Use the collections feature with a free QxMD account.
Use Read by QxMD to access full text via your institution or open access sources.
Read also provides personalized recommendations to keep you up to date in your field.
Existing User
Sign InNew to Read
Sign Up#41
JOURNAL ARTICLE
Ying Yang, Wei Sun, Dan Li, Xue-Yuan Li, Xin-Tao Wang, Shu-Chang Li, Hong-Jun Zhao, Jing-Bo Zhang
Atrial fibrillation (AF) is an independent risk factor for intracranial hemorrhage in patients receiving recombinant-tissue-type plasminogen activator (rt-PA) thrombolytic therapy. Research showed that patients with acute ischemic stroke (AIS) could benefit from multimode computed-tomography- (CT-) guided intravenous thrombolysis over 4.5 hours. The medical data of patients with AIS in our center were retrospectively reviewed, and the data of the multimode CT-guided thrombolytic therapy or nonthrombolytic therapy within different time windows (3-9 hours) were evaluated...
July 27, 2019: International Heart Journal
#42
REVIEW
Peter J Hutchinson, Angelos G Kolias, Tamara Tajsic, Amos Adeleye, Abenezer Tirsit Aklilu, Tedy Apriawan, Abdul Hafid Bajamal, Ernest J Barthélemy, B Indira Devi, Dhananjaya Bhat, Diederik Bulters, Randall Chesnut, Giuseppe Citerio, D Jamie Cooper, Marek Czosnyka, Idara Edem, Nasser M F El-Ghandour, Anthony Figaji, Kostas N Fountas, Clare Gallagher, Gregory W J Hawryluk, Corrado Iaccarino, Mathew Joseph, Tariq Khan, Tsegazeab Laeke, Oleg Levchenko, Baiyun Liu, Weiming Liu, Andrew Maas, Geoffrey T Manley, Paul Manson, Anna T Mazzeo, David K Menon, Daniel B Michael, Susanne Muehlschlegel, David O Okonkwo, Kee B Park, Jeffrey V Rosenfeld, Gail Rosseau, Andres M Rubiano, Hamisi K Shabani, Nino Stocchetti, Shelly D Timmons, Ivan Timofeev, Chris Uff, Jamie S Ullman, Alex Valadka, Vicknes Waran, Adam Wells, Mark H Wilson, Franco Servadei
BACKGROUND: Two randomised trials assessing the effectiveness of decompressive craniectomy (DC) following traumatic brain injury (TBI) were published in recent years: DECRA in 2011 and RESCUEicp in 2016. As the results have generated debate amongst clinicians and researchers working in the field of TBI worldwide, it was felt necessary to provide general guidance on the use of DC following TBI and identify areas of ongoing uncertainty via a consensus-based approach. METHODS: The International Consensus Meeting on the Role of Decompressive Craniectomy in the Management of Traumatic Brain Injury took place in Cambridge, UK, on the 28th and 29th September 2017...
July 2019: Acta Neurochirurgica
#43
REVIEW
Milani Deb-Chatterji, Simon Schuster, Vivien Haeussler, Christian Gerloff, Götz Thomalla, Tim Magnus
Primary angiitis of the central nervous system (PACNS) is an inflammatory brain disease affecting the medium and small vessels of the CNS. Although recent data of patients with PACNS have advanced the understanding of the disease, the diagnosis remains challenging. Clinical presentation of PACNS is broad and unspecific and the majority of the diagnostic approaches are hallmarked by a low specificity. Thus, PACNS is commonly misdiagnosed. In addition, due to its potential aggressive course which may be altered by an adequate immunosuppressive treatment, delineation from other vasculopathies and PACNS mimics is crucial...
2019: Frontiers in Neurology
#44
REVIEW
Kenny Li, Christen D Barras, Ronil V Chandra, Hong K Kok, Julian T Maingard, Nicole S Carter, Jeremy H Russell, Leon Lai, Mark Brooks, Hamed Asadi
BACKGROUND: Despite decades of research, cerebral vasospasm (CV) continues to account for high morbidity and mortality in patients who survive their initial aneurysmal subarachnoid hemorrhage. OBJECTIVE: To define the scope of the problem and review key treatment strategies that have shaped the way CV is managed in the contemporary era. METHODS: A literature search was performed of CV management after aneurysmal subarachnoid hemorrhage. RESULTS: Recent advances in neuroimaging have led to improved detection of vasospasm, but established treatment guidelines including hemodynamic augmentation and interventional procedures remain highly variable among neurosurgical centers...
June 2019: World Neurosurgery
#45
REVIEW
Huajun Yang, Wei Shan, Fei Zhu, Jianping Wu, Qun Wang
There is growing evidence that ketone bodies, which are derived from fatty acid oxidation and usually produced in fasting state or on high-fat diets have broad neuroprotective effects. Although the mechanisms underlying the neuroprotective effects of ketone bodies have not yet been fully elucidated, studies in recent years provided abundant shreds of evidence that ketone bodies exert neuroprotective effects through possible mechanisms of anti-oxidative stress, maintaining energy supply, modulating the activity of deacetylation and inflammatory responses...
2019: Frontiers in Neurology
#46
JOURNAL ARTICLE
Victor E Staartjes, Costanza M Zattra, Kevin Akeret, Nicolai Maldaner, Giovanni Muscas, Christiaan Hendrik Bas van Niftrik, Jorn Fierstra, Luca Regli, Carlo Serra
OBJECTIVE: Although rates of postoperative morbidity and mortality have become relatively low in patients undergoing transnasal transsphenoidal surgery (TSS) for pituitary adenoma, cerebrospinal fluid (CSF) fistulas remain a major driver of postoperative morbidity. Persistent CSF fistulas harbor the potential for headache and meningitis. The aim of this study was to investigate whether neural network-based models can reliably identify patients at high risk for intraoperative CSF leakage...
June 21, 2019: Journal of Neurosurgery
#47
JOURNAL ARTICLE
Sarah E Chancellor, Erich S Franz, Olga V Minaeva, Lee E Goldstein
Although concussion has been a subject of interest for centuries, this condition remains poorly understood. The mechanistic underpinnings and accepted definition of concussion remain elusive. To make sense of these issues, this article presents a brief history of concussion studies, detailing the evolution of motivations and experimental conclusions over time. Interest in concussion as a subject of scientific inquiry has increased with growing concern about the long-term consequences of mild traumatic brain injury (TBI)...
July 2019: Seminars in Pediatric Neurology
#48
REVIEW
Jonathan T Carter
Widespread adoption of electronic medical records (EMRs) in the United States is transforming the practice of medicine from a paper-based cottage industry into an integrated health care delivery system. Most physicians and institutions view the widespread use of EMRs to be inevitable. But the transformation has not been painless. Many have questioned whether the substantial investment in electronic health records has really been justified by improved patient outcomes or quality of care. This article describes historical and recent efforts to use EMRs to improve the quality of patient care, and provides a roadmap of EMR uses for the foreseeable future...
April 2015: Neurosurgery Clinics of North America
#49
JOURNAL ARTICLE
Francesco Brigo, Maximilian Schneider, Gudrun Wagenpfeil, Marcus Michael Unger, Claudia Holzhoffer, Silke Walter, Klaus Faßbender, Piergiorgio Lochner
In this retrospective study, we explored the clinical and stroke characteristics of patients treated with thrombolysis and/or mechanical thrombectomy for an acute stroke and experiencing early poststroke seizures within 7 days of the cerebrovascular accident. Patients with prior epilepsy, primary intracerebral hemorrhage or transient ischemic attacks, or taking antiepileptic drugs were excluded. We retrospectively identified 32 patients admitted between 2010 and 2016 (mean age 75 years; range: 49-90; 14 females and 18 males)...
March 2020: Epilepsy & Behavior: E&B
#50
JOURNAL ARTICLE
Ying Guo, Shiming Fang, Jin Wang, Chen Wang, Jianguo Zhao, Yingnan Gai
Objective: Delayed cerebral ischemia (DCI) and seizures are dreaded neurological complications following aneurysmal subarachnoid hemorrhage (SAH). They may lead to severe mortality or mobility. Continuous electroencephalography (cEEG) is quite useful for secondary brain injury monitoring. This study aims to assess the effectiveness and sensitivity of cEEG in detecting DCI and seizures. Methods: Reports published up to July 31, 2018 were retrieved from PubMed, Medline, Cochrane and EMABSE. A systematic review was carried out on eligible studies...
October 2020: British Journal of Neurosurgery
#51
JOURNAL ARTICLE
Jay L Koyner, Kyle A Carey, Dana P Edelson, Matthew M Churpek
OBJECTIVES: To develop an acute kidney injury risk prediction model using electronic health record data for longitudinal use in hospitalized patients. DESIGN: Observational cohort study. SETTING: Tertiary, urban, academic medical center from November 2008 to January 2016. PATIENTS: All adult inpatients without pre-existing renal failure at admission, defined as first serum creatinine greater than or equal to 3.0 mg/dL, International Classification of Diseases, 9th Edition, code for chronic kidney disease stage 4 or higher or having received renal replacement therapy within 48 hours of first serum creatinine measurement...
July 2018: Critical Care Medicine
#52
JOURNAL ARTICLE
Danton S Char, Nigam H Shah, David Magnus
The incorporation of machine learning into clinical medicine holds promise for substantially improving health care delivery. Private companies are rushing to build machine learning into medical decision making, pursuing both tools that support physicians and algorithms designed to function..
March 15, 2018: New England Journal of Medicine
#53
REVIEW
Roxana Mehran, George D Dangas, Steven D Weisbord
New England Journal of Medicine, Volume 380, Issue 22, Page 2146-2155, May 2019.
May 30, 2019: New England Journal of Medicine
#54
REVIEW
Juan Carlos Martinez-Gutierrez, Ronil V Chandra, Joshua A Hirsch, Thabele Leslie-Mazwi
BACKGROUND: With the benefit of mechanical thrombectomy firmly established, the focus has shifted to improved delivery of care. Reducing time from symptom onset to reperfusion is a primary goal. Technology promises tremendous opportunities in the prehospital space to achieve this goal. METHODS: This review explores existing, fledgling, and potential future technologies for application in the prehospital space. RESULTS: The opportunity for technology to improve stroke care resides in the detection, evaluation, triage, and transport of patients to an appropriate healthcare facility...
November 2019: Journal of Neurointerventional Surgery
#55
JOURNAL ARTICLE
Min Hwan Lee, Joong-Goo Kim, Sang Bum Jeon, Dong-Wha Kang, Sun U Kwon, Jong S Kim
No abstract text is available yet for this article.
May 2019: Journal of Stroke
#56
JOURNAL ARTICLE
Ching-Jen Chen, Dale Ding, Natasha Ironside, Thomas J Buell, Andrew M Southerland, Fernando D Testai, Daniel Woo, Bradford B Worrall
OBJECTIVE: The utility of ICP monitoring and its benefit with respect to outcomes after ICH is unknown. The aim of this study was to compare intracerebral hemorrhage (ICH) outcomes in patients who underwent intracranial pressure (ICP) monitoring to those who were managed by care-guided imaging and/or clinical examination alone. METHODS: This was a retrospective analysis of data from the Ethnic/Racial variations of Intracerebral Hemorrhage (ERICH) study between 2010 and 2015...
May 31, 2019: Journal of Neurosurgery
#57
JOURNAL ARTICLE
Syed Ijlal Ahmed, Gohar Javed, Syeda Beenish Bareeqa, Syeda Sana Samar, Ali Shah, Arwa Giani, Zainab Aziz, Abeer Tasleem, Syed Hasham Humayun
Background Aneurysmal subarachnoid hemorrhage is a frequently devastating condition with a reported incidence of between 10 and 15 people per 100,000 in the United States. Currently, according to the best of our knowledge, there are not enough meta-analyses available in the medical literature of the last five years which compare the risks and benefits of endovascular coiling with neurosurgical clipping. Methods Twenty-two studies were selected out of the short-listed studies. The studies were selected on the basis of relevance to the topic, sample size, sampling technique, and randomization...
March 26, 2019: Curēus
#58
REVIEW
Isabel C Hostettler, David J Seiffge, David J Werring
Introduction : Spontaneous non-traumatic intracerebral hemorrhage (ICH) is most often caused by small vessel diseases: deep perforator arteriopathy (hypertensive arteriopathy) or cerebral amyloid angiopathy (CAA). Although ICH accounts for only 10-15% of all strokes it causes a high proportion of stroke mortality and morbidity, with few proven effective acute or preventive treatments. Areas covered : We conducted a literature search on etiology, diagnosis, treatment, management and current clinical trials in ICH...
July 2019: Expert Review of Neurotherapeutics
#59
JOURNAL ARTICLE
Kimberly P Kicielinski, Christopher S Ogilvy
As ischemic stroke care advances with more patients eligible for mechanical thrombectomy, so too does the role of the neurosurgeon in these patients. Neurosurgeons are an important member of the team from triage through the intensive care unit. This paper explores current research and insights on the contributions of neurosurgeons in care of acute ischemic stroke patients in the acute setting.
July 1, 2019: Neurosurgery
#60
JOURNAL ARTICLE
Robert C Rennert, Arvin R Wali, Jeffrey A Steinberg, David R Santiago-Dieppa, Scott E Olson, J Scott Pannell, Alexander A Khalessi
Large vessel occlusions (LVOs), variably defined as blockages of the proximal intracranial anterior and posterior circulation, account for approximately 24% to 46% of acute ischemic strokes. Commonly refractory to intravenous tissue plasminogen activator (tPA), LVOs place large cerebral territories at ischemic risk and cause high rates of morbidity and mortality without further treatment. Over the past few years, an abundance of high-quality data has demonstrated the efficacy of endovascular thrombectomy for improving clinical outcomes in patients with LVOs, transforming the treatment algorithm for affected patients...
July 1, 2019: Neurosurgery
Make the most of Read.
Download the mobile app.
Download the mobile app.
Fetching more papers... 
