Xiaowen Yin, Ling Chen, Yong Xia, Qunkang Cheng, Jiabei Yuan, Yan Yang, Zhaoxin Wang, Haojie Wang, Jianshu Dong, Yuqiang Ding, Xudong Zhao
Maternal deprivation (MD) is frequently used as an early life stress model in rodents to investigate behavioral and neurological responses under stressful conditions. However, the effect of MD on the early postnatal development of rodents, which is when multiple neural systems become established, is rarely investigated due to methodological limitations. Ultrasonic vocalizations (USVs) are one of the few responses produced by neonatal rodents that can be quantitatively analyzed, and the quantification of USVs is regarded as a novel approach to investigate possible alterations in the neurobehavioral and emotional development of infant rodents under stress...
2016: PloS One