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By Andrew Buelt Questioningmedicine, intern in residency
Malana Moshesh, Andrew F Olshan, Tina Saldana, Donna Baird
INTRODUCTION: Despite estimates of a high prevalence of deep dyspareunia (DD) among women in the United States, risk factors for this important area of sexual dysfunction have been largely understudied. AIMS: The purpose of this study was to examine the relationship between uterine fibroids and the prevalence of DD. METHODS: We used data from the Uterine Fibroid Study (enrollment 1996-1999 in a U.S. metropolitan area). Participating women were ages 35-49 and were randomly selected from the membership rolls of a prepaid health plan...
March 2014: Journal of Sexual Medicine
Sereina A Herzog, Janneke C M Heijne, Pippa Scott, Christian L Althaus, Nicola Low
BACKGROUND: Pelvic inflammatory disease (PID) results from the ascending spread of microorganisms, including Chlamydia trachomatis, to the upper genital tract. Screening could improve outcomes by identifying and treating chlamydial infections before they progress to PID (direct effect) or by reducing chlamydia transmission (indirect effect). METHODS: We developed a compartmental model that represents a hypothetical heterosexual population and explicitly incorporates progression from chlamydia to clinical PID...
November 2013: Epidemiology
Sarah A Schoeman, Catherine M W Stewart, Russell A Booth, Susan D Smith, Mark H Wilcox, Janet D Wilson
OBJECTIVE: To compare vulvovaginal swabs with endocervical swabs as optimal diagnostic sample for detection of Chlamydia trachomatis infection. DESIGN: A diagnostic test study. SETTING: An urban sexual health centre. PARTICIPANTS: 3973 women aged ≥ 16 years requesting testing for sexually transmitted infections. INTERVENTIONS: Participants took a vulvovaginal swab before routine examination, and clinicians took an endocervical swab during examination...
December 12, 2012: BMJ: British Medical Journal
Saundra S Buys, Edward Partridge, Amanda Black, Christine C Johnson, Lois Lamerato, Claudine Isaacs, Douglas J Reding, Robert T Greenlee, Lance A Yokochi, Bruce Kessel, E David Crawford, Timothy R Church, Gerald L Andriole, Joel L Weissfeld, Mona N Fouad, David Chia, Barbara O'Brien, Lawrence R Ragard, Jonathan D Clapp, Joshua M Rathmell, Thomas L Riley, Patricia Hartge, Paul F Pinsky, Claire S Zhu, Grant Izmirlian, Barnett S Kramer, Anthony B Miller, Jian-Lun Xu, Philip C Prorok, John K Gohagan, Christine D Berg
CONTEXT: Screening for ovarian cancer with cancer antigen 125 (CA-125) and transvaginal ultrasound has an unknown effect on mortality. OBJECTIVE: To evaluate the effect of screening for ovarian cancer on mortality in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. DESIGN, SETTING, AND PARTICIPANTS: Randomized controlled trial of 78,216 women aged 55 to 74 years assigned to undergo either annual screening (n = 39,105) or usual care (n = 39,111) at 10 screening centers across the United States between November 1993 and July 2001...
June 8, 2011: JAMA: the Journal of the American Medical Association
Jillian T Henderson, George F Sawaya, Maya Blum, Laura Stratton, Cynthia C Harper
OBJECTIVE: Requiring a pelvic examination before prescribing oral contraception poses an unnecessary barrier to contraceptive access. Medical guidelines have outlined the safety of oral contraception provision without a pelvic examination, yet little is known about the practices of clinicians providing reproductive health care. Our purpose was to investigate clinicians' requirements for pelvic examination and what may account for practice differences. METHODS: We administered a mailed survey to a national probability sample of obstetrician-gynecologists (ob-gyns), family medicine physicians, and advanced practice nurses specializing in obstetrics and gynecology and women's health or family medicine in 2008-2009 (N=1,196), with a response rate of 65...
December 2010: Obstetrics and Gynecology
David S Meyers, Heather Halvorson, Sara Luckhaupt
BACKGROUND: Chlamydial infection is the most common sexually transmitted bacterial infection in the United States, with an estimated 3 million new cases annually. In 2001, the U.S. Preventive Services Task Force (USPSTF) recommended that clinicians screen all sexually active women at increased risk for infection for Chlamydia trachomatis. PURPOSE: To summarize a systematic evidence review commissioned by the USPSTF in preparation for an update of its 2001 recommendation...
July 17, 2007: Annals of Internal Medicine
G L Adonakis, E Paraskevaidis, S Tsiga, K Seferiadis, D E Lolis
The purpose of this study was to investigate the effectiveness of the combined procedure including pelvic examination and serum CA-125 determination, as a screening method for the early detection of ovarian cancer. In 2000 women over 45 years old, without any evidence of adnexal disease, pelvic examination and serum CA-125 determination were performed. When either the findings of the pelvic examination were ambiguous or positive, or the serum CA-125 level was > 35 U/ml, further investigation including ultrasonography and laparoscopy or laparotomy was done...
April 1996: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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