collection
https://read.qxmd.com/read/27510942/managing-migraine
#21
REVIEW
Benjamin W Friedman
No abstract text is available yet for this article.
February 2017: Annals of Emergency Medicine
https://read.qxmd.com/read/26141299/headache-management-pharmacological-approaches
#22
REVIEW
Alex J Sinclair, Aaron Sturrock, Brendan Davies, Manjit Matharu
Headache is one of the most common conditions presenting to the neurology clinic, yet a significant proportion of these patients are unsatisfied by their clinic experience. Headache can be extremely disabling; effective treatment is not only essential for patients but is rewarding for the physician. In this first of two parts review of headache, we provide an overview of headache management, emerging therapeutic strategies and an accessible interpretation of clinical guidelines to assist the busy neurologist...
December 2015: Practical Neurology
https://read.qxmd.com/read/25841032/reduced-efficacy-of-sumatriptan-in-migraine-with-aura-vs-without-aura
#23
RANDOMIZED CONTROLLED TRIAL
Jakob Møller Hansen, Peter J Goadsby, Andrew Charles
OBJECTIVE: To determine whether acute migraine treatment outcome is different in migraine with aura compared with migraine without aura. METHODS: We examined pooled outcome data for sumatriptan treatment of migraine with and without aura from the sumatriptan/naratriptan aggregate patient database. We also examined similar outcome data for inhaled dihydroergotamine (DHE) from a single, large randomized controlled study. RESULTS: The pooled pain-free rates 2 hours postdose for sumatriptan 100 mg were significantly higher in patients treating attacks without aura (32%) compared with the group who treated attacks with aura (24%) (p < 0...
May 5, 2015: Neurology
https://read.qxmd.com/read/25932693/brain-aging-in-female-migraineurs-differences-in-the-insula
#24
COMMENT
Frank Seifert
No abstract text is available yet for this article.
July 2015: Pain
https://read.qxmd.com/read/25711410/how-effective-is-melatonin-as-a-preventive-treatment-for-hemicrania-continua-a-clinic-based-study
#25
JOURNAL ARTICLE
Todd D Rozen
OBJECTIVE: To assess the efficacy of melatonin as a preventive therapy for hemicrania continua in a larger population of patients than has previously been studied. BACKGROUND: Hemicrania continua is defined by its sensitivity to indomethacin. Rarely can patients be fully tapered off indomethacin without headache recurrence; thus, the risks associated with chronic indomethacin usage are substantial for these individuals. Melatonin, a pineal hormone with a similar chemical structure to indomethacin, has shown efficacy as a preventive agent for hemicrania continua in isolated case reports...
March 2015: Headache
https://read.qxmd.com/read/25773005/drug-safety-in-acute-migraine-treatment
#26
REVIEW
János Tajti, Zsófia Majláth, Délia Szok, Anett Csáti, László Vécsei
INTRODUCTION: A number of drugs are available for acute migraine treatment, but they are not all effective for all patients and all attacks. The safety profiles of migraine drugs limit their use in patients with certain comorbid conditions, and adverse effects may also reduce the level of patient compliance. AREAS COVERED: The different types of acute migraine drugs are discussed, with particular regard to safety issues and potential adverse effects. The frequent use of analgesics, ergot alkaloids and triptans may result in the development of medication overuse headache (MOH)...
June 2015: Expert Opinion on Drug Safety
https://read.qxmd.com/read/23963471/high-rate-repetitive-transcranial-magnetic-stimulation-in-migraine-prophylaxis-a-randomized-placebo-controlled-study
#27
RANDOMIZED CONTROLLED TRIAL
Usha K Misra, Jayantee Kalita, Sanjeev K Bhoi
Repetitive transcranial magnetic stimulation (rTMS) is an emerging treatment for pain but there is no class 1 study on its role in migraine prophylaxis. In this study we report the efficacy and safety of high-rate rTMS in migraine prophylaxis. Adult migraine patients having >4 attacks/month were randomized to high-rate rTMS or sham stimulation. Stimulation in the form of 10 Hz rTMS, 600 pulses in 10 trains were delivered to the hot spot of the right abductor digiti minimi in 412 s. Three sessions were delivered on alternate days...
November 2013: Journal of Neurology
https://read.qxmd.com/read/12167135/chronic-daily-headache-prophylaxis-with-tizanidine-a-double-blind-placebo-controlled-multicenter-outcome-study
#28
RANDOMIZED CONTROLLED TRIAL
Joel R Saper, Alvin E Lake, Deborah T Cantrell, Paul K Winner, Jeffery R White
OBJECTIVE: To assess the efficacy of tizanidine hydrochloride versus placebo as adjunctive prophylactic therapy for chronic daily headache (chronic migraine, migrainous headache, or tension-type headache). BACKGROUND: Tizanidine is an alpha2-adrenergic agonist that inhibits the release of norepinephrine at both the spinal cord and brain, with antinociceptive effects that are independent of the endogenous opioid system. Previous open-label studies have suggested the drug may be effective for treatment of chronic daily headache...
June 2002: Headache
https://read.qxmd.com/read/22683887/canadian-headache-society-guideline-for-migraine-prophylaxis
#29
JOURNAL ARTICLE
Tamara Pringsheim, W Jeptha Davenport, Gordon Mackie, Irene Worthington, Michel Aubé, Suzanne N Christie, Jonathan Gladstone, Werner J Becker
OBJECTIVES: The primary objective of this guideline is to assist the practitioner in choosing an appropriate prophylactic medication for an individual with migraine, based on current evidence in the medical literature and expert consensus. This guideline is focused on patients with episodic migraine (headache on ≤ 14 days a month). METHODS: Through a comprehensive search strategy, randomized, double blind, controlled trials of drug treatments for migraine prophylaxis and relevant Cochrane reviews were identified...
March 2012: Canadian Journal of Neurological Sciences. le Journal Canadien des Sciences Neurologiques
https://read.qxmd.com/read/25023977/efficacy-and-safety-of-cinnarizine-in-the-prophylaxis-of-migraine-in-children-a-double-blind-placebo-controlled-randomized-trial
#30
RANDOMIZED CONTROLLED TRIAL
Mahmoud Reza Ashrafi, Soodeh Salehi, Reza Azizi Malamiri, Morteza Heidari, Seyed Ahmad Hosseini, Mahboubeh Samiei, Ali Reza Tavasoli, Mansoureh Togha
BACKGROUND: In spite of the high occurrence of migraine headaches in school-age children, there are currently no approved and widely accepted pharmacologic agents for migraine prophylaxis in children. Our previous open-label study in children revealed the efficacy of cinnarizine, a calcium channel blocker, in migraine prophylaxis. A placebo-controlled trial was conducted to demonstrate the efficacy and safety of cinnarizine in the prophylaxis of migraine in children. TRIAL DESIGN: A double-blind, placebo-controlled, parallel-group study conducted in a tertiary medical center in Tehran, Iran...
October 2014: Pediatric Neurology
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