Caroline Gross Dutra, Lucas Rosa Fraga, Andréa Prestes Nácul, Eduardo Pandolfi Passos, Rozana Oliveira Gonçalves, Olívia Lucia Nunes, Bibiane Armiliato De Godoy, Sandra Leistner-Segal, Fernanda Sales Luiz Vianna, Lavínia Schüler-Faccini, Maria Teresa Vieira Sanseverino
Recurrent pregnancy loss (RPL) is defined as the occurrence of two or more consecutive pregnancy losses. It is an important reproductive condition with a complex etiology. In approximately 50% of RPL cases an explanation for the cause is not found and they are therefore classified as idiopathic RPL. One of the causes implicated in RPL is thrombophilia, which consists of hemostatic disorders that lead to an increase in thromboembolic processes. The aim of this study was to evaluate polymorphic variants in genes related to thrombophilia as a risk factor in women with RPL...
June 2014: Human Fertility: Journal of the British Fertility Society