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5 papers 500 to 1000 followers
By Faye Kehler Family Physician and GP Anesthetist since 1987 interested in all aspects of Medicine
Karin J Neufeld, Jirong Yue, Thomas N Robinson, Sharon K Inouye, Dale M Needham
OBJECTIVES: To evaluate the effectiveness of antipsychotic medications in preventing and treating delirium. DESIGN: Systematic review and meta-analysis. SETTING: PubMed, EMBASE, CINAHL, and databases were searched from January 1, 1988, to November 26, 2013. PARTICIPANTS: Adult surgical and medical inpatients. INTERVENTION: Antipsychotic administration for delirium prevention or treatment in randomized controlled trials or cohort studies...
April 2016: Journal of the American Geriatrics Society
Sharon K Inouye, Cyrus M Kosar, Douglas Tommet, Eva M Schmitt, Margaret R Puelle, Jane S Saczynski, Edward R Marcantonio, Richard N Jones
BACKGROUND: Quantifying the severity of delirium is essential to advancing clinical care by improved understanding of delirium effect, prognosis, pathophysiology, and response to treatment. OBJECTIVE: To develop and validate a new delirium severity measure (CAM-S) based on the Confusion Assessment Method. DESIGN: Validation analysis in 2 independent cohorts. SETTING: Three academic medical centers. PATIENTS: The first cohort included 300 patients aged 70 years or older scheduled for major surgery...
April 15, 2014: Annals of Internal Medicine
Adela Mitasova, Milena Kostalova, Josef Bednarik, Radka Michalcakova, Tomas Kasparek, Petra Balabanova, Ladislav Dusek, Stanislav Vohanka, E Wesley Ely
OBJECTIVE: To describe the epidemiology and time spectrum of delirium using Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition criteria and to validate a tool for delirium assessment in patients in the acute poststroke period. DESIGN: A prospective observational cohort study. SETTING: The stroke unit of a university hospital. PATIENTS: A consecutive series of 129 patients with stroke (with infarction or intracerebral hemorrhage, 57 women and 72 men; mean age, 72...
February 2012: Critical Care Medicine
Edward R Marcantonio, Long H Ngo, Margaret O'Connor, Richard N Jones, Paul K Crane, Eran D Metzger, Sharon K Inouye
BACKGROUND: Delirium is common, leads to other adverse outcomes, and is costly. However, it often remains unrecognized in most clinical settings. The Confusion Assessment Method (CAM) is the most widely used diagnostic algorithm, and operationalizing its features would be a substantial advance for clinical care. OBJECTIVE: To derive the 3D-CAM, a new 3-minute diagnostic assessment for CAM-defined delirium, and validate it against a clinical reference standard. DESIGN: Derivation and validation study...
October 21, 2014: Annals of Internal Medicine
Jayna M Holroyd-Leduc, Farah Khandwala, Kaycee M Sink
No abstract text is available yet for this article.
March 23, 2010: CMAJ: Canadian Medical Association Journal, Journal de L'Association Medicale Canadienne
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