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Angela Dispenzieri, A Keith Stewart, Asher Chanan-Khan, S Vincent Rajkumar, Robert A Kyle, Rafael Fonseca, Prashant Kapoor, P Leif Bergsagel, Arleigh McCurdy, Morie A Gertz, Martha Q Lacy, John A Lust, Stephen J Russell, Steven R Zeldenrust, Craig Reeder, Vivek Roy, Francis Buadi, David Dingli, Suzanne R Hayman, Nelson Leung, Yi Lin, Joseph Mikhael, Shaji K Kumar
Smoldering multiple myeloma (SMM) bridges the gap between monoclonal gammopathy of undetermined significance (a mostly premalignant disorder) and active multiple myeloma (MM). Until recently, no interventional study in patients with SMM showed improved overall survival (OS) with therapy as compared with observation. A report from the PETHEMA-GEM (Programa Español de Tratamientos en Hematologica) group described both fewer myeloma-related events and better OS among patients with high-risk SMM who were treated with lenalidomide and dexamethasone...
December 19, 2013: Blood
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