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Periferal vascular disease

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6 papers 25 to 100 followers
By Faye Kehler Family Physician and GP Anesthetist since 1987 interested in all aspects of Medicine
S G Thompson, H A Ashton, L Gao, M J Buxton, R A P Scott
BACKGROUND: The long-term effects of abdominal aortic aneurysm (AAA) screening were investigated in extended follow-up from the UK Multicentre Aneurysm Screening Study (MASS) randomized trial. METHODS: A population-based sample of men aged 65-74 years were randomized individually to invitation to ultrasound screening (invited group) or to a control group not offered screening. Patients with an AAA (3·0 cm or larger) detected at screening underwent surveillance and were offered surgery after predefined criteria had been met...
December 2012: British Journal of Surgery
Katherine H Chau, John A Elefteriades
Thoracic aortic aneurysms (TAAs) are a prevalent and deadly disease that, without diagnosis and treatment, eventuates in life-threatening aortic dissection or rupture. While TAAs normally grow in an indolent manner, once a certain size (a "hinge point") is reached, the risk of dissection, rupture, and death increases dramatically. By virtue of their common clinical "silence," many TAAs are not diagnosed until such complications occur. While size is a helpful criterion for intervention, there is a need for parameters and markers besides aortic aneurysm size for use in diagnosing and monitoring TAAs so as to prevent natural complications of this disease...
July 2013: Progress in Cardiovascular Diseases
Joris Wansink, Frank G H van der Kleij
A 74-year-old man presented with acute back pain but without neurologic symptoms. The blood pressure was normal. He had a history of hypertension, open repair of an aortic infrarenal aneurysm, and end-stage renal failure that required hemodialysis. Computed tomography revealed a thoracic aneurysm..
March 3, 2016: New England Journal of Medicine
Anna A Ahimastos, Philip J Walker, Christopher Askew, Anthony Leicht, Elise Pappas, Peter Blombery, Christopher M Reid, Jonathan Golledge, Bronwyn A Kingwell
IMPORTANCE: Approximately one-third of patients with peripheral artery disease experience intermittent claudication, with consequent loss of quality of life. OBJECTIVE: To determine the efficacy of ramipril for improving walking ability, patient-perceived walking performance, and quality of life in patients with claudication. DESIGN, SETTING, AND PATIENTS: Randomized, double-blind, placebo-controlled trial conducted among 212 patients with peripheral artery disease (mean age, 65...
February 6, 2013: JAMA: the Journal of the American Medical Association
Raimund Erbel, Victor Aboyans, Catherine Boileau, Eduardo Bossone, Roberto Di Bartolomeo, Holger Eggebrecht, Arturo Evangelista, Volkmar Falk, Herbert Frank, Oliver Gaemperli, Martin Grabenwöger, Axel Haverich, Bernard Iung, Athanasios John Manolis, Folkert Meijboom, Christoph A Nienaber, Marco Roffi, Hervé Rousseau, Udo Sechtem, Per Anton Sirnes, Regula S von Allmen, Christiaan J M Vrints
No abstract text is available yet for this article.
November 1, 2014: European Heart Journal
Dharam J Kumbhani, Ph Gabriel Steg, Christopher P Cannon, Kim A Eagle, Sidney C Smith, Shinya Goto, E Magnus Ohman, Yedid Elbez, Piyamitr Sritara, Iris Baumgartner, Subhash Banerjee, Mark A Creager, Deepak L Bhatt
AIMS: Due to a high burden of systemic cardiovascular events, current guidelines recommend the use of statins in all patients with peripheral artery disease (PAD). We sought to study the impact of statin use on limb prognosis in patients with symptomatic PAD enrolled in the international REACH registry. METHODS: Statin use was assessed at study enrolment, as well as a time-varying covariate. Rates of the primary adverse limb outcome (worsening claudication/new episode of critical limb ischaemia, new percutaneous/surgical revascularization, or amputation) at 4 years and the composite of cardiovascular death/myocardial infarction/stroke were compared among statin users vs...
November 1, 2014: European Heart Journal
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