collection
https://read.qxmd.com/read/24842437/acp-journal-club-review-short-and-long-courses-of-antibiotics-do-not-differ-for-mortality-in-ventilator-associated-pneumonia
#21
COMMENT
Sameer S Kadri, Naomi P O'Grady
No abstract text is available yet for this article.
May 20, 2014: Annals of Internal Medicine
https://read.qxmd.com/read/17898575/distinguishing-between-transfusion-related-acute-lung-injury-and-transfusion-associated-circulatory-overload
#22
REVIEW
Robert C Skeate, Ted Eastlund
PURPOSE OF REVIEW: The purpose of this review is to provide an overview of concepts recently presented in the literature that impact our understanding of transfusion related acute lung injury (TRALI) and transfusion associated circulatory overload (TACO), and how to distinguish between the two disorders. RECENT FINDINGS: An exceptionally clear review article by Brux and Sachs clarified the two-hit model of TRALI pathogenesis. The TRALI definition developed at the 2004 consensus conference helped demonstrate that TRALI is likely underreported...
November 2007: Current Opinion in Hematology
https://read.qxmd.com/read/23984731/severe-sepsis-and-septic-shock
#23
REVIEW
Derek C Angus, Tom van der Poll
New England Journal of Medicine, Volume 369, Issue 9, Page 840-851, August 2013.
August 29, 2013: New England Journal of Medicine
https://read.qxmd.com/read/24652410/ventilator-associated-pneumonia-during-weaning-from-mechanical-ventilation-role-of-fluid-management
#24
RANDOMIZED CONTROLLED TRIAL
Armand Mekontso Dessap, Sandrine Katsahian, Ferran Roche-Campo, Hugo Varet, Achille Kouatchet, Vinko Tomicic, Gaetan Beduneau, Romain Sonneville, Samir Jaber, Michael Darmon, Diego Castanares-Zapatero, Laurent Brochard, Christian Brun-Buisson
BACKGROUND: Pulmonary edema may alter alveolar bacterial clearance and infectivity. Manipulation of fluid balance aimed at reducing fluid overload may, therefore, influence ventilator-associated pneumonia (VAP) occurrence in intubated patients. The objective of the present study was to assess the impact of a depletive fluid-management strategy on ventilator-associated complication (VAC) and VAP occurrence during weaning from mechanical ventilation. METHODS: We used data from the B-type Natriuretic Peptide for the Fluid Management of Weaning (BMW) randomized controlled trial performed in nine ICUs across Europe and America...
July 2014: Chest
https://read.qxmd.com/read/24635772/albumin-replacement-in-patients-with-severe-sepsis-or-septic-shock
#25
RANDOMIZED CONTROLLED TRIAL
Pietro Caironi, Gianni Tognoni, Serge Masson, Roberto Fumagalli, Antonio Pesenti, Marilena Romero, Caterina Fanizza, Luisa Caspani, Stefano Faenza, Giacomo Grasselli, Gaetano Iapichino, Massimo Antonelli, Vieri Parrini, Gilberto Fiore, Roberto Latini, Luciano Gattinoni
BACKGROUND: Although previous studies have suggested the potential advantages of albumin administration in patients with severe sepsis, its efficacy has not been fully established. METHODS: In this multicenter, open-label trial, we randomly assigned 1818 patients with severe sepsis, in 100 intensive care units (ICUs), to receive either 20% albumin and crystalloid solution or crystalloid solution alone. In the albumin group, the target serum albumin concentration was 30 g per liter or more until discharge from the ICU or 28 days after randomization...
April 10, 2014: New England Journal of Medicine
https://read.qxmd.com/read/24635771/is-there-a-good-map-for-septic-shock
#26
EDITORIAL
James A Russell
New England Journal of Medicine, Volume 0, Issue 0, Ahead of Print.
April 24, 2014: New England Journal of Medicine
https://read.qxmd.com/read/24635770/high-versus-low-blood-pressure-target-in-patients-with-septic-shock
#27
RANDOMIZED CONTROLLED TRIAL
Pierre Asfar, Ferhat Meziani, Jean-François Hamel, Fabien Grelon, Bruno Megarbane, Nadia Anguel, Jean-Paul Mira, Pierre-François Dequin, Soizic Gergaud, Nicolas Weiss, François Legay, Yves Le Tulzo, Marie Conrad, René Robert, Frédéric Gonzalez, Christophe Guitton, Fabienne Tamion, Jean-Marie Tonnelier, Pierre Guezennec, Thierry Van Der Linden, Antoine Vieillard-Baron, Eric Mariotte, Gaël Pradel, Olivier Lesieur, Jean-Damien Ricard, Fabien Hervé, Damien du Cheyron, Claude Guerin, Alain Mercat, Jean-Louis Teboul, Peter Radermacher
BACKGROUND: The Surviving Sepsis Campaign recommends targeting a mean arterial pressure of at least 65 mm Hg during initial resuscitation of patients with septic shock. However, whether this blood-pressure target is more or less effective than a higher target is unknown. METHODS: In a multicenter, open-label trial, we randomly assigned 776 patients with septic shock to undergo resuscitation with a mean arterial pressure target of either 80 to 85 mm Hg (high-target group) or 65 to 70 mm Hg (low-target group)...
April 24, 2014: New England Journal of Medicine
https://read.qxmd.com/read/24108515/effects-of-fluid-resuscitation-with-colloids-vs-crystalloids-on-mortality-in-critically-ill-patients-presenting-with-hypovolemic-shock-the-cristal-randomized-trial
#28
RANDOMIZED CONTROLLED TRIAL
Djillali Annane, Shidasp Siami, Samir Jaber, Claude Martin, Souheil Elatrous, Adrien Descorps Declère, Jean Charles Preiser, Hervé Outin, Gilles Troché, Claire Charpentier, Jean Louis Trouillet, Antoine Kimmoun, Xavier Forceville, Michael Darmon, Olivier Lesur, Jean Reignier, Jean Régnier, Fékri Abroug, Philippe Berger, Christophe Clec'h, Christophe Cle'h, Joël Cousson, Laure Thibault, Sylvie Chevret
IMPORTANCE: Evidence supporting the choice of intravenous colloid vs crystalloid solutions for management of hypovolemic shock remains unclear. OBJECTIVE: To test whether use of colloids compared with crystalloids for fluid resuscitation alters mortality in patients admitted to the intensive care unit (ICU) with hypovolemic shock. DESIGN, SETTING, AND PARTICIPANTS: A multicenter, randomized clinical trial stratified by case mix (sepsis, trauma, or hypovolemic shock without sepsis or trauma)...
November 6, 2013: JAMA
https://read.qxmd.com/read/10824078/hyponatremia
#29
REVIEW
H J Adrogué, N E Madias
No abstract text is available yet for this article.
May 25, 2000: New England Journal of Medicine
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