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MULTICENTER STUDY
Dana M Block-Abraham, Ozhan M Turan, Lauren E Doyle, Jerome N Kopelman, Robert O Atlas, Chuka B Jenkins, Miriam G Blitzer, Ahmet A Baschat
OBJECTIVE: The residual risk of preeclampsia in high-risk women on aspirin prophylaxis exceeds that of low-risk populations, and this study aimed to identify first-trimester maternal characteristics associated with aspirin prophylaxis failure. METHODS: This is a nested cohort study of prospectively enrolled women with verified initiation of risk-indicated aspirin prophylaxis by 16 weeks of gestation. First-trimester maternal history, demographics, anthropometry, ultrasound parameters, and serum analytes were compared between women who developed preeclampsia and those who did not...
March 2014: Obstetrics and Gynecology
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