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Ostheimer Lecture 2020

The Gerald W. Ostheimer lecture is given each year at the Society of Obstetric Anesthesia & Perinatology Annual Meeting. It is intended to summarize the years most relevant scientific literature in #OBAnes

https://read.qxmd.com/read/30738027/preeclampsia-the-role-of-persistent-endothelial-cells-in-uteroplacental-arteries
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JOURNAL ARTICLE
Ivo Brosens, Jan J Brosens, Joanne Muter, Patrick Puttemans, Giuseppe Benagiano
We explore the potential role of the endothelial lining of uteroplacental arteries in the pathogenesis of preeclampsia, a severe pregnancy disorder characterized by incomplete invasion of the uterine vasculature by extravillous trophoblast and angiogenic imbalance. In normal pregnancy, the endothelium disappears progressively from the uteroplacental arteries and is replaced by trophoblast and deposition of fibrofibrinoid structure, underpinning the so-called physiological transformation of uterine spiral arteries...
September 2019: American Journal of Obstetrics and Gynecology
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