collection
https://read.qxmd.com/read/31236286/glycopyrrolate-in-comparison-to-hyoscine-hydrobromide-and-placebo-in-the-treatment-of-hypersalivation-induced-by-clozapine-gothic1-a-feasibility-study
#21
JOURNAL ARTICLE
Inti Qurashi, Simon Chu, Richard Drake, Victoria Hartley, Imran Chaudhry, J F W Deakin, Nusrat Husain
Background: Clozapine-induced hypersalivation (CIH) is a common side effect of clozapine treatment and is disliked by clozapine patients, potentially threatening adherence to clozapine treatment. We proposed a trial of alternative medications, hyoscine and glycopyrrolate, for the treatment of CIH and the primary objective of the feasibility study was to assess the recruitment and retention of community clozapine patients as well as assess the metrics of the primary hypersalivation measure...
2019: Pilot and Feasibility Studies
https://read.qxmd.com/read/27871302/glycopyrrolate-in-comparison-to-hyoscine-hydrobromide-and-placebo-in-the-treatment-of-hypersalivation-induced-by-clozapine-gothic1-study-protocol-for-a-randomised-controlled-feasibility-study
#22
RANDOMIZED CONTROLLED TRIAL
Inti Qurashi, Simon Chu, Nusrat Husain, Richard J Drake, Imran Chaudhry, J F W Deakin
BACKGROUND: Clozapine is the only medication licensed for the treatment of resistant schizophrenia in the UK. Although efficacious, a common and unpopular side effect of clozapine treatment is clozapine-induced hypersalivation (CIH), which can contribute to non-adherence. The standard treatment for CIH in the UK is hyoscine hydrobromide but this may aggravate cognitive deficits in patients with schizophrenia while glycopyrrolate may be an effective alternative with a more tolerable side effect profile...
November 21, 2016: Trials
https://read.qxmd.com/read/31292014/heated-humidified-high-flow-nasal-cannula-for-preterm-infants-an-updated-systematic-review-and-meta-analysis
#23
JOURNAL ARTICLE
Nigel Fleeman, Yenal Dundar, Prakesh S Shah, Ben Nj Shaw
BACKGROUND: Heated humidified high-flow nasal cannula (HHHFNC) is gaining popularity as a mode of respiratory support. We updated a systematic review and meta-analyses examining the efficacy and safety of HHHFNC compared with standard treatments for preterm infants. The primary outcome was the need for reintubation for preterm infants following mechanical ventilation (post-extubation analysis) or need for intubation for preterm infants not previously intubated (analysis of primary respiratory support)...
2019: International Journal of Technology Assessment in Health Care
https://read.qxmd.com/read/31381244/what-to-look-for-during-constant-observations-expert-consensus-and-a-tool-for-observations-recording
#24
JOURNAL ARTICLE
Simon Chu, Katie Lambert, Alison Baker
WHAT IS KNOWN ON THE SUBJECT?: Supportive observations is the practice of closely monitoring patients who are acutely unwell in order to keep them safe. There are no formal guidelines for nursing staff on what to observe during observations. WHAT THIS PAPER ADDS TO EXISTING KNOWLEDGE?: A consensus of expert opinion suggests that the clinically meaningful behaviours in supportive observations focus on six factors: agitation, self-harm and suicide, violence, negative influence, disengagement and positive behaviour...
February 2020: Journal of Psychiatric and Mental Health Nursing
https://read.qxmd.com/read/30806042/a-preliminary-service-evaluation-of-a-personality-disorder-case-management-service
#25
JOURNAL ARTICLE
Simon Graham, Kathia Sullivan, Laura Briggs, Mark Goodall, Rosella Iraci Capucinello
AIMS: The aim of this study is to assess the impact of establishing a specialized community personality disorder team on out of area placements, local hospital admissions and out of hours crisis contacts for service users with borderline personality disorder. METHOD: This is a before-after interim evaluation of a new service. We tested, through a paired t-test, whether the intervention generated statistically significant differences over a range of measures of service usage, including out of area placements, local hospital admissions and out of hours crisis contacts...
May 2019: Personality and Mental Health
https://read.qxmd.com/read/29455177/nmdar-n-methyl-d-aspartate-receptor-encephalitis-in-a-patient-with-ms-multiple-sclerosis-a-rare-and-challenging-case
#26
JOURNAL ARTICLE
Sadia Suleman, Qaiser Javed
We present a rare case of N-methyl-D-aspartate receptor (NMDAR) encephalitis in a 41-year-old Caucasian woman, who initially presented with prominent neuropsychiatric symptoms on the background of pre-existing multiple sclerosis. Here, the authors navigate the muddy water between neurology and psychiatry, describing the caveats of antibody testing with a misdiagnosed case of acute and transient psychotic episode. NMDAR encephalitis in MS is a rare condition, which can be easily confused with a new onset psychotic episode...
February 17, 2018: BMJ Case Reports
https://read.qxmd.com/read/29624781/predictive-analytics-in-secure-settings
#27
JOURNAL ARTICLE
Fearnley David, Welle Dana
No abstract text is available yet for this article.
April 2018: Criminal Behaviour and Mental Health: CBMH
https://read.qxmd.com/read/29683240/editorial-for-special-issue-on-sexuality
#28
JOURNAL ARTICLE
Glynis Murphy, Paul Withers
No abstract text is available yet for this article.
April 23, 2018: Journal of Applied Research in Intellectual Disabilities: JARID
https://read.qxmd.com/read/29567558/peer-support-systems-and-professional-identity-of-student-nurses-undertaking-a-uk-learning-disability-nursing-programme
#29
JOURNAL ARTICLE
Joanne L Green
This practitioner based action research examines the implementation of the peer assisted study scheme (PASS) and individual peer mentoring in a cohort of first year undergraduate nursing students. It arose out of the desire of a small number of students in one UK university to transfer from the learning (intellectual) disabilities nursing field to other fields. The number of learning disabilities nurses is falling in England, and nursing shortages and student nurse retention generally is an international concern...
May 2018: Nurse Education in Practice
https://read.qxmd.com/read/29894243/transformational-leadership-is-this-still-relevant-to-clinical-leaders
#30
JOURNAL ARTICLE
David Lo, Judy McKimm, Alex Till
Transformational leadership theory has been at the centre of health-care leadership research for the past three decades, has had a tangible influence on the evolution of NHS leadership development strategies, and is still evident in current frameworks. This article provides an overview of the key concepts and weaknesses of transformational leadership theory and discusses its relevance within the context of the NHS working environment.
June 2, 2018: British Journal of Hospital Medicine
https://read.qxmd.com/read/29284378/assessing-protective-factors-for-violence-risk-in-u-k-general-mental-health-services-using-the-structured-assessment-of-protective-factors
#31
JOURNAL ARTICLE
Alina Haines, Andrew Brown, Syed Fahad Javaid, Fayyaz Khan, Steve Noblett, Oladipupo Omodunbi, Khurram Sadiq, Wahid Zaman, Richard Whittington
Violence risk assessment and management are key tasks in mental health services and should be guided by validated instruments covering both risk and protective factors. This article is part of an international effort to validate the Structured Assessment of Protective Factors (SAPROF) for violence. The SAPROF, Historical, Clinical, Risk Management-20 (HCR-20) and the Psychopathy Checklist-Screening Version (PCL-SV) were administered in a sample of 261 patients in U.K. forensic, general inpatient, and community mental health settings...
September 2018: International Journal of Offender Therapy and Comparative Criminology
https://read.qxmd.com/read/30621809/tick-tock-lock-night-time-confinement-in-high-security-history-practice-ethics-and-practicalities
#32
JOURNAL ARTICLE
Ed Silva, Andrew Shepherd
SummaryNight-time confinement, locking patients in their bedrooms overnight, is practiced within high-secure hospitals in the UK. This article provides context, sets out the history and reviews the ethical and pragmatic issues at stake. Thought is given to the future, where we appear to be moving toward a different approach.Declaration of interestE.S. is a consultant forensic psychiatrist at Ashworth Hospital. All his patients are confined at night. He represents the Royal College of Psychiatrists Forensic Faculty at the National Oversight Group, which is the strategic advisory body providing assurance to NHS England regarding the commissioning and provision of high-secure services...
February 2019: BJPsych Bulletin
https://read.qxmd.com/read/30223913/the-assertive-approach-to-clozapine-nasogastric-administration
#33
JOURNAL ARTICLE
Alex Till, James Selwood, Edward Silva
Aims and methodAn 'assertive approach' to clozapine, where nasogastric administration is approved, is assessed through a case-load analysis to provide the first systematic description of its use and outcomes worldwide. RESULTS: Five of the most extremely ill patients with treatment-resistant schizophrenia were established and/or maintained on clozapine, resulting in improvements to their mental state; incidents were reduced, segregation was terminated and progression to less restrictive environments was achieved...
February 2019: BJPsych Bulletin
https://read.qxmd.com/read/30206951/nonmedical-prescriber-experiences-of-training-and-competence-to-report-adverse-drug-reactions-in-the-uk
#34
JOURNAL ARTICLE
Andrew Thompson, Christine Randall, Justine Howard, Catrin Barker, Debbie Bowden, Paul Mooney, Agatha Munyika, Susan Smith, Munir Pirmohamed
WHAT IS KNOWN AND OBJECTIVE: Adverse drug reaction reporting in the UK is lower than expected based on epidemiological data. This study aims to explore (a) nonmedical prescribers' (NMP) confidence in identifying and reporting ADRs, (b) NMP prescribing habits and engagement with the Yellow Card Scheme (YCS) and (c) NMP desire for future training in the identification and reporting of ADRs. METHODS: A survey was distributed across NMP networks in the north-west of England using Survey Monkey...
February 2019: Journal of Clinical Pharmacy and Therapeutics
https://read.qxmd.com/read/27891723/the-structured-assessment-of-violence-risk-in-adults-with-intellectual-disability-a-systematic-review
#35
REVIEW
J Hounsome, R Whittington, A Brown, B Greenhill, J McGuire
BACKGROUND: While structured professional judgement approaches to assessing and managing the risk of violence have been extensively examined in mental health/forensic settings, the application of the findings to people with an intellectual disability is less extensively researched and reviewed. This review aimed to assess whether risk assessment tools have adequate predictive validity for violence in adults with an intellectual disability. METHODS: Standard systematic review methodology was used to identify and synthesize appropriate studies...
January 2018: Journal of Applied Research in Intellectual Disabilities: JARID
https://read.qxmd.com/read/29356098/a-systematic-review-of-the-diagnostic-accuracy-of-automated-tests-for-cognitive-impairment
#36
JOURNAL ARTICLE
Rabeea'h W Aslam, Vickie Bates, Yenal Dundar, Juliet Hounsome, Marty Richardson, Ashma Krishan, Rumona Dickson, Angela Boland, Joanne Fisher, Louise Robinson, Sudip Sikdar
OBJECTIVE: The aim of this review is to determine whether automated computerised tests accurately identify patients with progressive cognitive impairment and, if so, to investigate their role in monitoring disease progression and/or response to treatment. METHODS: Six electronic databases (Medline, Embase, Cochrane, Institute for Scientific Information, PsycINFO, and ProQuest) were searched from January 2005 to August 2015 to identify papers for inclusion. Studies assessing the diagnostic accuracy of automated computerised tests for mild cognitive impairment (MCI) and early dementia against a reference standard were included...
April 2018: International Journal of Geriatric Psychiatry
https://read.qxmd.com/read/28801978/mindfulness-of-voices-self-compassion-and-secure-attachment-in-relation-to-the-experience-of-hearing-voices
#37
JOURNAL ARTICLE
James Dudley, Catrin Eames, John Mulligan, Naomi Fisher
OBJECTIVES: Developing compassion towards oneself has been linked to improvement in many areas of psychological well-being, including psychosis. Furthermore, developing a non-judgemental, accepting way of relating to voices is associated with lower levels of distress for people who hear voices. These factors have also been associated with secure attachment. This study explores associations between the constructs of mindfulness of voices, self-compassion, and distress from hearing voices and how secure attachment style related to each of these variables...
March 2018: British Journal of Clinical Psychology
https://read.qxmd.com/read/29536582/attenuated-behaviour-in-cornelia-de-lange-and-fragile-x-syndromes
#38
JOURNAL ARTICLE
L Bell, C Oliver, A Wittkowski, J Moss, D Hare
BACKGROUND: Catatonia-like presentations in people with autism have been increasingly recognised within research and diagnostic guidelines. The recently developed Attenuated Behaviour Questionnaire has identified that attenuated behaviour [autistic catatonia] is very prevalent in people with autism spectrum disorders (ASDs) and associated with repetitive behaviour. In the current study, we investigated attenuated behaviour within two genetic syndromes associated with ASD and examined ASD and repetitive behaviour as longitudinal predictors of attenuated behaviour...
June 2018: Journal of Intellectual Disability Research: JIDR
https://read.qxmd.com/read/29405902/the-prevalence-of-constant-supportive-observations-in-high-medium-and-low-secure-services
#39
JOURNAL ARTICLE
Katie Lambert, Simon Chu, Chris Duffy, Victoria Hartley, Alison Baker, Jane L Ireland
Aims and method We explored the prevalence and use of constant supportive observations (CSO) in high, medium and low secure in-patient services in a single National Health Service (NHS) mental health trust. From clinical records, we extracted data on the length of time of CSO, the reason for the initiation of CSO and associated adverse incidents for all individuals who were placed on CSO between July 2013 and June 2014. RESULTS: A small number of individuals accounted for a disproportionately large proportion of CSO hours in each setting...
April 2018: BJPsych Bulletin
https://read.qxmd.com/read/29719118/cognitive-analytic-therapy-for-psychosis-a-case-series
#40
JOURNAL ARTICLE
Peter J Taylor, Alex Perry, Paul Hutton, Ranil Tan, Naomi Fisher, Chiara Focone, Diane Griffiths, Claire Seddon
OBJECTIVES: Cognitive Analytic Therapy (CAT) is an effective psychological intervention for several different mental health conditions. However, whether it is acceptable, safe, and beneficial for people with psychosis remains unclear, as is the feasibility of providing and evaluating it within a research context. The aim of this study was to begin to address these questions and to obtain for the first time a rich and detailed understanding of the experience of receiving CAT for psychosis...
May 2, 2018: Psychology and Psychotherapy
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