Frank M Sacks, Vincent J Carey, Cheryl A M Anderson, Edgar R Miller, Trisha Copeland, Jeanne Charleston, Benjamin J Harshfield, Nancy Laranjo, Phyllis McCarron, Janis Swain, Karen White, Karen Yee, Lawrence J Appel
IMPORTANCE: Foods that have similar carbohydrate content can differ in the amount they raise blood glucose. The effects of this property, called the glycemic index, on risk factors for cardiovascular disease and diabetes are not well understood. OBJECTIVE: To determine the effect of glycemic index and amount of total dietary carbohydrate on risk factors for cardiovascular disease and diabetes. DESIGN, SETTING, AND PARTICIPANTS: Randomized crossover-controlled feeding trial conducted in research units in academic medical centers, in which 163 overweight adults (systolic blood pressure, 120-159 mm Hg) were given 4 complete diets that contained all of their meals, snacks, and calorie-containing beverages, each for 5 weeks, and completed at least 2 study diets...
December 17, 2014: JAMA