Kian Fan Chung, Sally E Wenzel, Jan L Brozek, Andrew Bush, Mario Castro, Peter J Sterk, Ian M Adcock, Eric D Bateman, Elisabeth H Bel, Eugene R Bleecker, Louis-Philippe Boulet, Christopher Brightling, Pascal Chanez, Sven-Erik Dahlen, Ratko Djukanovic, Urs Frey, Mina Gaga, Peter Gibson, Qutayba Hamid, Nizar N Jajour, Thais Mauad, Ronald L Sorkness, W Gerald Teague
Severe or therapy-resistant asthma is increasingly recognised as a major unmet need. A Task Force, supported by the European Respiratory Society and American Thoracic Society, reviewed the definition and provided recommendations and guidelines on the evaluation and treatment of severe asthma in children and adults. A literature review was performed, followed by discussion by an expert committee according to the GRADE (Grading of Recommendations, Assessment, Development and Evaluation) approach for development of specific clinical recommendations...
February 2014: European Respiratory Journal