Amy C Plint, David W Johnson, Hema Patel, Natasha Wiebe, Rhonda Correll, Rollin Brant, Craig Mitton, Serge Gouin, Maala Bhatt, Gary Joubert, Karen J L Black, Troy Turner, Sandra Whitehouse, Terry P Klassen
BACKGROUND: Although numerous studies have explored the benefit of using nebulized epinephrine or corticosteroids alone to treat infants with bronchiolitis, the effectiveness of combining these medications is not well established. METHODS: We conducted a multicenter, double-blind, placebo-controlled trial in which 800 infants (6 weeks to 12 months of age) with bronchiolitis who were seen in the pediatric emergency department were randomly assigned to one of four study groups...
May 14, 2009: New England Journal of Medicine