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Stroke Medicine & Surgery Bull...
Stroke Medicine & Surgery Bulletin: Healthcare Library of Northern Ireland
• Collection of new stroke articles, prepared by Richard Fallis, Specialist Librarian for Medicine, Dentistry & Healthcare Sciences: https://libguides.qub.ac.uk/healthcarelibrary/medicinebulletins/stroke
#1
JOURNAL ARTICLE
Deborah Rose, Annie Cavalier, Wayneho Kam, Sarah Cantrell, Jay Lusk, Matthew Schrag, Shadi Yaghi, Christoph Stretz, Adam de Havenon, Ian J Saldanha, Teddy Y Wu, Anna Ranta, P Alan Barber, Elizabeth Marriott, Wayne Feng, Andrzej S Kosinski, Daniel Laskowitz, Sven Poli, Brian Mac Grory
BACKGROUND: Prior systematic reviews have compared the efficacy of intravenous tenecteplase and alteplase in acute ischemic stroke, assigning their relative complications as a secondary objective. The objective of the present study is to determine whether the risk of treatment complications differs between patients treated with either agent. METHODS: We performed a systematic review including interventional studies and prospective and retrospective, observational studies enrolling adult patients treated with intravenous tenecteplase for ischemic stroke (both comparative and noncomparative with alteplase)...
May 2023: Stroke; a Journal of Cerebral Circulation
#2
JOURNAL ARTICLE
John J McCabe, Cathal Walsh, Sarah Gorey, Katie Harris, Pablo Hervella, Ramon Iglesias-Rey, Christina Jern, Linxin Li, Nobukazu Miyamoto, Joan Montaner, Annie Pedersen, Francisco Purroy, Peter M Rothwell, Catherine Sudlow, Yuji Ueno, Mikel Vicente-Pascual, William Whiteley, Mark Woodward, Peter J Kelly
BACKGROUND: Anti-inflammatory therapies reduce recurrent vascular events in coronary disease. Existing studies have reported highly conflicting findings for the association of blood inflammatory markers with vascular recurrence after stroke leading to uncertainty about the potential of anti-inflammatory therapies after stroke and no consensus about the utility of measurement of inflammatory markers in current guidelines. METHODS: We investigated the association between hsCRP (high-sensitivity C-reactive protein), IL-6 (interluekin-6), and recurrent major adverse cardiovascular events (MACE), and stroke from individual participant data from 8420 patients with ischemic stroke/transient ischemic attack from 10 prospective studies...
May 2023: Stroke; a Journal of Cerebral Circulation
#3
JOURNAL ARTICLE
Eleonora De Matteis, Federico De Santis, Raffaele Ornello, Bruno Censori, Valentina Puglisi, Luisa Vinciguerra, Alessia Giossi, Pietro Di Viesti, Vincenzo Inchingolo, Giovanni Matteo Fratta, Marina Diomedi, Maria Rosaria Bagnato, Silvia Cenciarelli, Chiara Bedetti, Chiara Padiglioni, Tiziana Tassinari, Valentina Saia, Alessandro Russo, Marco Petruzzellis, Domenico Maria Mezzapesa, Martina Caccamo, Giuseppe Rinaldi, Alessandra Bavaro, Maurizio Paciaroni, Maria Giulia Mosconi, Matteo Foschi, Pietro Querzani, Francesco Muscia, Serena Gallo Cassarino, Paolo Candelaresi, Antonio De Mase, Maria Guarino, Letizia Maria Cupini, Enzo Sanzaro, Andrea Zini, Salvatore La Spada, Carmela Palmieri, Federica Nicoletta Sepe, Simone Beretta, Cristina Paci, Emanuele Alessandro Caggia, Maria Vittoria De Angelis, Laura Bonanni, Gino Volpi, Rossana Tassi, Francesca Pistoia, Umberto Scoditti, Agnese Tonon, Giovanna Viticchi, Giampietro Ruzza, Patrizia Nencini, Anna Cavallini, Danilo Toni, Stefano Ricci, Simona Sacco
BACKGROUND: Randomized controlled trials (RCTs) proved that short-term (21-90 days) dual antiplatelet therapy (DAPT) reduces the risk of early ischemic recurrences after a noncardioembolic minor stroke or high-risk transient ischemic attack (TIA) without substantially increasing the hemorrhagic risk. We aimed at understanding whether and how real-world use of DAPT differs from RCTs. METHODS: READAPT (Real-Life Study on Short-Term Dual Antiplatelet Treatment in Patients With Ischemic Stroke or TIA) is a prospective cohort study including >18-year-old patients treated with DAPT after a noncardioembolic minor ischemic stroke or high-risk TIA from 51 Italian centers...
May 2023: Stroke; a Journal of Cerebral Circulation
#4
JOURNAL ARTICLE
Sonia Alamowitch, Guillaume Turc, Lina Palaiodimou, Andrew Bivard, Alan Cameron, Gian Marco De Marchis, Annette Fromm, Janika Kõrv, Melinda B Roaldsen, Aristeidis H Katsanos, Georgios Tsivgoulis
Within the last year, four randomised-controlled clinical trials (RCTs) have been published comparing intravenous thrombolysis (IVT) with tenecteplase and alteplase in acute ischaemic stroke (AIS) patients with a non-inferiority design for three of them. An expedited recommendation process was initiated by the European Stroke Organisation (ESO) and conducted according to ESO standard operating procedure based on the Grading of Recommendations, Assessment, Development and Evaluations (GRADE) framework. We identified three relevant Population, Intervention, Comparator, Outcome (PICO) questions, performed systematic reviews of the literature and meta-analyses, assessed the quality of the available evidence, and wrote evidence-based recommendations...
March 2023: European Stroke Journal
#5
REVIEW
Mikel Terceño, Saima Bashir, Juan Cienfuegos, Alan Murillo, Víctor Augusto Vera-Monge, Laura Pardo, Montserrat Reina, Carme Gubern-Mérida, Dolors Puigoriol-Illamola, Laia Carballo, Anna Costa, Maria Buxó, Joaquín Serena, Yolanda Silva
PURPOSE: The optimal anesthetic approach in the endovascular treatment (EVT) of patients with posterior circulation large vessel occlusion (PC-LVO) strokes is not clear. Little data has been published and no randomized clinical trials have been conducted so far. We aimed to perform an updated meta-analysis to compare clinical and procedural outcomes between conscious sedation (CS) and general anesthesia (GA). METHODS: We reviewed the literature of the studies reporting CS and GA in patients with endovascularly-treated PC-LVO...
March 2023: European Stroke Journal
#6
JOURNAL ARTICLE
Brian Stamm, Regina Royan, Gabriela Trifan, Ronald Alvarado-Dyer, Faddi G Saleh Velez, William Taylor, Pranusha Pinna, Nicholas J Reish, Alejandro Vargas, Fernando D Goldenberg, Michael J Schneck, José Biller, Fernando Testai, Fan Z Caprio, Sherry H Chou, Philip B Gorelick, Eric M Liotta, Ayush Batra
OBJECTIVES: The COVID-19 pandemic has heightened awareness of health disparities associated with socioeconomic status (SES) across the United States. We examined whether household income is associated with functional outcomes after stroke and COVID-19. MATERIALS AND METHODS: This was a multi-institutional, retrospective cohort study of consecutively hospitalized patients with SARS-CoV-2 and radiographically confirmed stroke presenting from March through November 2020 to any of five comprehensive stroke centers in metropolitan Chicago, Illinois, USA...
February 20, 2023: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#7
JOURNAL ARTICLE
Camila Lima Gervásio Mendes, Marcela Aline Fernandes Braga, Edvânia Andrade de Moura Silva, Aline Alvim Scianni, Luci Fuscaldi Teixeira-Salmela, Kênia Kiefer Parreiras de Menezes, Iza de Faria-Fortini, Christina Danielli Coelho de Morais Faria
PURPOSE: To compare quality of life (QOL) of individuals with stroke three months after hospital discharge, using generic and specific QOL measures, before and during the COVID-19 pandemic. METHODS: Individuals, who were admitted to a public hospital, were recruited and evaluated before (G1) and during (G2) the COVID-19 pandemic. The groups were matched for age, sex, socio-economic status, and levels of stroke severity (National Institutes of Health Stroke Scale) and functional dependence (Modified Barthel Index)...
March 13, 2023: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#8
JOURNAL ARTICLE
Kirsty Ward, Andy Vail, Alan Cameron, Mira Katan, Gregory Yh Lip, Jesse Dawson, Craig J Smith, Amit K Kishore
BACKGROUND: Several molecular biomarkers are available that predict newly detected atrial fibrillation (NDAF). We aimed to identify such biomarkers that predict NDAF after an Ischaemic stroke (IS)/Transient Ischaemic Attack (TIA) and evaluate their performance. METHODS: A systematic review was undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement. Studies of patients with IS, TIA, or both, who underwent ECG monitoring for ⩾24 h, which reported molecular biomarkers and frequency of NDAF after electronic searches of multiple databases were included...
March 2023: European Stroke Journal
#9
JOURNAL ARTICLE
Yirong Chen, Lining Yang, Xiaohong Li, Lu Tang, Yan Pi, Dingqun Bai
OBJECTIVE: To evaluate the effect of non-invasive brain stimulation (NIBS) in improving limb motor dysfunction and daily living activity during at the phase of acute stroke. MATERIALS AND METHODS: Randomized controlled trials about the effect of NIBS on hemiparesis in acute stroke were retrieved from databases of China National Knowledge Infrastructure (CNKI), China Science and Technology Journal Database (VIP), Wanfang Data, CBM, PubMed, Embase, Cochrane Library, and Web of Science from inception until January 3rd 2022...
February 4, 2023: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
#10
REVIEW
Xiaoqin Wang, Yanfang Ma, Xu Hui, Meixuan Li, Jing Li, Jinhui Tian, Qi Wang, Peijing Yan, Jianfeng Li, Ping Xie, Kehu Yang, Liang Yao
BACKGROUND: Deep vein thrombosis (DVT) is a condition in which a clot forms in the deep veins, most commonly of the leg. It occurs in approximately one in 1000 people. If left untreated, the clot can travel up to the lungs and cause a potentially life-threatening pulmonary embolism (PE). Previously, a DVT was treated with the anticoagulants heparin and vitamin K antagonists. However, two forms of direct oral anticoagulants (DOACs) have been developed: oral direct thrombin inhibitors (DTIs) and oral factor Xa inhibitors, which have characteristics that may be favourable compared to conventional treatment, including oral administration, a predictable effect, lack of frequent monitoring or dose adjustment and few known drug interactions...
April 14, 2023: Cochrane Database of Systematic Reviews
#11
JOURNAL ARTICLE
Ernst Mayerhofer, Christoph Strecker, Heiko Becker, Marios K Georgakis, Md Mesbah Uddin, Michael M Hoffmann, Niroshan Nadarajah, Manja Meggendorfer, Torsten Haferlach, Jonathan Rosand, Pradeep Natarajan, Christopher D Anderson, Andreas Harloff, Gregor Hoermann
BACKGROUND: Undetermined stroke etiology hampers optimal secondary prevention in a large proportion of young patients. We explored whether genetic screening for clonal hematopoiesis of indetermined potential (CHIP), a novel risk factor for stroke, could identify patients with myeloid precursor lesions or covert myeloid neoplasm requiring specific treatment. METHODS: We performed targeted sequencing on 56 genes recurrently mutated in hematologic neoplasms in a prospective cohort of patients with acute brain ischemia between 18 and 60 years...
February 15, 2023: Stroke; a Journal of Cerebral Circulation
#12
JOURNAL ARTICLE
Liyuan Pu, Li Wang, Ruijie Zhang, Tian Zhao, Yannan Jiang, Liyuan Han
BACKGROUND: We projected global trends in ischemic stroke from 2020 to 2030 according to age, sex, and socio-demographic index (SDI) quintile. METHODS: Estimated annual percentage changes (EAPCs) were used to project trends in the incidence of deaths from and disability-adjusted life years (DALYs) due to ischemic stroke between 2020 and 2030. EAPCs were computed using generalized additive models and data from the Global Burden of Disease study during the 1990 to 2019 period...
May 2023: Stroke; a Journal of Cerebral Circulation
#13
JOURNAL ARTICLE
Georgios Tsivgoulis, Lina Palaiodimou, Sokratis Triantafyllou, Martin Köhrmann, Polychronis Dilaveris, Konstantinos Tsioufis, Gkikas Magiorkinis, Christos Krogias, Peter D Schellinger, Valeria Caso, Maurizio Paciaroni, Mukul Sharma, Robin Lemmens, David J Gladstone, Tommaso Sanna, Rolf Wachter, Gerasimos Filippatos, Aristeidis H Katsanos
INTRODUCTION: Prolonged cardiac monitoring (PCM) substantially improves the detection of subclinical atrial fibrillation (AF) among patients with history of ischemic stroke (IS), leading to prompt initiation of anticoagulants. However, whether PCM may lead to IS prevention remains equivocal. PATIENTS AND METHODS: In this systematic review and meta-analysis, randomized-controlled clinical trials (RCTs) reporting IS rates among patients with known cardiovascular risk factors, including but not limited to history of IS, who received PCM for more than 7 days versus more conservative cardiac rhythm monitoring methods were pooled...
March 2023: European Stroke Journal
1
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