Hsin-Chieh Yeh, John P Bantle, Maria Cassidy-Begay, George Blackburn, George A Bray, Tim Byers, Jeanne M Clark, Mace Coday, Caitlin Egan, Mark A Espeland, John P Foreyt, Katelyn Garcia, Valerie Goldman, Edward W Gregg, Helen P Hazuda, Louise Hesson, James O Hill, Edward S Horton, John M Jakicic, Robert W Jeffery, Karen C Johnson, Steven E Kahn, William C Knowler, Mary Korytkowski, Anne Kure, Cora E Lewis, Christos Mantzoros, Maria Meacham, Maria G Montez, David M Nathan, Nicholas Pajewski, Jennifer Patricio, Anne Peters, F Xavier Pi-Sunyer, Henry Pownall, Donna H Ryan, Monika Safford, Rebecca L Sedjo, Helmut Steinburg, Mara Vitolins, Thomas A Wadden, Lynne E Wagenknecht, Rena R Wing, Antonio C Wolff, Holly Wyatt, Susan Z Yanovski
OBJECTIVE: This study was designed to determine whether intensive lifestyle intervention (ILI) aimed at weight loss lowers cancer incidence and mortality. METHODS: Data from the Look AHEAD trial were examined to investigate whether participants randomized to ILI designed for weight loss would have reduced overall cancer incidence, obesity-related cancer incidence, and cancer mortality, as compared with the diabetes support and education (DSE) comparison group. This analysis included 4,859 participants without a cancer diagnosis at baseline except for nonmelanoma skin cancer...
September 2020: Obesity