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https://read.qxmd.com/read/33626481/euglycemic-diabetic-ketoacidosis-etiologies-evaluation-and-management
#1
REVIEW
Brit Long, Skyler Lentz, Alex Koyfman, Michael Gottlieb
INTRODUCTION: Diabetic ketoacidosis is an endocrine emergency. A subset of diabetic patients may present with relative euglycemia with acidosis, known as euglycemic diabetic ketoacidosis (EDKA), which is often misdiagnosed due to a serum glucose <250 mg/dL. OBJECTIVE: This narrative review evaluates the pathogenesis, diagnosis, and management of EDKA for emergency clinicians. DISCUSSION: EDKA is comprised of serum glucose <250 mg/dL with an anion gap metabolic acidosis and ketosis...
June 2021: American Journal of Emergency Medicine
https://read.qxmd.com/read/26078479/euglycemic-diabetic-ketoacidosis-a-potential-complication-of-treatment-with-sodium-glucose-cotransporter-2-inhibition
#2
Anne L Peters, Elizabeth O Buschur, John B Buse, Pejman Cohan, Jamie C Diner, Irl B Hirsch
OBJECTIVE: Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are the most recently approved antihyperglycemic medications. We sought to describe their association with euglycemic diabetic ketoacidosis (euDKA) in hopes that it will enhance recognition of this potentially life-threatening complication. RESEARCH DESIGN AND METHODS: Cases identified incidentally are described. RESULTS: We identified 13 episodes of SGLT-2 inhibitor-associated euDKA or ketosis in nine individuals, seven with type 1 diabetes and two with type 2 diabetes, from various practices across the U...
September 2015: Diabetes Care
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