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Maurizio Martelli, Andrés J M Ferreri, Claudio Agostinelli, Alice Di Rocco, Michael Pfreundschuh, Stefano A Pileri
Diffuse large B-cell lymphoma (DLBCL) is the most common lymphoid malignancy in adults accounting for 31% of all NHL in Western Countries. Following, morphological, biological and clinical studies have allowed the subdivision of DLBCLs into morphological variants, molecular and immunophenotypic subgroups and distinct disease entities. However, a large number of cases still remain biologically and clinically heterogeneous, for which there are no clear and accepted criteria for subclassification; these are collectively termed DLBCL, not otherwise specified (NOS)...
August 2013: Critical Reviews in Oncology/hematology
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