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https://read.qxmd.com/read/24382724/intrawound-vancomycin-powder-eradicates-surgical-wound-contamination-an-in-vivo-rabbit-study
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JOURNAL ARTICLE
Lukas P Zebala, Tapanut Chuntarapas, Michael P Kelly, Michael Talcott, Suellen Greco, K Daniel Riew
BACKGROUND: Surgical site infection remains a complication of spine surgery despite routine use of prophylactic antibiotics. Retrospective clinical studies of intrawound vancomycin use have documented a decreased prevalence of surgical site infection after spine surgery. The purpose of the present study was to assess the efficacy of intrawound vancomycin powder in terms of eradicating a known bacterial surgical site contamination in a rabbit spine surgery model. METHODS: Twenty New Zealand White rabbits underwent lumbar partial laminectomy and wire implantation...
January 1, 2014: Journal of Bone and Joint Surgery. American Volume
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