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REVIEW
Hugh J Willison, Bart C Jacobs, Pieter A van Doorn
Guillain-Barré syndrome is the most common and most severe acute paralytic neuropathy, with about 100,000 people developing the disorder every year worldwide. Under the umbrella term of Guillain-Barré syndrome are several recognisable variants with distinct clinical and pathological features. The severe, generalised manifestation of Guillain-Barré syndrome with respiratory failure affects 20-30% of cases. Treatment with intravenous immunoglobulin or plasma exchange is the optimal management approach, alongside supportive care...
August 13, 2016: Lancet
#2
EDITORIAL
M Smith
No abstract text is available yet for this article.
October 2015: British Journal of Anaesthesia
#3
EDITORIAL
Chad A Asplund, Thomas M Best
No abstract text is available yet for this article.
2015: BMJ: British Medical Journal
#4
REVIEW
Stefan Wolf
PURPOSE OF REVIEW: The amount of blood in the basal cisterns is predictive for the final outcome after aneurysmal subarachnoid hemorrhage (SAH) and clinical problems such as delayed cerebral ischemia and angiographic vasospasm. A lumbar drainage presents an additional, physiologically appealing treatment. In contrast to an external ventricular drain, stasis of clots is thought to be prevented and clearance of the basal cisterns accelerated. In theory, patients with higher clinical grades and dense layers of subarachnoid blood should benefit most...
April 2015: Current Opinion in Critical Care
#5
RANDOMIZED CONTROLLED TRIAL
Jose-Miguel Yamal, M Laura Rubin, Julia S Benoit, Barbara C Tilley, Shankar Gopinath, H Julia Hannay, Pratik Doshi, Imoigele P Aisiku, Claudia S Robertson
Cerebral dysfunction caused by traumatic brain injury may adversely affect cerebral hemodynamics and oxygenation leading to worse outcomes if oxygen capacity is decreased due to anemia. In a randomized clinical trial of 200 patients comparing transfusion thresholds <7 g/dl versus 10 g/dl, where transfusion of leukoreduced packed red blood cells was used to maintain the assigned hemoglobin threshold, no long-term neurological difference was detected. The current study examines secondary outcome measures of intracranial pressure (ICP), cerebral perfusion pressure (CPP), and brain tissue oxygenation (PbtO2) in patients enrolled in this randomized clinical trial...
August 15, 2015: Journal of Neurotrauma
#6
JOURNAL ARTICLE
M Smith, G Citerio
No abstract text is available yet for this article.
January 2015: Intensive Care Medicine
#7
JOURNAL ARTICLE
Pierre Bouzat, Pedro Marques-Vidal, Jean-Baptiste Zerlauth, Nathalie Sala, Tamarah Suys, Patrick Schoettker, Jocelyne Bloch, Roy T Daniel, Marc Levivier, Reto Meuli, Mauro Oddo
OBJECTIVE: To examine the accuracy of brain multimodal monitoring-consisting of intracranial pressure, brain tissue PO2, and cerebral microdialysis--in detecting cerebral hypoperfusion in patients with severe traumatic brain injury. DESIGN: Prospective single-center study. PATIENTS: Patients with severe traumatic brain injury. SETTING: Medico-surgical ICU, university hospital. INTERVENTION: Intracranial pressure, brain tissue PO2, and cerebral microdialysis monitoring (right frontal lobe, apparently normal tissue) combined with cerebral blood flow measurements using perfusion CT...
February 2015: Critical Care Medicine
#8
EDITORIAL
John Strang, Sheila M Bird, Paul Dietze, Gilberto Gerra, A Thomas McLellan
No abstract text is available yet for this article.
November 4, 2014: BMJ: British Medical Journal
#9
JOURNAL ARTICLE
R Loch Macdonald, Michael N Diringer, Giuseppe Citerio
No abstract text is available yet for this article.
December 2014: Intensive Care Medicine
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