Huaixing Kang, Xiaomeng Xu, Kaifei Fu, Xioaping An, Zhiqiang Mi, Xiuyun Yin, Fan Peng, Guangqian Pei, Yahui Wang, Yong Huang, Xianglilan Zhang, Zhiyi Zhang, Wei Wang, Lijun Zhou, Jiankui Chen, Yigang Tong
Antibiotic-resistant opportunistic pathogens have become a serious concern in recent decades, as they are increasingly responsible for hospital-acquired infections. Here, we describe quinolone-resistant Delftia sp. strain 670, isolated from the sputum of a patient who died from severe pulmonary infection. The draft genome sequence of this strain was obtained by whole-genome shotgun sequencing, and was subjected to comparative genome analysis. Genome analysis revealed that one critical mutation (Ser83Ile in gyrA) might play a decisive role in quinolone resistance...
July 2015: Current Microbiology