/30419085/association-of-concussion-with-the-risk-of-suicide-a-systematic-review-and-meta-analysis
#6
Michael Fralick, Eric Sy, Adiba Hassan, Matthew J Burke, Elizabeth Mostofsky, Todd Karsies
Importance: Concussion is the most common form of traumatic brain injury (TBI). While most patients fully recover within 1 week of injury, a subset of patients might be at a higher risk of suicide. Objective: To assess the risk of suicide after concussion. Data Sources: We performed a systematic search of Medline (PubMed), Embase, PsycINFO, and Published International Literature on Traumatic Stress (PILOTS) from 1963 to May 1, 2017. We also searched Google Scholar and conference proceedings and contacted experts in the field to seek additional studies...
November 12, 2018: JAMA Neurology
https://read.qxmd.com/read/30419107/on-the-link-between-concussions-and-suicide
#7
Donald A Redelmeier, Junaid A Bhatti
No abstract text is available yet for this article.
November 12, 2018: JAMA Neurology
https://read.qxmd.com/read/30391039/mild-traumatic-brain-injury-is-dti-ready-for-the-courtroom
#8
REVIEW
Martha E Shenton, Bruce H Price, Laura Levin, Judith G Edersheim
Important advances in neuroscience and neuroimaging have revolutionized our understanding of the human brain. Many of these advances provide new evidence regarding compensable injuries that have been used to support changes in legal policy. For example, we now know that regions of the brain involved in decision making continue to develop into the mid-20s, and this information weighs heavily in determining that execution or automatic sentence of life without the possibility of parole for someone younger than 18 years old, at the time of the crime, violates the 8th Amendment prohibition against "cruel and unusual punishment...
November 2018: International Journal of Law and Psychiatry
https://read.qxmd.com/read/30120477/association-between-traumatic-brain-injury-and-risk-of-suicide
#9
Trine Madsen, Annette Erlangsen, Sonja Orlovska, Ramy Mofaddy, Merete Nordentoft, Michael E Benros
Importance: Traumatic brain injuries (TBIs) can have serious long-term consequences, including psychiatric disorders. However, few studies have assessed the association between TBI and risk of suicide. Objective: To examine the association between TBI and subsequent suicide. Design, Setting, and Participants: Retrospective cohort study using nationwide registers covering 7 418 391 individuals (≥10 years) living in Denmark (1980-2014) with 164 265 624 person-years' follow-up; 567 823 (7...
August 14, 2018: JAMA: the Journal of the American Medical Association
https://read.qxmd.com/read/30080799/multimodal-imaging-of-retired-professional-contact-sport-athletes-does-not-provide-evidence-of-structural-and-functional-brain-damage
#10
Robert Zivadinov, Paul Polak, Ferdinand Schweser, Niels Bergsland, Jesper Hagemeier, Michael G Dwyer, Deepa P Ramasamy, John G Baker, John J Leddy, Barry S Willer
BACKGROUND: Long-term consequences of playing professional football and hockey on brain function and structural neuronal integrity are unknown. OBJECTIVES: To investigate multimodal metabolic and structural brain magnetic resonance imaging (MRI) differences in retired professional contact sport athletes compared with noncontact sport athletes. METHODS: Twenty-one male contact sport athletes and 21 age-matched noncontact sport athletes were scanned on a 3 tesla (3T) MRI using a multimodal imaging approach...
September 2018: Journal of Head Trauma Rehabilitation
https://read.qxmd.com/read/30080797/evaluation-of-executive-function-and-mental-health-in-retired-contact-sport-athletes
#11
Barry S Willer, Michael R Tiso, Mohammad N Haider, Andrea L Hinds, John G Baker, Jeffery C Miecznikowski, John J Leddy
OBJECTIVE: To compare retired professional contact sport athletes with age-matched noncontact sport athletes on measures of executive function and mental health. SETTING: The University Concussion Management Clinic. PARTICIPANTS: Twenty-one retired National Football League (NFL) and National Hockey League (NHL) players (mean age 56 years) and 21 age-matched noncontact sport athlete controls. DESIGNS: Case control. MAIN MEASURE: The self- and informant-reported Behavior Rating Inventory of Executive Function-Adult form (BRIEF-A); Wisconsin Card Sorting Test; Delis-Kaplan Executive Function System; Trail Making Part A and B; Wechsler Adult Intelligence Scale; Neuropsychological Assessment Battery; List Learning; Controlled Oral Word Association Test; Beck Depression Inventory; Beck Anxiety Inventory; and Personality Inventory of the DSM-5...
September 2018: Journal of Head Trauma Rehabilitation
https://read.qxmd.com/read/30080796/a-preliminary-study-of-early-onset-dementia-of-former-professional-football-and-hockey-players
#12
Barry S Willer, Robert Zivadinov, Mohammad N Haider, Jeffrey C Miecznikowski, John J Leddy
OBJECTIVE: To provide an overview of 3 studies of the same population of retired professional contact sport athletes compared with age-matched noncontact sport athlete controls on cognition, executive function, behavior, and advanced brain imaging. SETTING: University Concussion Management Clinic. PARTICIPANTS: Twenty-two retired professional hockey and football athletes (average age 56 years) and 21 age-matched noncontact sport athlete controls...
September 2018: Journal of Head Trauma Rehabilitation
https://read.qxmd.com/read/29987335/building-good-policy-from-good-science-the-case-for-concussion-and-chronic-traumatic-encephalopathy
#13
Christopher C Giza, William Stewart, Mayumi L Prins
No abstract text is available yet for this article.
September 1, 2018: JAMA Pediatrics
https://read.qxmd.com/read/29665736/fear-avoidance-and-clinical-outcomes-from-mild-traumatic-brain-injury
#14
Noah D Silverberg, William J Panenka, Grant L Iverson
Characterizing psychological factors that contribute to persistent symptoms after mild traumatic brain injury (MTBI) can inform early intervention. To determine whether fear avoidance, a known risk factor for chronic disability after musculoskeletal injury, is associated with worse clinical outcomes from MTBI, adults were recruited from four outpatient MTBI clinics and assessed at their first clinic visit (mean = 2.7, standard deviation = 1.5 weeks post-injury) and again four to five months later. Of 273 patients screened, 102 completed the initial assessment, and 87 returned for the outcome assessment...
August 15, 2018: Journal of Neurotrauma
https://read.qxmd.com/read/29666148/single-mild-concussion-increases-risk-of-parkinson-s-disease-study-suggests
#15
Ingrid Torjesen
No abstract text is available yet for this article.
April 17, 2018: BMJ: British Medical Journal
https://read.qxmd.com/read/29526776/sub-concussive-trauma-acute-concussion-and-history-of-multiple-concussions-effects-on-quiet-stance-postural-control-stability
#16
J K Dierijck, A D Wright, J D Smirl, K Bryk, P van Donkelaar
Although balance control has been studied extensively following acute concussion, little is known regarding repetitive sub-concussive head impacts or chronic exposure to multiple concussive events. Quiet stance postural control was characterized in contact sport athletes at pre-season (n = 135) and post-season (n = 48) to evaluate the effects of subconcussive trauma to the head. To determine the impact of acute concussion on postural control, athletes diagnosed with a concussion during the season (n = 12) were tested at 72-h, 2-weeks, and 1-month post-injury...
March 8, 2018: International Journal of Psychophysiology
https://read.qxmd.com/read/29521703/athletic-suicide-separating-fact-from-fiction-and-navigating-the-challenging-road-ahead
#17
Ashwin L Rao
No abstract text is available yet for this article.
March 2018: Current Sports Medicine Reports
https://read.qxmd.com/read/29402530/subconcussive-head-impacts-in-sport-a-systematic-review-of-the-evidence
#18
Lynda Mainwaring, Kaleigh M Ferdinand Pennock, Sandhya Mylabathula, Benjamin Z Alavie
PURPOSE: To identify and evaluate the evidence that examines subconcussive impacts in sport-specific settings, and address two objectives: a) to determine how 'subconcussion' is characterized in the current literature, and b) to identify directions for future research. RESEARCH DESIGN: Systematic review. METHODS AND PROCEDURES: CINAHL, EMBASE, MedLine, PsycINFO, SportDiscus, and Web of Science were searched for articles that sought to assess subconcussive impacts or outcomes related to non-concussive head impact exposure...
February 2, 2018: International Journal of Psychophysiology
https://read.qxmd.com/read/29385179/population-based-cohort-study-of-the-impacts-of-mild-traumatic-brain-injury-in-adults-four-years-post-injury
#19
Alice Theadom, Nicola Starkey, Suzanne Barker-Collo, Kelly Jones, Shanthi Ameratunga, Valery Feigin
There is increasing evidence that some people can experience persistent symptoms for up to a year following mild TBI. However, few longitudinal studies of mild TBI exist and the longer-term impact remains unclear. The purpose of this study is to determine if there are long-term effects of mild traumatic brain injury (TBI) four-years later. Adults (aged ≥16 years) identified as part of a TBI incidence study who experienced a mild-TBI four-years ago (N = 232) were compared to age-sex matched controls (N = 232)...
2018: PloS One
https://read.qxmd.com/read/29388850/neurophysiological-and-cognitive-impairment-following-repeated-sports-concussion-injuries-in-retired-professional-rugby-league-players
#20
Alan J Pearce, Billymo Rist, Clare L Fraser, Adrian Cohen, Jerome J Maller
BACKGROUND: Concussion is regarded as a common injury in rugby league, however no studies have explored the long-term neurophysiological and cognitive effects of repeated concussion injuries in this sport. METHODS: Former professional rugby athletes (n = 25) were compared to 25 age-matched participants with no history of a concussion. All participants completed standardised motor dexterity, reaction time, and cognitive tasks for working memory, associative learning and rule acquisition and reversal...
2018: Brain Injury: [BI]
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