Kellie Wang, Ruben Santiago
INTRODUCTION: Over the last decade, tranexamic acid (TXA) has been incorporated into treatment algorithms for a multitude of emergent conditions and the evidence surrounding its role in emergency medicine continues to evolve. OBJECTIVE: The objective of this literature review is to provide an evidence-based approach to the utilization of TXA in the emergency department. DISCUSSION: The most robust trials suggest TXA may offer a modest improvement in mortality in patients at risk of significant bleeding from trauma, but is not beneficial in spontaneous intracranial hemorrhage or gastrointestinal bleeding...
June 2022: American Journal of Emergency Medicine