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Bone stim

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6 papers 100 to 500 followers Papers on the efficacy and uses of bone healing stimulators
By Alex McKanna Podiatry Resident @ Franciscan Alliance/MWU based in Dyer, IN USA
Waldemar Hoffmann, Sandra Feliciano, Ivan Martin, Michael de Wild, David Wendt
Secondary bone fracture healing is a physiological process that leads to functional tissue regeneration via endochondral bone formation. In vivo studies have demonstrated that early mobilization and the application of mechanical loads enhances the process of fracture healing. However, the influence of specific mechanical stimuli and particular effects during specific phases of fracture healing remain to be elucidated. In this work, we have developed and provided proof-of-concept of an in vitro human organotypic model of physiological loading of a cartilage callus, based on a novel perfused compression bioreactor (PCB) system...
2015: Frontiers in Bioengineering and Biotechnology
Jeremy J Cook, N Jake Summers, Emily A Cook
Electromagnetic fields and their uses in bone healing have been fairly well studied, with most results showing improvement in healing of both bone and cartilage. Most supportive data are found in relation to the spine, femur, and tibia, but there is increasing evidence for its use in the foot and ankle for treatment of nonunions and as an adjunctive device in arthrodeses, particularly in high-risk populations. There are varying data and a significant variety of quality in the current research and publications concerning the use of electrical bone stimulation in the treatment of the foot and ankle...
January 2015: Clinics in Podiatric Medicine and Surgery
Javier La Fontaine, Nathan A Hunt, Stacey Curry, Tyler Kearney, Daniel Jupiter, Naohiro Shibuya, Lawrence A Lavery
BACKGROUND: Persons with diabetes have a higher incidence of fractures compared with persons without diabetes. However, there is little published information concerning the deleterious effect of late-stage diabetes on fracture healing. There are no studies using animal models that evaluate the effect of advanced diabetes on fracture healing. The purpose of our study was to evaluate cytokine expression, specifically macrophage inflammatory protein 1 (MIP-1) and vascular endothelial growth factor, in fracture healing in a type 2 diabetes rat model...
September 2014: Journal of the American Podiatric Medical Association
P A Nolte, A van der Krans, P Patka, I M Janssen, J P Ryaby, G H Albers
BACKGROUND: Low-intensity ultrasound has demonstrated an acceleration of bone healing and more profound callus formation in animal and human clinical experiments. In this study, the effect of pulsed, low-intensity ultrasound was determined in established nonunion cases. METHODS: The enrolled cases were reviewed for the time from their last surgical procedure and evidence of no healing or progression of healing during the 3 or more months before the start of low-intensity ultrasound therapy to determine whether the cases were established nonunions...
October 2001: Journal of Trauma
T K Kristiansen, J P Ryaby, J McCabe, J J Frey, L R Roe
A multicenter, prospective, randomized, double-blind, placebo-controlled clinical trial was conducted to test the efficacy of a specifically programmed, low-intensity, non-thermal, pulsed ultrasound medical device for shortening the time to radiographic healing of dorsally angulated fractures (negative volar angulation) of the distal aspect of the radius that had been treated with manipulation and a cast. Sixty patients (sixty-one fractures) were enrolled in the study within seven days after the fracture. The patients used either an active ultrasound device (thirty fractures) or a placebo device (thirty-one fractures) daily for twenty minutes at home for ten weeks...
July 1997: Journal of Bone and Joint Surgery. American Volume
J D Heckman, J P Ryaby, J McCabe, J J Frey, R F Kilcoyne
Sixty-seven closed or grade-I open fractures of the tibial shaft were examined in a prospective, randomized, double-blind evaluation of use of a new ultrasound stimulating device as an adjunct to conventional treatment with a cast. Thirty-three fractures were treated with the active device and thirty-four, with a placebo control device. At the end of the treatment, there was a statistically significant decrease in the time to clinical healing (86 +/- 5.8 days in the active-treatment group compared with 114 +/- 10...
January 1994: Journal of Bone and Joint Surgery. American Volume
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