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Neutropenic fever approach

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By Jason Mann No BS pulmonary critical care fellow
Alison G Freifeld, Eric J Bow, Kent A Sepkowitz, Michael J Boeckh, James I Ito, Craig A Mullen, Issam I Raad, Kenneth V Rolston, Jo-Anne H Young, John R Wingard
This document updates and expands the initial Infectious Diseases Society of America (IDSA) Fever and Neutropenia Guideline that was published in 1997 and first updated in 2002. It is intended as a guide for the use of antimicrobial agents in managing patients with cancer who experience chemotherapy-induced fever and neutropenia. Recent advances in antimicrobial drug development and technology, clinical trial results, and extensive clinical experience have informed the approaches and recommendations herein...
February 15, 2011: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Diana Averbuch, Christina Orasch, Catherine Cordonnier, David M Livermore, Malgorzata Mikulska, Claudio Viscoli, Inge C Gyssens, Winfried V Kern, Galina Klyasova, Oscar Marchetti, Dan Engelhard, Murat Akova
Owing to increasing resistance and the limited arsenal of new antibiotics, especially against Gram-negative pathogens, carefully designed antibiotic regimens are obligatory for febrile neutropenic patients, along with effective infection control. The Expert Group of the 4(th) European Conference on Infections in Leukemia has developed guidelines for initial empirical therapy in febrile neutropenic patients, based on: i) the local resistance epidemiology; and ii) the patient's risk factors for resistant bacteria and for a complicated clinical course...
December 2013: Haematologica
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