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Afshin Parsa, W H Linda Kao, Dawei Xie, Brad C Astor, Man Li, Chi-yuan Hsu, Harold I Feldman, Rulan S Parekh, John W Kusek, Tom H Greene, Jeffrey C Fink, Amanda H Anderson, Michael J Choi, Jackson T Wright, James P Lash, Barry I Freedman, Akinlolu Ojo, Cheryl A Winkler, Dominic S Raj, Jeffrey B Kopp, Jiang He, Nancy G Jensvold, Kaixiang Tao, Michael S Lipkowitz, Lawrence J Appel
BACKGROUND: Among patients in the United States with chronic kidney disease, black patients are at increased risk for end-stage renal disease, as compared with white patients. METHODS: In two studies, we examined the effects of variants in the gene encoding apolipoprotein L1 (APOL1) on the progression of chronic kidney disease. In the African American Study of Kidney Disease and Hypertension (AASK), we evaluated 693 black patients with chronic kidney disease attributed to hypertension...
December 5, 2013: New England Journal of Medicine
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