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By Jose Roled ...
Lu Wang, Howard D Sesso, Robert J Glynn, William G Christen, Vadim Bubes, JoAnn E Manson, Julie E Buring, J Michael Gaziano
BACKGROUND: Recent posttrial analysis of a completed randomized trial found an increased risk of prostate cancer among healthy men taking high-dose vitamin E supplements. Trials that examined the effect of vitamin C supplements on cancer risk are few. OBJECTIVE: We examined whether vitamin E or vitamin C supplementation affects the risk of cancer events during posttrial follow-up of the Physicians' Health Study II. DESIGN: Beginning in 1997, a total of 14,641 US male physicians aged ≥50 y were randomly assigned to receive 400 IU of vitamin E every other day, 500 mg of vitamin C daily, or their respective placebos...
September 2014: American Journal of Clinical Nutrition
Efthalia Kerasioti, Dimitrios Stagos, Alexandros Priftis, Stefanos Aivazidis, Aristidis M Tsatsakis, A Wallace Hayes, Demetrios Kouretas
In the present study, the in vitro scavenging activity of sheep whey protein against free radicals, as well as its reducing power were determined and compared with that of beef protein, soy protein and cow whey protein. Moreover, the possible protective effects of sheep whey protein from tert-butyl hydroperoxide (tBHP)-induced oxidative stress in muscle C2C12 cells were determined by assessing oxidative stress markers by flow cytometry and spectrophotometry. The results showed that sheep whey protein scavenged DPPH, ABTS(+) and OH radicals with IC50 values of 3...
July 15, 2014: Food Chemistry
Nerys M Astbury, Moira A Taylor, Stephen J French, Ian A Macdonald
BACKGROUND: The manipulation of the composition of foods consumed as between-meal snacks may aid daily energy restriction. OBJECTIVES: We compared the effects of the consumption of 2 energy-matched snack bars on appetite, energy intake (EI), and metabolic and endocrine responses. In addition, we investigated whether the acute effects of the consumption of snacks were maintained under free-living conditions and whether the habitual daily consumption of the snack over 14 d influenced these effects...
May 2014: American Journal of Clinical Nutrition
Jan Stanstrup, Simon S Schou, Jens Holmer-Jensen, Kjeld Hermansen, Lars O Dragsted
Whey protein has been demonstrated to improve fasting lipid and insulin response in overweight and obese individuals. To establish new hypotheses for this effect and to investigate the impact of stomach emptying, we compared plasma profiles after intake of whey isolate (WI), casein, gluten (GLU), and cod (COD). Obese, nondiabetic subjects were included in the randomized, blinded, crossover meal study. Subjects ingested a high fat meal containing one of the four protein sources. Plasma samples were collected at five time points and metabolites analyzed using LC-Q-TOF-MS...
May 2, 2014: Journal of Proteome Research
Adam Ambroziak, Grazyna Cichosz
Milk proteins are characterized by the highest immune stimulative potency from among all the proteins present in human diet. Whey proteins and numerous growth factors that regulate insulin secretion, differentiation of intestine epithelium cells, and also tissue restoration, are priceless in stimulation the immune system. Lactoferrin shows the most comprehensive pro-health properties: antioxidative, anticancer, immune stimulative and even chemopreventive. Also peptides and amino acids formed from casein and whey proteins possess immune stimulative activity...
February 2014: Polski Merkuriusz Lekarski: Organ Polskiego Towarzystwa Lekarskiego
S Pal, S Radavelli-Bagatini, M Hagger, V Ellis
BACKGROUND/OBJECTIVE: Dairy protein seems to reduce appetite by increasing satiety and delaying the return of hunger and subsequently lowering energy intake compared with fat or carbohydrate. The aim of this study was to compare the effect of whey with that of casein proteins on satiety in overweight/obese individuals. METHODS/SUBJECTS: This was a randomized, parallel-design 12-week-long study. Seventy subjects with a body mass index between 25 and 40 kg/m(2) and aged 18-65 years were randomized into one of three supplement groups: glucose control (n=25), casein (n=20) or whey (n=25) protein...
September 2014: European Journal of Clinical Nutrition
Amber W Kinsey, Wyatt R Eddy, Takudzwa A Madzima, Lynn B Panton, Paul J Arciero, Jeong-Su Kim, Michael J Ormsbee
The present study investigated whether whey (WH) protein, casein (CAS) protein or a carbohydrate placebo (PLA) consumed 30 min before sleep could acutely alter appetite or cardiometabolic risk the following morning. A total of forty-four sedentary overweight and obese women (BMI: 25·7-54·6 kg/m2) completed this stratified, randomised, double-blind, placebo-controlled study (WH: n 16, age 27·4 (sd 5·0) years; CAS: n 15, age 30·3 (sd 8·1) years; PLA: n 13, age 28·5 (sd 7·2) years). The participants came to the laboratory at baseline (visit 1) and again in the morning after night-time ingestion of either protein or PLA (visit 2)...
August 14, 2014: British Journal of Nutrition
Paul J Arciero, Daniel Baur, Scott Connelly, Michael J Ormsbee
The present study examined the effects of timed ingestion of supplemental protein (20-g servings of whey protein, 3×/day), added to the habitual diet of free-living overweight/obese adults and subsequently randomized to either whey protein only (P; n = 24), whey protein and resistance exercise (P + RT; n = 27), or a whey protein and multimode exercise training program [protein and resistance exercise, intervals, stretching/yoga/Pilates, endurance exercise (PRISE); n = 28]. Total and regional body composition and visceral adipose tissue (VAT) mass (dual-energy X-ray absorptiometry), insulin sensitivity [homeostasis model assessment-estimated insulin resistance (HOMA-IR)], plasma lipids and adipokines, and feelings of hunger and satiety (visual analog scales) were measured before and after the 16-wk intervention...
July 1, 2014: Journal of Applied Physiology
Daren Heyland, John Muscedere, Paul E Wischmeyer, Deborah Cook, Gwynne Jones, Martin Albert, Gunnar Elke, Mette M Berger, Andrew G Day
BACKGROUND: Critically ill patients have considerable oxidative stress. Glutamine and antioxidant supplementation may offer therapeutic benefit, although current data are conflicting. METHODS: In this blinded 2-by-2 factorial trial, we randomly assigned 1223 critically ill adults in 40 intensive care units (ICUs) in Canada, the United States, and Europe who had multiorgan failure and were receiving mechanical ventilation to receive supplements of glutamine, antioxidants, both, or placebo...
April 18, 2013: New England Journal of Medicine
Adil E Bharucha, Spencer D Dorn, Anthony Lembo, Amanda Pressman
No abstract text is available yet for this article.
January 2013: Gastroenterology
Samara Joy Nielsen, Brian K Kit, Yutaka Aoki, Cynthia L Ogden
BACKGROUND: Seafood is part of a healthy diet, but seafood can also contain methyl mercury-a neurotoxin. OBJECTIVE: The objective was to describe seafood consumption in US adults and to explore the relation between seafood consumption and blood mercury. DESIGN: Seafood consumption, obtained from a food-frequency questionnaire, and blood mercury data were available for 10,673 adults who participated in the 2007-2010 NHANES-a cross-sectional nationally representative sample of the US population...
May 2014: American Journal of Clinical Nutrition
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