collection
https://read.qxmd.com/read/22465849/chronic-exposure-to-methylphenidate-impairs-appendicular-bone-quality-in-young-rats
#1
JOURNAL ARTICLE
David E Komatsu, Panayotis K Thanos, Michelle N Mary, Haden A Janda, Christine M John, Lisa Robison, Mala Ananth, James M Swanson, Nora D Volkow, Michael Hadjiargyrou
Methylphenidate (MP) is a psychostimulant widely prescribed to treat Attention Deficit Hyperactivity Disorder (ADHD). Although generally well tolerated, growth deficits have been reported in children and adolescents undergoing MP treatment. This study was designed to elucidate the skeletal effects of chronic MP administration in adolescent rats. Male, 4-week-old rats received one of two doses of MP (MP-Low or MP-High) delivered for 8 h a day via drinking water, or were untreated (water only). After 13 weeks, half were sacrificed (N=12/group) and the remaining rats were left to recover, untreated for 5 additional weeks...
June 2012: Bone
https://read.qxmd.com/read/20502230/psychiatric-risk-factors-in-pediatric-hand-fractures
#2
JOURNAL ARTICLE
Kagan Ozer, Syed Gillani, Allison Williams, David J Hak
BACKGROUND: Various psychopathologies are becoming more commonly recognized as a cause of violence in the pediatric population. In this study, we aimed to investigate (1) the link between the pediatric hand fractures and psychopathology and (2) the prevalence of repeated hand injuries in the same population. METHOD: We retrospectively reviewed 208 patients treated at a level 1 trauma center and recorded age, sex, past medical and psychiatric history as well as type, etiology, and treatment of hand fractures for analysis...
June 2010: Journal of Pediatric Orthopedics
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