Iain Bressendorff, Ditte Hansen, Morten Schou, Charlotte Kragelund, My Svensson, Bahram Hashemi, Tilde Kristensen, Marie Houmaa Vrist, Rikke Borg, Birgitte Tougaard, Kristine Borg, Henrik Øder Hjortkjær, Cathrine Helgestad Kristiansen, Nicholas Carlson, Mohammad Nasiri, Haseem Ashraf, Andreas Pasch, Lisbet Brandi
SIGNIFICANCE STATEMENT: Magnesium prevents vascular calcification in animals with CKD. In addition, lower serum magnesium is associated with higher risk of cardiovascular events in CKD. In a randomized, double-blinded, placebo-controlled trial, the authors investigated the effects of magnesium supplementation versus placebo on vascular calcification in patients with predialysis CKD. Despite significant increases in plasma magnesium among study participants who received magnesium compared with those who received placebo, magnesium supplementation did not slow the progression of vascular calcification in study participants...
May 1, 2023: Journal of the American Society of Nephrology: JASN