Rima McLeod, Kenneth Boyer, Theodore Karrison, Kristen Kasza, Charles Swisher, Nancy Roizen, Jessica Jalbrzikowski, Jack Remington, Peter Heydemann, A Gwendolyn Noble, Marilyn Mets, Ellen Holfels, Shawn Withers, Paul Latkany, Paul Meier
BACKGROUND: Without treatment, congenital toxoplasmosis has recurrent, recrudescent, adverse outcomes. Long-term follow-up of infants with congenital toxoplasmosis treated throughout their first year of life with pyrimethamine and sulfadiazine has not been reported. METHODS: Between 1981 and 2004, one hundred twenty infants (current mean age +/- standard deviation, 10.5 +/- 4.8 years) with congenital toxoplasmosis were treated with 1 of 2 doses of pyrimethamine plus sulfadiazine; therapy was initiated shortly after birth and continued for 12 months...
May 15, 2006: Clinical Infectious Diseases