Nassim Kamar, Jacques Izopet, Simona Tripon, Michael Bismuth, Sophie Hillaire, Jérôme Dumortier, Sylvie Radenne, Audrey Coilly, Valérie Garrigue, Louis D'Alteroche, Matthias Buchler, Lionel Couzi, Pascal Lebray, Sebastien Dharancy, Anne Minello, Maryvonne Hourmant, Anne-Marie Roque-Afonso, Florence Abravanel, Stanislas Pol, Lionel Rostaing, Vincent Mallet
BACKGROUND: There is no established therapy for hepatitis E virus (HEV) infection. The aim of this retrospective, multicenter case series was to assess the effects of ribavirin as monotherapy for solid-organ transplant recipients with prolonged HEV viremia. METHODS: We examined the records of 59 patients who had received a solid-organ transplant (37 kidney-transplant recipients, 10 liver-transplant recipients, 5 heart-transplant recipients, 5 kidney and pancreas-transplant recipients, and 2 lung-transplant recipients)...
March 20, 2014: New England Journal of Medicine