collection
https://read.qxmd.com/read/25047577/antiretroviral-free-hiv-1-remission-and-viral-rebound-after-allogeneic-stem-cell-transplantation-report-of-2-cases
#21
JOURNAL ARTICLE
Timothy J Henrich, Emily Hanhauser, Francisco M Marty, Michael N Sirignano, Sheila Keating, Tzong-Hae Lee, Yvonne P Robles, Benjamin T Davis, Jonathan Z Li, Andrea Heisey, Alison L Hill, Michael P Busch, Philippe Armand, Robert J Soiffer, Marcus Altfeld, Daniel R Kuritzkes
BACKGROUND: It is unknown whether the reduction in HIV-1 reservoirs seen after allogeneic hematopoietic stem cell transplantation (HSCT) with susceptible donor cells is sufficient to achieve sustained HIV-1 remission. OBJECTIVE: To characterize HIV-1 reservoirs in blood and tissues and perform analytic antiretroviral treatment interruptions to determine the potential for allogeneic HSCT to lead to sustained, antiretroviral-free HIV-1 remission. DESIGN: Case report with characterization of HIV-1 reservoirs and immunity before and after antiretroviral interruption...
September 2, 2014: Annals of Internal Medicine
https://read.qxmd.com/read/25042757/pneumococcal-conjugate-vaccination-correlates-of-protection
#22
COMMENT
Angel Vila-Corcoles, Olga Ochoa-Gondar
No abstract text is available yet for this article.
September 2014: Lancet Infectious Diseases
https://read.qxmd.com/read/25042756/serotype-specific-effectiveness-and-correlates-of-protection-for-the-13-valent-pneumococcal-conjugate-vaccine-a-postlicensure-indirect-cohort-study
#23
JOURNAL ARTICLE
Nick J Andrews, Pauline A Waight, Polly Burbidge, Emma Pearce, Lucy Roalfe, Marta Zancolli, Mary Slack, Shamez N Ladhani, Elizabeth Miller, David Goldblatt
BACKGROUND: Efficacy of the 13-valent pneumococcal conjugate vaccine (PCV13) was inferred before licensure from an aggregate correlate of protection established for the seven-valent vaccine (PCV7). We did a postlicensure assessment of serotype-specific vaccine effectiveness and immunogenicity in England, Wales, and Northern Ireland to derive the correlates of protection for individual serotypes. METHODS: We assessed vaccine effectiveness against invasive pneumococcal disease using the indirect cohort method...
September 2014: Lancet Infectious Diseases
https://read.qxmd.com/read/25022437/let-the-games-begin-the-race-to-optimise-antibiotic-use
#24
COMMENT
Pranita D Tamma, Sara E Cosgrove
No abstract text is available yet for this article.
August 2014: Lancet Infectious Diseases
https://read.qxmd.com/read/25012226/non-typeable-haemophilus-influenzae-an-under-recognised-pathogen
#25
REVIEW
Johan Van Eldere, Mary P E Slack, Shamez Ladhani, Allan W Cripps
Non-typeable Haemophilus influenzae (NTHi) is a major cause of mucosal infections such as otitis media, sinusitis, conjunctivitis, and exacerbations of chronic obstructive pulmonary disease. In some regions, a strong causal relation links this pathogen with infections of the lower respiratory tract. In the past 20 years, a steady but constant increase has occurred in invasive NTHi worldwide, with perinatal infants, young children, and elderly people most at risk. Individuals with underlying comorbidities are most susceptible and infection is associated with high mortality...
December 2014: Lancet Infectious Diseases
https://read.qxmd.com/read/25008399/tropical-myiases-neglected-and-well-travelled
#26
JOURNAL ARTICLE
John W McGarry
No abstract text is available yet for this article.
August 2014: Lancet Infectious Diseases
https://read.qxmd.com/read/24982316/adenovirus-infections-in-immunocompetent-and-immunocompromised-patients
#27
REVIEW
Thomas Lion
Human adenoviruses (HAdVs) are an important cause of infections in both immunocompetent and immunocompromised individuals, and they continue to provide clinical challenges pertaining to diagnostics and treatment. The growing number of HAdV types identified by genomic analysis, as well as the improved understanding of the sites of viral persistence and reactivation, requires continuous adaptions of diagnostic approaches to facilitate timely detection and monitoring of HAdV infections. In view of the clinical relevance of life-threatening HAdV diseases in the immunocompromised setting, there is an urgent need for highly effective treatment modalities lacking major side effects...
July 2014: Clinical Microbiology Reviews
https://read.qxmd.com/read/23587654/complexity-of-resistance-mechanisms-to-imipenem-in-intensive-care-unit-strains-of-pseudomonas-aeruginosa
#28
JOURNAL ARTICLE
Damien Fournier, Charlotte Richardot, Emeline Müller, Marjorie Robert-Nicoud, Catherine Llanes, Patrick Plésiat, Katy Jeannot
BACKGROUND: Pseudomonas aeruginosa can become resistant to carbapenems by both intrinsic (mutation-driven) and transferable (β-lactamase-based) mechanisms. Knowledge of the prevalence of these various mechanisms is important in intensive care units (ICUs) in order to define optimal prevention and therapeutic strategies. METHODS: A total of 109 imipenem-non-susceptible (MIC >4 mg/L) strains of P. aeruginosa were collected in June 2010 from the ICUs of 26 French public hospitals...
August 2013: Journal of Antimicrobial Chemotherapy
https://read.qxmd.com/read/22354300/in-vivo-pharmacokinetics-pharmacodynamics-of-colistin-and-imipenem-in-pseudomonas-aeruginosa-biofilm-infection
#29
JOURNAL ARTICLE
Wang Hengzhuang, Hong Wu, Oana Ciofu, Zhijun Song, Niels Høiby
Many Pseudomonas aeruginosa isolates from the airways of patients with cystic fibrosis (CF) are sensitive to antibiotics in susceptibility testing, but eradication of the infection is difficult. The main reason is the biofilm formation in the airways of patients with CF. The pharmacokinetics (PKs) and pharmacodynamics (PDs) of antimicrobials can reliably be used to predict whether antimicrobial regimens will achieve the maximum bactericidal effect against infections. Unfortunately, however, most PK/PD studies of antimicrobials have been done on planktonic cells and very few PK/PD studies have been done on biofilms, partly due to the lack of suitable models in vivo...
May 2012: Antimicrobial Agents and Chemotherapy
1
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.