A Själander, J-H Jansson, D Bergqvist, H Eriksson, B Carlberg, P Svensson
OBJECTIVES: Venous thromboembolism (VTE) is a potentially serious complication of hospitalization and immobilization. The use of anticoagulant prophylaxis in acutely ill medical inpatients is still under debate. New data including a recent meta-analysis have recently been published. We aim at studying the efficacy and safety of anticoagulant prophylaxis in acutely ill medical inpatients, and demonstrate differences between meta-analyses due to different data extraction from the heterogeneous studies included...
January 2008: Journal of Internal Medicine
James P Stannard, Robert R Lopez-Ben, David A Volgas, Edward R Anderson, Matt Busbee, Donna K Karr, Gerald R McGwin, Jorge E Alonso
BACKGROUND: Deep-vein thrombosis following skeletal trauma is an important yet poorly studied issue. The purpose of the present study was to evaluate the efficacy of two different strategies for prophylaxis against deep-vein thrombosis and pulmonary embolus following blunt skeletal trauma. METHODS: Two hundred and twenty-four inpatients were enrolled in a prospective, randomized study investigating venous thromboembolic disease following trauma. Two hundred patients completed the study, which compared two different regimens of prophylaxis...
February 2006: Journal of Bone and Joint Surgery. American Volume
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