Imran H Yusuf, Ruofan C Han, Susan M Downes, Srilakshmi M Sharma
BACKGROUND: The risk of developing hydroxychloroquine retinopathy is considered sufficient to justify national monitoring programmes. There are an estimated 71,144-77,170 long-term hydroxychloroquine users in the UK. However, the number of patients diagnosed with retinopathy is unknown. This study aimed to identify the number of cases and clinical characteristics of hydroxychloroquine retinopathy diagnosed annually in hospital eye services across the UK. METHODS: A nationwide, prospective case ascertainment study was undertaken using the British Ophthalmological Surveillance Unit, which sends approximately 1420 reporting cards to UK Ophthalmologists monthly...
November 15, 2022: Eye
Wissam Aljundi, Loay Daas, Yaser Abu Dail, Barbara Käsmann-Kellner, Berthold Seitz, Alaa Din Abdin
PURPOSE: To investigate the effectiveness of nonsteroidal anti-inflammatory eye drops (NSAIDs) combined with oral acetazolamide for postoperative macular edema (PME) after uncomplicated phacoemulsification (PE) and identify predictors of non-response. METHODS: We analyzed data of uncomplicated PE and identified eyes with PME. First-line therapy included topical NSAIDs combined with oral acetazolamide. In the case of non-response, triamcinolone was administered subtenonally...
September 21, 2022: Journal of Clinical Medicine
Diana V Do, Hadi Moini, Charles C Wykoff
No abstract text is available yet for this article.
August 2022: BMJ Open Ophthalmology
Chaitra Jayadev, Ishank Gupta, Santosh Gopi Krishna Gadde
Purpose: To report a case of bilateral refractory macular edema in a diabetic macular edema in a diabetic with an underlying systemic illness. Case Report: A 65-year-old male presented with the symptom of blurred vision in both eyes for three months. He was a known diabetic patient and was also hypertensive for the last 10 years. The corrected distance visual acuity was 20/120 in the right eye and 20/80 in the left eye. Fundus examination revealed multiple deep and superficial retinal hemorrhages, cystoid macular edema, and serous macular detachment in both eyes...
July 2022: Journal of Ophthalmic & Vision Research
Mélanie Hébert, Eunice You, Jean-François Gravel, Ali Dirani, Serge Bourgault
Purpose: To describe a case of posterior scleritis following anti-vascular endothelial growth factor (VEGF) injection. Observations: A 51-year-old male receiving biweekly anti-VEGF injections for a central retinal vein occlusion complicated with cystoid macular edema presented with new-onset severe pain, photophobia, and tearing. Ophthalmological examination revealed choroidal folds and B-scan ultrasound confirmed significant thickening of the sclera, leading to a diagnosis of posterior scleritis...
December 2022: American Journal of Ophthalmology Case Reports
Aaron Veenis, Megan Haghnegahdar, Radwan Ajlan
BACKGROUND: Mycobacterium chimaera ocular infection is a rare disease that is linked to bypass devices used during cardiothoracic surgeries. Reported cases in the literature of ocular involvement preceding CNS involvement are based on clinical exam with no neuroimaging. Here we present a case of M. chimaera ocular infection with no CNS M. chimaera lesions on brain magnetic resonance imaging (MRI). CASE PRESENTATION: A 59-year-old female presented with altered mental status and blurred vision in February 2021...
July 22, 2022: BMC Ophthalmology
Chae-Min Hong, Min-Ho Shin, Seong-Jae Kim, Seong-Wook Seo, Inyoung Chung, Woong-Sun Yoo
BACKGROUND: Posterior scleritis is a rare, inflammatory ophthalmic disease, leading to severe visual impairment if untreated. Posterior scleritis occurring after surgery, unrelated to systemic inflammatory diseases, is even rarer. This report discusses a case of bilateral posterior scleritis, after cataract surgery in both the eyes, treated with high-dose steroids. CASE PRESENTATION: A 55-year-old man, who had undergone bilateral sequential cataract surgery one week before, presented with sudden loss of vision and ocular pain in both eyes...
July 26, 2022: BMC Ophthalmology
Tomislav Sarenac, Anela Bečić Turkanović, Peter Ferme, Tomaž Gračner
Presently, there is no efficacious treatment for glaucomatous optic neuropathy; the current treatment is focused on lowering intraocular pressure (IOP). Studies have demonstrated the safety and efficacy of selective laser trabeculoplasty (SLT) in reducing the IOP in eyes with open-angle (OAG) glaucoma or ocular hypertension (OH). Moreover, the European Glaucoma Society has instated SLT as the first-line or adjunctive treatment in OAG or OH, reiterating its clinical significance. In this review, we outline the old and the new roles of SLT, with an emphasis on clinical practice, and look further into its renewed appeal and future developments...
July 4, 2022: Journal of Clinical Medicine
Jonathan Malcolm, Christopher Leak, Alexander C Day, Helen Baker, John C Buchan
BACKGROUND: Recent national data suggests that less than 0.5% of NHS cataract patients undergo immediate sequential bilateral cataract surgery (ISBCS). Since ISBCS improves service efficiency, increasing its practice may help tackle the ever-growing burden of cataract in the UK, and reduce the COVID-19 cataract backlog. Surgeon attitudes are known to be a significant barrier to increasing the practice of ISBCS. However, little is known about patient perceptions of ISBCS. METHODS: Patients at cataract clinics across three NHS hospital sites were recruited to complete an investigator-led structured questionnaire...
July 20, 2022: Eye
Murat Yüksel, Hüseyin Baran Özdemir, Şengül Özdek, Gökhan Gürelik
PURPOSE: To report the diagnosis, treatment and follow-up of a case of bilateral acute iris transillumination (BAIT) developed after COVID-19 pneumonia. METHOD: Case report. CASE: A 66-year-old male patient with COVID-19 pneumonia received systemic treatments of favipiravir, prednisolone, moxifloxacin and piperacillin-tazobactam during hospitalization. The patient applied to our clinic with the complaint of blurred vision 20 days after the diagnosis of COVID-19...
July 19, 2022: European Journal of Ophthalmology
Einar Stefansson, Thorstein Loftsson, Michael Larsen, András Papp, Kai Kaarniranta, Marion R Munk, Pravin Dugel, Ramin Tadayoni
PURPOSE: To evaluate topical dexamethasone ophthalmic suspension OCS-01 (Oculis SA, Lausanne, Switzerland) in diabetic macular edema (DME). METHODS: This was a multicenter, double-masked, parallel-group, randomized, Phase 2 study. Patients aged 18-85 years with DME of <3 years duration, ETDRS central subfield thickness ≥ 310 μm by SD-OCT, and ETDRS letter score ≤ 73 and ≥ 24 in the study eye were randomized 2:1 to OCS-01 or matching vehicle, 1 drop 3 times/day for 12 weeks...
July 18, 2022: Acta Ophthalmologica
Erin R Sherman, Malinda Cafiero-Chin
Uveitic glaucoma is a range of disorders that results in optic nerve damage from elevated intraocular pressure secondary to intraocular inflammation. As compared to primary open angle glaucoma, uveitic glaucoma is associated with a more aggressive disease course caused by very high intraocular pressure levels that wax and wane. Diagnosis is often based on clinical presentation, disease course, and associated systemic manifestations. Diagnostic imaging plays an important role in both diagnosis and management...
March 2019: Clinical & Experimental Optometry: Journal of the Australian Optometrical Association
Els M Pameijer, Pauline Heus, Johanna A A Damen, René Spijker, Lotty Hooft, Peter J Ringens, Saskia M Imhof, Redmer van Leeuwen
The aim of this paper is to summarize all available evidence from systematic reviews, randomized controlled trials (RCTs) and comparative nonrandomized studies (NRS) on the association between nutrition and antioxidant, vitamin, and mineral supplements and the development or progression of age-related macular degeneration (AMD). The Cochrane Database of Systematic Reviews, Cochrane register CENTRAL, MEDLINE and Embase were searched and studies published between January 2015 and May 2021 were included. The certainty of evidence was assessed according to the GRADE methodology...
June 13, 2022: Acta Ophthalmologica
Kathrine Blom, Øystein Kalsnes Jørstad, Rowan Thomas Faber, Ingar Stene-Johansen, Mona Holberg-Petersen, Nils Olav Hermansen, Ragnheiður Bragadóttir
BACKGROUND/AIMS: To compare outcomes of acute endophthalmitis (EO) managed with either primary vitrectomy (PV) or primary intravitreal antibiotics (vancomycin and ceftazidime) followed by early vitrectomy (PIAEV) combined with polymerase chain reaction (PCR)-based diagnostics. METHODS: This was a prospective, comparative observational study of acute EO cases admitted to a regional vitreoretinal service over 18 months. Depending on whether immediate vitrectomy (within 6 h) was achievable, the EO cases were treated with either (1) PV or (2) PIAEV...
June 25, 2022: Acta Ophthalmologica
Usha Chakravarthy, Beatriz G Armendariz, Sascha Fauser
No abstract text is available yet for this article.
June 25, 2022: Eye
Paul J Foster, Wai Siene Ng, Winifred P Nolan, Luke Tanner, Gus Gazzard, Alex C Day, Roshini Sanders, Barny Foot, John F Salmon, Augusto Azuara-Blanco
No abstract text is available yet for this article.
June 20, 2022: Eye
Shruti Chandra, Martin McKibbin, Sajjad Mahmood, Louise Downey, Beth Barnes, Sobha Sivaprasad
No abstract text is available yet for this article.
May 27, 2022: Eye
George Murphy, Raisah Owasil, Sam Kanavati, Zahra Ashena, Mayank A Nanavaty
PURPOSE: To assess the proportion of maculopathy detectable only on optical coherence tomography (OCT) versus slit lamp indirect ophthalmoscopy (SLIO) during cataract assessment. METHODS: Population: Consecutive patients attending cataract assessments. DATA COLLECTION: All patients underwent OCT and SLIO. SLIO findings were recorded before reviewing OCT. Scans were examined to compare with recorded SLIO findings. PRIMARY OUTCOME: analyse the proportion of eyes with maculopathy missed by SLIO...
March 24, 2022: Eye
Rupali Singh, Samaneh Davoudi, Steven Ness
BACKGROUND: Intravitreal medication injections represent the gold standard treatment for a variety of potentially blinding chorioretinal vascular diseases. Despite their excellent safety profile, they are associated with the feared complication of injection-related endophthalmitis (IRE). Though the overall incidence of IRE is low, due to the ever-increasing number of injections being performed, it is a complication that all retina specialists are likely to encounter. This article reviews various factors that could potentially influence the risk of IRE and discusses evidence-based strategies for management...
March 12, 2022: Graefe's Archive for Clinical and Experimental Ophthalmology
Dimitrios Kalogeropoulos, Hercules Sakkas, Bashar Mohammed, Georgios Vartholomatos, Konstantinos Malamos, Sreekanth Sreekantam, Panagiotis Kanavaros, Chris Kalogeropoulos
PURPOSE: This review aims to summarize the current knowledge concerning the clinical features, diagnostic work-up and therapeutic approach of ocular toxoplasmosis focusing mainly on the postnatally acquired form of the disease. METHODS: A meticulous literature search was performed in the PubMed database. A supplementary search was made in Google Scholar to complete the collected items. RESULTS: Ocular toxoplasmosis is one of the most frequent infectious etiologies of posterior uveitis...
January 2022: International Ophthalmology
2022-03-07 23:24:42
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