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Liver surgery

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78 papers 100 to 500 followers
By Giovanni Gambino M.D. Ph.D.
Per Sandström, Bård I Røsok, Ernesto Sparrelid, Peter N Larsen, Anna L Larsson, Gert Lindell, Nicolai A Schultz, Bjorn A Bjørnbeth, Bengt Isaksson, Magnus Rizell, Bergthor Björnsson
OBJECTIVE: The aim of the study was to evaluate if associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) could increase resection rates (RRs) compared with two-stage hepatectomy (TSH) in a randomized controlled trial (RCT). BACKGROUND: Radical liver metastasis resection offers the only chance of a cure for patients with metastatic colorectal cancer. Patients with colorectal liver metastasis (CRLM) and an insufficient future liver remnant (FLR) volume are traditionally treated with chemotherapy with portal vein embolization or ligation followed by hepatectomy (TSH)...
May 2018: Annals of Surgery
Masaki Kaibori, Kengo Yoshii, Isao Yokota, Kiyoshi Hasegawa, Fumio Nagashima, Shoji Kubo, Masanori Kon, Namiki Izumi, Masumi Kadoya, Masatoshi Kudo, Takashi Kumada, Michiie Sakamoto, Osamu Nakashima, Yutaka Matsuyama, Tadatoshi Takayama, Norihiro Kokudo
OBJECTIVE: The impact of age on survival after hepatic resection for hepatocellular carcinoma (HCC) has not been thoroughly examined. We reviewed the data of a nationwide follow-up survey to determine the outcomes of hepatectomy for HCC in elderly patients. BACKGROUND: Management of malignant diseases in elderly patients has become a global clinical issue because of the increased life expectancy worldwide. Advancements in surgical techniques and perioperative management have reduced age-related contraindications for liver surgery...
September 15, 2017: Annals of Surgery
Glenn K Bonney, Chris Coldham, Rene Adam, Gernot Kaiser, Eduardo Barroso, Lorenzo Capussotti, Christophe Laurent, Cees Verhoef, Gennaro Nuzzo, Dominique Elias, Real Lapointe, Catherine Hubert, Santiago Lopez-Ben, Marek Krawczyk, Darius F Mirza
BACKGROUND AND OBJECTIVES: The use of neo-adjuvant chemotherapy in resectable synchronous liver metastasis is ill defined. The aim of this study was to evaluate neo-adjuvant chemotherapy on outcomes following liver resection for synchronous CLM. METHODS: An analysis of a multi-centric cohort from the LiverMetSurvey International Registry, who had undergone curative resections for synchronous CLM was undertaken. Patients who received neo-adjuvant chemotherapy prior to liver surgery (group NAS; n = 693) were compared with those treated by surgery alone (group SG; n = 608)...
May 2015: Journal of Surgical Oncology
F Cauchy, D Fuks, T Nomi, L Schwarz, L Barbier, S Dokmak, O Scatton, J Belghiti, O Soubrane, B Gayet
BACKGROUND: Although recent reports have suggested potential benefits of the laparoscopic approach in patients requiring major hepatectomy, it remains unclear whether conversion to open surgery could offset these advantages. This study aimed to determine the risk factors for and postoperative consequences of conversion in patients undergoing laparoscopic major hepatectomy (LMH). METHODS: Data for all patients undergoing LMH between 2000 and 2013 at two tertiary referral centres were reviewed retrospectively...
June 2015: British Journal of Surgery
S Marubashi, K Gotoh, H Akita, H Takahashi, Y Ito, M Yano, O Ishikawa, M Sakon
BACKGROUND: The optimal surgical resection method in patients with HCC to minimize the risk of local recurrence has not yet been determined. The aim of this study was to compare the prognosis following anatomical versus non-anatomical hepatic resection for hepatocellular carcinoma (HCC). METHODS: Consecutive patients with HCC without macroscopic vascular invasion, treated by curative resection between 1981 and 2012 at Osaka Medical Centre, were included in this retrospective study...
June 2015: British Journal of Surgery
Satoshi Ogiso, Claudius Conrad, Kenichiro Araki, Takeo Nomi, Zeynal Anil, Brice Gayet
OBJECTIVE: We describe the technical details and evaluate the safety, feasibility, and usefulness of a combined lateral and abdominal (CLA) approach for laparoscopic resection of liver segments 7 and 8. BACKGROUND: Laparoscopic resection of lesions in the posterosuperior area of segments 7 and 8 is technically challenging, and currently there is no standardized laparoscopic approach. METHODS: Through review of a prospectively maintained database, we identified 44 patients who underwent laparoscopic resection of lesions in segment 7 or 8...
August 2015: Annals of Surgery
Yasushi Hasegawa, Hiroyuki Nitta, Akira Sasaki, Takeshi Takahara, Hidenori Itabashi, Hirokatsu Katagiri, Koki Otsuka, Satoshi Nishizuka, Go Wakabayashi
BACKGROUND: Laparoscopic liver resection for liver metastases from colorectal cancer (CRLM) is performed in a relatively small number of institutions. Its operative results have been reported to be comparable with that of open laparotomy; however, information on its oncologic outcomes is scarce. This study aimed to compare the long-term outcomes of laparoscopic hepatectomy (LH) and open hepatectomy (OH) to treat CRLM at a single institution. METHODS: We retrospectively reviewed data from 168 consecutive patients who underwent LH (n = 100) or OH (n = 68) for CRLM...
June 2015: Surgery
Po-Hong Liu, Chia-Yang Hsu, Cheng-Yuan Hsia, Yun-Hsuan Lee, Yi-Hsiang Huang, Yi-You Chiou, Han-Chieh Lin, Teh-Ia Huo
OBJECTIVES: To evaluate the efficacy of surgical resection (SR) and radiofrequency ablation (RFA) for single hepatocellular carcinoma (HCC) 2  cm or less. BACKGROUND: The optimal management for Barcelona Clínic Liver Cancer (BCLC) very early-stage HCC is undetermined. METHODS: Between 2002 and 2013, a total of 237 (SR, 109; RFA, 128) patients with BCLC very early-stage HCC were enrolled. Their overall survival (OS) and recurrence-free survival (RFS) were compared...
March 2016: Annals of Surgery
Yoshihiro Mise, Thomas A Aloia, Kristoffer W Brudvik, Lilian Schwarz, Jean-Nicolas Vauthey, Claudius Conrad
OBJECTIVE: To investigate prognostic impact of parenchymal-sparing hepatectomy (PSH) for solitary small colorectal liver metastasis (CLM). BACKGROUND: It is unclear whether PSH confers an oncologic benefit through increased salvageability or is a detriment through increasing recurrence rate. METHODS: Database of 300 CLM patients with a solitary tumor (≤ 30 mm in size) was reviewed from 1993 to 2013. A total of 156 patients underwent PSH and 144 patients underwent right hepatectomy, left hepatectomy, or left lateral sectionectomy (non-PSH group)...
January 2016: Annals of Surgery
Yuan-da Zhou, Hui-kai Li, Yun-long Cui, Ti Zhang, Qiang Li
AIMS: This study was conducted in order to investigate the indications for hepatecomy for multinodular hepatocellular carcinoma (MNHCC) in single institution. METHODS: We retrospectively analyzed the medical records from 55 MNHCC patients, mainly with Child-Pugh A liver function, who underwent hepatectomy from January 2006 to December 2008. Both short- and long-term outcomes were analyzed. In addition, the prognostic significance of clinicopathological factors on overall survival (OS) was investigated by univariate analysis using the log-rank test...
2015: Digestive Surgery
Shin-Ichiro Kobayashi, Tsuyoshi Igami, Tomoki Ebata, Yukihiro Yokoyama, Gen Sugawara, Takashi Mizuno, Yuji Nimura, Masato Nagino
Intrahepatic cholangiocarcinoma involving all major hepatic veins was diagnosed in a 62-year-old man. Multidetector-row computed tomography showed a massive tumor occupying segments 2-5, 7, and 8, with invasion of all major hepatic veins, although the inferior right hepatic vein, draining the venous flow of segment 6, was clearly visualized. Therefore, we planned an extended left trisectionectomy, involving resection of segments 1-5, 7, and 8, with extrahepatic bile duct resection and concomitant resection of all major hepatic veins...
August 2015: Surgery Today
David Fuks, François Cauchy, Samir Ftériche, Takeo Nomi, Lilian Schwarz, Safi Dokmak, Olivier Scatton, Grazia Fusco, Jacques Belghiti, Brice Gayet, Olivier Soubrane
OBJECTIVE: To compare both incidence and types of postoperative pulmonary complications (PPCs) between laparoscopic major hepatectomy (LMH) and open major hepatectomy (OMH). BACKGROUND: LMHs are increasingly performed. Yet, the benefits of laparoscopy over laparotomy regarding PPCs remain unknown. METHODS: In this multi-institutional study, all patients undergoing OMH or LMH between 1998 and 2013 were retrospectively reviewed. Risk factors for PPCs were analyzed on multivariate analysis...
February 2016: Annals of Surgery
Gerd R Silberhumer, Philip B Paty, Larissa K Temple, Raphael L C Araujo, Brian Denton, Mithat Gonen, Garret M Nash, Peter J Allen, Ronald P DeMatteo, Jose Guillem, Martin R Weiser, Michael I D'Angelica, William R Jarnagin, Douglas W Wong, Yuman Fong
BACKGROUND: One quarter of colorectal cancer patients will present with liver metastasis at the time of diagnosis. Recent studies have shown that simultaneous resections are safe and feasible for stage IV colon cancer. Limited data are available for simultaneous surgery in stage IV rectal cancer patients. METHODS: One hundred ninety-eight patients underwent surgical treatment for stage IV rectal cancer. In 145 (73%) patients, a simultaneous procedure was performed...
June 2015: American Journal of Surgery
Manel Limeme, Sana Yahyaoui, Houneida Zaghouani, Mosaab Ghannouchi, Abdelmajid Khnissi, Habib Amara, Rached Letaief, Dejla Bakir, Chakib Kraiem
BACKGROUND: Hydatid disease is endemic in certain areas of the world and it is located mostly in the liver. Intraperitoneal rupture is rare. Rupture may result from trauma or may occur spontaneously from increased pressure of the cystic fluid. Ruptured hydatid cyst is a rare cause of ascites, but should be considered in the differential diagnosis, especially in endemic areas. The diagnosis of ruptured hydatid cyst should be prompt because it requires emergency intervention. CASE PRESENTATION: The present case refers to a 62 year old Tunisian male admitted in our institution for diffuse abdominal distension...
November 26, 2014: BMC Surgery
Myron E Schwartz, Charles M Miller, Sasan Roayaie, Ilias P Gomatos, Manousos M Konstadoulakis
AIM: We hereby present and evaluate a technique for hepatic parenchymal transection based on the application of Metzenbaum scissors and clips during liver ischemia. METHODS: Our technique was retrospectively evaluated in 32 noncirrhotic, noncholestatic patients with intrahepatic cholangiocarcinoma and 32 patients with hepatocellular carcinoma (23 of whom cirrhotic, 71.9%). Patient data were retrieved from our Hepatobiliary Surgery Database. Type and duration of vascular clamping, blood transfusion requirements, marginal status and immediate postoperative complications were analyzed...
2014: Digestive Surgery
Suzanne C Schiffman, Kevin H Kim, Allan Tsung, J Wallis Marsh, David A Geller
BACKGROUND: Laparoscopic liver resection (LLR) for metastatic colorectal cancer (mCRC) remains controversial. The objective of this manuscript was to perform a metaanalysis comparing outcomes of LLR with open liver resection (OLR) in patients with hepatic mCRC, and to identify which patients were suitable candidates for LLR. STUDY DESIGN: A PubMed search identified 2,122 articles. When filtered for case-matched articles comparing LLR with OLR for mCRC, 8 articles were identified consisting of 610 patients (242 LLR, 368 OLR)...
February 2015: Surgery
C Riediger, M W Mueller, A Hapfelmeier, J Bachmann, H Friess, J Kleeff
BACKGROUND AND AIMS: In spite of huge developments in liver surgery during the last decades, morbidity and mortality continue to pose problems in this field. The aim of this study was to identify preoperative predictors for postoperative mortality and morbidity in liver surgery. MATERIAL AND METHODS: In a single-center study, an extensive analysis of a prospective database, including clinical criteria and laboratory tests of patients undergoing liver surgery between July 2007 and July 2012 was performed...
September 2015: Scandinavian Journal of Surgery: SJS
Shigenori Ei, Taizo Hibi, Minoru Tanabe, Osamu Itano, Masahiro Shinoda, Minoru Kitago, Yuta Abe, Hiroshi Yagi, Koji Okabayashi, Daisuke Sugiyama, Go Wakabayashi, Yuko Kitagawa
BACKGROUND: Although cryoablation (Cryo) has been advocated as an effective locoregional therapy for hepatocellular carcinoma (HCC), few studies have compared the outcomes with those of radiofrequency ablation (RFA) and microwave coagulation therapy (MCT). METHODS: Consecutive patients with primary HCCs of <5 cm received Cryo or RFA/MCT between 1998 and 2011 and were monitored for local recurrence (defined as a recurrent tumor at or in direct contact with the ablated area) and overall complication rates...
April 2015: Annals of Surgical Oncology
Takeo Nomi, David Fuks, Aditya Agrawal, Mahendran Govindasamy, Kenichiro Araki, Brice Gayet
BACKGROUND: The Pringle maneuver is widely used in liver surgery to reduce intraoperative blood loss. However, total vascular inflow occlusion is frequently associated with ischemia reperfusion injury leading to postoperative liver dysfunction and impaired recovery. We describe herein an original procedure of modified Pringle maneuver (MPM) during laparoscopic liver resection with selective clamping of hepatic arterial inflow. METHODS: Of 183 laparoscopic major hepatectomies performed at the Institute Mutualiste Montsouris between January 1998 and March 2014, 19 patients required vascular clamping, and MPM was used in 6 patients...
March 2015: Annals of Surgical Oncology
Vishal G Shelat, Federica Cipriani, Tiago Basseres, Thomas H Armstrong, Arjun S Takhar, Neil W Pearce, Mohammad AbuHilal
BACKGROUND: Laparoscopic liver resection (LLR) for large malignant tumors can be technically challenging. Data on this topic are scarce, and many question its feasibility, safety, and oncologic efficiency. This study aimed to assess outcomes of LLR for large (≥ 5 cm) and giant (≥ 10 cm) malignant liver tumors. METHODS: A prospectively collected database of 422 LLRs was reviewed from August 2003 to August 2013. The data for 52 patients undergoing LLR for large malignant tumors were analyzed...
April 2015: Annals of Surgical Oncology
2014-09-28 09:41:01
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