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IUI Infertility

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5 papers 0 to 25 followers Intrauterine insemination
Ben Cohlen, Aartjan Bijkerk, Sheryl Van der Poel, Willem Ombelet
BACKGROUND: IUI with or without ovarian stimulation (OS) has become a first-line treatment option for many infertile couples, worldwide. The appropriate treatment modality for couples and their clinical management through IUI or IUI/OS cycles must consider maternal and perinatal outcomes, most notably the clinical complication of higher-order multiple pregnancies associated with IUI-OS. With a current global emphasis to continue to decrease maternal and perinatal mortality and morbidity, the World Health Organization (WHO) had established a multi-year project to review the evidence for the establishment of normative guidance for the implementation of IUI as a treatment to address fertility problems, and to consider its cost-effectiveness for lower resource settings...
May 1, 2018: Human Reproduction Update
Raïssa I Tjon-Kon-Fat, Parvin Tajik, Inge M Custers, Patrick M M Bossuyt, Fulco van der Veen, Madelon van Wely, Ben W Mol, Mohammad H Zafarmand
OBJECTIVE: Available treatment options in couples with unexplained or mild male subfertility are intrauterine insemination with controlled ovarian hyperstimulation (IUI-COH) and in vitro fertilisation (IVF). IUI-COH is a less invasive treatment that is often used before proceeding with IVF. Yet as the IVF success rates might be higher and time to pregnancy shorter, expedited access to IVF might be the preferred option. To identify couples that could benefit from immediate IVF over IUI-COH, we assessed whether female age, duration of subfertility or prewash total motile count (TMC) can help to identify couples that would benefit from IVF over IUI-COH...
July 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
Ashraf Moini, Firoozeh Ahmadi, Nadia Jahangiri, Jila Ahmadi, Mohammad Reza Akhoond
OBJECTIVE: To investigate the effects of low-dose ethinyl estradiol (EE) on the clinical pregnancy rate among women with polycystic ovary syndrome (PCOS) undergoing ovulation induction with clomiphene citrate (CC). METHODS: Between March 12, 2011, and February 10, 2013, a randomized, double-blind, placebo-controlled trial was conducted at the Royan Institute Research Center, Tehran, Iran, among women with PCOS who were aged 25-30 years, were undergoing their first intrauterine insemination cycle, and had a history (≥2 years) of infertility, oligomenorrhea, or amenorrhea...
November 2015: International Journal of Gynaecology and Obstetrics
Antonio Requena, María Cruz, Alberto Pacheco, Juan Antonio García-Velasco
OBJECTIVE: To determine the relationship between serum P levels on the day of hCG administration and ongoing pregnancy rates. DESIGN: Retrospective study. SETTING: University-affiliated private IVF. PATIENT(S): A total of 2,458 couples undergoing IUI. INTERVENTION(S): Ovarian stimulation with human recombinant FSH. MAIN OUTCOME MEASURE(S): Ongoing pregnancy and miscarriage rates...
October 2015: Fertility and Sterility
Astrid E P Cantineau, Mirjam J Janssen, Ben J Cohlen, Thomas Allersma
BACKGROUND: In many countries intrauterine insemination (IUI) is the treatment of first choice for a subfertile couple when the infertility work up reveals an ovulatory cycle, at least one open Fallopian tube and sufficient spermatozoa. The final goal of this treatment is to achieve a pregnancy and deliver a healthy (singleton) live birth. The probability of conceiving with IUI depends on various factors including age of the couple, type of subfertility, ovarian stimulation and the timing of insemination...
December 21, 2014: Cochrane Database of Systematic Reviews
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