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Adherence in Kidney Disease

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130 papers 25 to 100 followers
By Isabel Acosta-Ochoa Nephrology senior staff. Valladolid. Spain
Esra Başer, Mukadder Mollaoğlu
INTRODUCTION: Some hemodialysis patients may experience problems in completing activities of daily living and adhering to diet and fluid restrictions due to a decrease in self-care power and a loss of competence. METHODS: The study was conducted with 78 people assigned to the intervention (N = 38) and control groups (N = 40). Data were collected using the sociodemographic characteristics questionnaire, dialysis diet and fluid nonadherence questionnaire (DDFQ), and fluid control in hemodialysis patients scale (FCHPS)...
March 12, 2019: Hemodialysis International
Stefano Balducci, Valeria D'Errico, Jonida Haxhi, Massimo Sacchetti, Giorgio Orlando, Patrizia Cardelli, Martina Vitale, Lucilla Bollanti, Francesco Conti, Silvano Zanuso, Giuseppe Lucisano, Antonio Nicolucci, Giuseppe Pugliese
Importance: There is no definitive evidence that changes in physical activity/sedentary behavior can be maintained long term in individuals with type 2 diabetes. Objective: To investigate whether a behavioral intervention strategy can produce a sustained increase in physical activity and reduction in sedentary time among individuals with type 2 diabetes. Design, Setting, and Participants: The Italian Diabetes and Exercise Study 2 was an open-label, assessor-blinded, randomized clinical superiority trial, with recruitment from October 2012 to February 2014 and follow-up until February 2017...
March 5, 2019: JAMA: the Journal of the American Medical Association
Jewell Robinson Parker
Fluid restriction is a major lifestyle change for patients with end stage renal disease who are on hemodialysis. Educating patients about fluid management supports self-management of their prescribed fluid restrictions. Using a pre-test/post-test design, this project aimed to educate 17 patients on chronic hemodialysis about the management of fluid restrictions for improved renal fluid adherence. Post-intervention assessments revealed increased knowledge of hemodialysis treatment and improved renal fluid adherence...
January 2019: Nephrology Nursing Journal: Journal of the American Nephrology Nurses' Association
Simon R Knight
Successful renal transplantation requires lifelong immunosuppression, usually with a combination of drugs, to prevent rejection and immunologically-mediated damage to the graft. To achieve maximum effect, these immunosuppressive agents must be taken regularly as prescribed. This is particularly true of critical-dose drugs such as tacrolimus, with a narrow therapeutic window between efficacy and toxicity. This article is protected by copyright. All rights reserved.
March 1, 2019: Transplant International: Official Journal of the European Society for Organ Transplantation
Saurav Ghimire, Kenneth Lee, Matthew D Jose, Ronald L Castelino, Syed Tabish R Zaidi
AIMS AND OBJECTIVES: To explore clinician assessment of patient adherence, and identify strategies to improve adherence assessment practices in haemodialysis settings. BACKGROUND: Patients with chronic kidney disease undergoing haemodialysis are typically prescribed complex regimens; as such, they are at high risk of medication nonadherence. Current clinical practices focus on prescribing medications, however, little attention is paid to measuring and ensuring patient adherence to their prescribed treatments...
February 20, 2019: Journal of Clinical Nursing
Krystina Parker, Ingrid Bull-Engelstad, Willy Aasebø, Nanna von der Lippe, Morten Reier-Nilsen, Ingrid Os, Knut Stavem
INTRODUCTION: Elderly patients with chronic kidney disease (CKD) stage 5 with or without dialysis treatment usually have concomitant comorbidities, which often result in multiple pharmacological therapies. This study aimed to identify factors associated with medication complexity and medication adherence, as well as the association between medication complexity and medication adherence, in elderly patients with CKD. METHODS: This prospective study involved elderly patients with CKD stage 5 (estimated glomerular filtration rate < 15 ml/min/1...
February 19, 2019: Hemodialysis International
Kathryn Gray, Linda H Ficociello, Abigail E Hunt, Claudy Mullon, Steven M Brunelli
Background: Phosphate binders are widely used to achieve serum phosphorus control in patients with end-stage renal disease. However, the large pill burden associated with these medications may decrease adherence to therapy. In clinical trials, sucroferric oxyhydroxide (SO) demonstrated equivalent control of serum phosphorus to sevelamer, with a lower daily pill burden. We examined changes in phosphate binder pill burden, medication possession ratio (MPR), and phosphorus control among in-center hemodialysis (ICHD) patients converting to SO from another phosphate binder as part of routine care...
2019: International Journal of Nephrology and Renovascular Disease
Marte Theie Gustavsen, Karsten Midtvedt, Kjersti Lønning, Thea Jacobsen, Anna V Reisaeter, Sabina De Geest, Marit Helen Andersen, Anders Hartmann, Anders Åsberg
BACKGROUND: Annual assessment of adherence would strengthen long-term outcome assessments from registry data. The objective of this study was to evaluate tools suitable for annual routine capture of adherence data in renal transplant recipients. METHODS: A single centre open prospective trial included 295 renal transplant recipients on tacrolimus. Two thirds of the patients were included 4-weeks post-transplant, randomised 1:1 to intensive or single-point adherence assessment in the early phase and 1-year post-transplant...
February 15, 2019: Transplant International: Official Journal of the European Society for Organ Transplantation
Nurten Ozen, Fatma Ilknur Cinar, Dilek Askin, Dilek Mut, Turker Turker
BACKGROUND: Nonadherence to dietary and fluid restrictions, hemodialysis (HD), and medication treatment has been shown to increase the risks of hospitalization and mortality significantly. Sociodemographic and biochemical parameters as well as psychosocial conditions such as depression and anxiety are known to affect nonadherence in HD patients. However, evidence related to the relative importance and actual impact of these factors varies among studies. PURPOSE: The aim of this study was to identify the factors that affect nonadherence to dietary and fluid restrictions, HD, and medication treatment...
January 31, 2019: Journal of Nursing Research: JNR
David J Taber, Mulugeta Gebregziabher, Aurora Posadas, Caitlin Schaffner, Leonard E Egede, Prabhakar K Baliga
Introduction: Health disparities in African-American (AA) kidney transplant recipients compared with non-AA recipients are well established. Cardiovascular disease (CVD) risk control is a significant mediator of this disparity. Objective: To assess the efficacy of improved medication safety, CVD risk control, and racial disparities in kidney transplant recipients. Methods: Prospective, pharmacist-led, technology-aided, 6-month interventional clinical trial...
December 2018: Journal of the American College of Clinical Pharmacy: JAACP
Sarah H Drangsholt, Ulrik W Cappelen, Nanna von der Lippe, Aud Høieggen, Ingrid Os, Fredrik B Brekke
INTRODUCTION: Patients with end-stage renal disease are burdened by a complex medication regimen, but little is known about the belief about medicine among dialysis- and renal transplant (RTX) patients. Patients' beliefs about medicines may influence drug adherence and thereby affect morbidity and mortality. The aim of the present study was to assess the beliefs about medicine in dialysis as well as after RTX. METHODS: In a prospective study, 301 dialysis patients were followed for up to 5...
February 4, 2019: Hemodialysis International
Ok Lae Park, Sung Reul Kim
AIM: To evaluate the effects of an integrated self-management program using a mobile application, a short message service using a smartphone, and face-to-face counseling and education among hemodialysis patients. METHODS: A quasi-experimental study design was used. The participants of this study were 84 hemodialysis patients (42 in the experimental group and 42 in the control group). The experimental group received the integrated self-management program for 8 weeks...
January 22, 2019: Japan Journal of Nursing Science: JJNS
Lydia Lissanu, Fanny Lopez, Akilah King, Eric Robinson, Erik Almazan, Gabrielle Metoyer, Michael Quinn, Monica E Peek, Milda R Saunders
CONTEXT: African-Americans with chronic kidney disease (CKD) are more likely to progress to end-stage renal disease (ESRD). However, African-Americans are less likely to receive care to delay progression of their CKD and to prepare for ESRD treatment. OBJECTIVE: The objectives of the study are to understand knowledge among urban, African-American patients diagnosed with CKD and to discover ways they managed their illness and prepared for kidney disease progression...
January 17, 2019: Journal of Racial and Ethnic Health Disparities
Kamlesh Khunti, Mark D Danese, Lucie Kutikova, David Catterick, Francisco Sorio-Vilela, Michelle Gleeson, Sreenivasa Rao Kondapally Seshasai, Jack Brownrigg, Kausik K Ray
Importance: Both adherence and treatment intensity can alter the effectiveness of lipid-lowering therapy in routine clinical practice. Objective: To evaluate the association of adherence and treatment intensity with cardiovascular outcomes in patients with documented cardiovascular disease (CVD), type 2 diabetes without CVD or chronic kidney disease (CKD), and CKD without CVD. Design, Setting, and Participants: Retrospective cohort study using the Clinical Practice Research Datalink from January 2010 through February 2016...
December 7, 2018: JAMA network open
K Griva, M Rajeswari, M Nandakumar, E Y H Khoo, V Y W Lee, C G Chua, Z S Goh, Y T D Choong, S P Newman
BACKGROUND: This cluster randomised controlled trial set out to investigate the feasibility and acceptability of the "Combined Diabetes and Renal Control Trial" (C-DIRECT) intervention, a nurse-led intervention based on motivational interviewing and self-management in patients with coexisting end stage renal diseases and diabetes mellitus (DM ESRD). Its efficacy to improve glycaemic control, as well as psychosocial and self-care outcomes were also evaluated as secondary outcomes...
January 3, 2019: BMC Nephrology
Azam Mahjubian, Nasrin Bahraminejad, Koorosh Kamali
Introduction: Improving self-management of the patients undergoing hemodialysis is an effective way to reduce complications and to improve the quality of life of them. The current study aims to assess the effects of group discussion on the promotion of self-management behaviors in hemodialysis patients. Methods: In this quasi -experimental clinical trial study (with experimental and control groups) 60 patients were arranged in two experimental and control groups through using convenience sampling with random allocation...
December 2018: Journal of Caring Sciences
Sarah J Schrauben, Jesse Y Hsu, Julie Wright Nunes, Michael J Fischer, Anand Srivastava, Jing Chen, Jeanne Charleston, Susan Steigerwalt, Thida C Tan, Jeffrey C Fink, Ana C Ricardo, James P Lash, Myles Wolf, Harold I Feldman, Amanda H Anderson
Introduction: A cornerstone of kidney disease management is participation in guideline-recommended health behaviors. However, the relationship of these health behaviors with outcomes, and the identification of barriers to health behavior engagement, have not been described among younger and older adults with chronic kidney disease. Methods: Data from a cohort study of 5499 individuals with chronic kidney disease was used to identify health behavior patterns with latent class analysis stratified by age <65 and ≥65 years...
January 2019: KI Reports
Dudith Pierre-Victor, Paul F Pinsky
Importance: Patient nonadherence to chronic disease prevention guidelines is associated with increased mortality. Nonadherence to offered cancer screening tests may be associated with mortality among middle-aged and older adults. Objective: To evaluate the association between nonadherence to cancer screening tests and mortality in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening trial, excluding mortality from cancers studied in the trial. Design, Setting, and Participants: Randomization at 10 US screening centers occurred from November 8, 1993, to July 2, 2001...
December 28, 2018: JAMA Internal Medicine
S M Zhao, F F Dong, H Z Qiu, D Li
BACKGROUND: Quality of life (QoL) is an important indicator for evaluating therapeutic outcomes and mortality in renal transplant recipients, but there is scarce information regarding QoL, adherence behavior, social support and their relationships. This study assessed these factors among renal transplant recipients. METHODS: Using a descriptive, correlational, cross-sectional design, this study included a convenience sample of 253 kidney transplant recipients. Structured questionnaires were used to collect data...
December 2018: Transplantation Proceedings
Ayeesha Kamran Kamal, Wardah Khalid, Abdul Muqeet, Anum Jamil, Kashfa Farhat, Sehar Rahim Ali Gillani, Maryam Zulfiqar, Mehreen Saif, Aliya Amin Muhammad, Fabiha Zaidi, Mohammad Mustafa, Ambreen Gowani, Shahrukh Sharif, Syedah Saira Bokhari, Javed Tai, Nasir Rahman, Fateh Ali Tipoo Sultan, Saleem Sayani, Salim S Virani
BACKGROUND: We developed and tested the effectiveness of a tailored health information technology driven intervention: "Talking Prescriptions" (Talking Rx) to improve medication adherence in a resource challenged environment. METHODS: We conducted a parallel, randomized, controlled, assessor-blinded trial at the Aga Khan University (AKU), Karachi, Pakistan. Adults with diagnosis of cerebrovascular accident (CVA) or coronary artery disease (CAD) diagnosed least one month before enrollment, on anti-platelets and statins, with access to a mobile phone were enrolled...
2018: PloS One
2018-12-24 09:01:20
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