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COMPARATIVE STUDY
Timo F W Soeterik, Harm H E van Melick, Lea M Dijksman, Douwe H Biesma, J Alfred Witjes, Jean-Paul A van Basten
OBJECTIVE: To assess the impact of multiparametric magnetic resonance imaging (mp-MRI) local tumor staging on prostate cancer risk stratification and choice of treatment. MATERIALS AND METHODS: Prostate cancer patients, newly diagnosed from 2017 to 2018 at 7 Dutch teaching hospitals were included. Risk group classification was done twice, using either digital rectal examination (DRE) or mp-MRI information. Risk group migration and rates of treatment intensification associated with mp-MRI upstaging were established...
January 2021: Urology
#22
REVIEW
Jeffrey P Weiss, Karel Everaert
Nocturnal polyuria (NP), characterized by overproduction of urine at night (greater than 20%-33% of total 24-hour urine volume depending on age), is a major contributing factor in most nocturia cases. Nocturia can be caused by intake, urological, nephrological, hormonal, sleep, and cardiovascular factors. It is therefore important to accurately diagnose both the type of nocturia and the potentially associated medical conditions to determine appropriate treatment. Diagnostic tools, in addition to a thorough history and physical examination, include voiding/bladder diary analyses and questionnaires to diagnose nocturia type (NP, diminished nocturnal/global bladder capacity, global polyuria) and causative factors...
November 2019: Urology
#23
JOURNAL ARTICLE
Douglas K Owens, Karina W Davidson, Alex H Krist, Michael J Barry, Michael Cabana, Aaron B Caughey, Chyke A Doubeni, John W Epling, Martha Kubik, C Seth Landefeld, Carol M Mangione, Lori Pbert, Michael Silverstein, Melissa A Simon, Chien-Wen Tseng, John B Wong
IMPORTANCE: Among the general adult population, women (across all ages) have the highest prevalence of asymptomatic bacteriuria, although rates increase with age among both men and women. Asymptomatic bacteriuria is present in an estimated 1% to 6% of premenopausal women and an estimated 2% to 10% of pregnant women and is associated with pyelonephritis, one of the most common nonobstetric reasons for hospitalization in pregnant women. Among pregnant persons, pyelonephritis is associated with perinatal complications including septicemia, respiratory distress, low birth weight, and spontaneous preterm birth...
September 24, 2019: JAMA
#24
JOURNAL ARTICLE
Carolyn J Crandall
No abstract text is available yet for this article.
September 26, 2019: JAMA
#25
JOURNAL ARTICLE
Rianne R M Engels, Bas Israël, Anwar R Padhani, Jelle O Barentsz
BACKGROUND: Acquiring multiparametric magnetic resonance images of the prostate is not a simple "push-button" approach. OBJECTIVE: To show how image acquisition of prostate multiparametric Magnetic Resonance Imaging (mpMRI) can be optimized. DESIGN, SETTING, AND PARTICIPANTS: Image protocols, magnetic field strength choice, and the use of receiver coils are discussed. In addition, patient preparation and the recognition, prevention, and mitigation of artifacts are evaluated...
April 2020: European Urology
#26
REVIEW
Thomas B L Lam, Steven MacLennan, Peter-Paul M Willemse, Malcolm D Mason, Karin Plass, Robert Shepherd, Ruud Baanders, Chris H Bangma, Anders Bjartell, Alberto Bossi, Erik Briers, Alberto Briganti, Karel T Buddingh, James W F Catto, Maurizio Colecchia, Brett W Cox, Marcus G Cumberbatch, Jeff Davies, Niall F Davis, Maria De Santis, Paolo Dell'Oglio, André Deschamps, James F Donaldson, Shin Egawa, Christian D Fankhauser, Stefano Fanti, Nicola Fossati, Giorgio Gandaglia, Silke Gillessen, Nikolaos Grivas, Tobias Gross, Jeremy P Grummet, Ann M Henry, Alexandre Ingels, Jacques Irani, Michael Lardas, Matthew Liew, Daniel W Lin, Lisa Moris, Muhammad Imran Omar, Karl H Pang, Catherine C Paterson, Raphaële Renard-Penna, Maria J Ribal, Monique J Roobol, Morgan Rouprêt, Olivier Rouvière, Gemma Sancho Pardo, Jonathan Richenberg, Ivo G Schoots, J P Michiel Sedelaar, Phillip Stricker, Derya Tilki, Susanne Vahr Lauridsen, Roderick C N van den Bergh, Thomas Van den Broeck, Theodorus H van der Kwast, Henk G van der Poel, Geert J L H van Leenders, Murali Varma, Philippe D Violette, Christopher J D Wallis, Thomas Wiegel, Karen Wilkinson, Fabio Zattoni, James M O N'Dow, Hendrik Van Poppel, Philip Cornford, Nicolas Mottet
BACKGROUND: There is uncertainty in deferred active treatment (DAT) programmes, regarding patient selection, follow-up and monitoring, reclassification, and which outcome measures should be prioritised. OBJECTIVE: To develop consensus statements for all domains of DAT. DESIGN, SETTING, AND PARTICIPANTS: A protocol-driven, three phase study was undertaken by the European Association of Urology (EAU)-European Association of Nuclear Medicine (EANM)-European Society for Radiotherapy and Oncology (ESTRO)-European Association of Urology Section of Urological Research (ESUR)-International Society of Geriatric Oncology (SIOG) Prostate Cancer Guideline Panel in conjunction with partner organisations, including the following: (1) a systematic review to describe heterogeneity across all domains; (2) a two-round Delphi survey involving a large, international panel of stakeholders, including healthcare practitioners (HCPs) and patients; and (3) a consensus group meeting attended by stakeholder group representatives...
December 2019: European Urology
#27
REVIEW
Robert Craig Sineath, Akanksha Mehta
The presence of cancer in the testis, as well as the therapies used to treat testis cancer, can impair fertility potential for affected men. Fertility preservation is an important aspect of survivorship care and should be offered to all patients before initiating treatment. The only established means of fertility preservation in men is cryopreservation of sperm. Methods for fertility preservation in prepubertal boys are still experimental. Physicians treating men with testicular cancer should be familiar with the available options...
August 2019: Urologic Clinics of North America
#28
REVIEW
Armando Stabile, Francesco Giganti, Andrew B Rosenkrantz, Samir S Taneja, Geert Villeirs, Inderbir S Gill, Clare Allen, Mark Emberton, Caroline M Moore, Veeru Kasivisvanathan
The current diagnostic pathway for prostate cancer has resulted in overdiagnosis and consequent overtreatment as well as underdiagnosis and missed diagnoses in many men. Multiparametric MRI (mpMRI) of the prostate has been identified as a test that could mitigate these diagnostic errors. The performance of mpMRI can vary depending on the population being studied, the execution of the MRI itself, the experience of the radiologist, whether additional biomarkers are considered and whether mpMRI-targeted biopsy is carried out alone or in addition to systematic biopsy...
January 2020: Nature Reviews. Urology
#29
RANDOMIZED CONTROLLED TRIAL
Vivian W Sung, Diane Borello-France, Diane K Newman, Holly E Richter, Emily S Lukacz, Pamela Moalli, Alison C Weidner, Ariana L Smith, Gena Dunivan, Beri Ridgeway, John N Nguyen, Donna Mazloomdoost, Benjamin Carper, Marie G Gantz
IMPORTANCE: Mixed urinary incontinence, including both stress and urgency incontinence, has adverse effects on a woman's quality of life. Studies evaluating treatments to simultaneously improve both components are lacking. OBJECTIVE: To determine whether combining behavioral and pelvic floor muscle therapy with midurethral sling is more effective than sling alone for improving mixed urinary incontinence symptoms. DESIGN, SETTING, AND PARTICIPANTS: Randomized clinical trial involving women 21 years or older with moderate or severe stress and urgency urinary incontinence symptoms for at least 3 months, and at least 1 stress and 1 urgency incontinence episode on a 3-day bladder diary...
September 17, 2019: JAMA
#30
REVIEW
Carolyn A Salter, John P Mulhall
We analysed the guidelines for testosterone therapy (TTh) produced by major international medical societies including: the American Urological Association, European Association of Urology, American Association of Clinical Endocrinologists, British Society for Sexual Medicine, Endocrine Society, International Society for Sexual Medicine, and the International Society for the Study of the Aging Male, and compared their recommendations. All the organisations were in general agreement concerning the following key points: Only men meeting the criteria for testosterone deficiency (TD) should be treated...
November 2019: BJU International
#31
REVIEW
Jeffrey J Leow, Jens Bedke, Karim Chamie, Justin W Collins, Siamak Daneshmand, Petros Grivas, Axel Heidenreich, Edward M Messing, Trevor J Royce, Alexander I Sankin, Mark P Schoenberg, William U Shipley, Arnauld Villers, Jason A Efstathiou, Joaquim Bellmunt, Arnulf Stenzl
PURPOSE: To provide a comprehensive overview and update of the Joint Société Internationale d'Urologie-International Consultation on Urological Diseases (SIU-ICUD) Consultation on Bladder Cancer for muscle-invasive presumably node-negative bladder cancer (MIBC). METHODS: Contemporary literature was analyzed for the latest evidence in treatment options, outcomes, including radical surgery, neoadjuvant and adjuvant treatment modalities, and bladder-sparing approaches...
January 2019: World Journal of Urology
#32
REVIEW
Thulium fiber laser: the new player for kidney stone treatment? A comparison with Holmium:YAG laser.
Olivier Traxer, Etienne Xavier Keller
PURPOSE: To compare the operating modes of the Holmium:YAG laser and Thulium fiber laser. Additionally, currently available literature on Thulium fiber laser lithotripsy is reviewed. MATERIALS AND METHODS: Medline, Scopus, Embase, and Web of Science databases were searched for articles relating to the operating modes of Holmium:YAG and Thulium fiber lasers, including systematic review of articles on Thulium fiber laser lithotripsy. RESULTS: The laser beam emerging from the Holmium:YAG laser involves fundamental architectural design constraints compared to the Thulium fiber laser...
August 2020: World Journal of Urology
#33
JOURNAL ARTICLE
Osamah Al-Bayati, Aws Hasan, Deepak Pruthi, Dharam Kaushik, Michael A Liss
To perform a systematic review of modifiable risk factors associated with the incidence of renal cell cancer (RCC). A systematic search of the literature was conducted using PubMed, Cochrane, and Web of Science databases from January 1996 until August 2017. We also extracted articles from the reference lists of identified studies and reviews. We targeted modifiable risk factors for RCC to include exercise, smoking, alcohol, diet, obesity, hypertension, and diabetes. We utilized predefined inclusion criteria and the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement...
June 2019: Urologic Oncology
#34
JOURNAL ARTICLE
Takehiro Iwata, Shoji Kimura, Beat Foerster, Mohammad Abufaraj, Pierre I Karakiewicz, Felix Preisser, Yasutomo Nasu, Shahrokh F Shariat
AIM: To investigate the association of perioperative blood transfusion (PBT) with oncologic outcomes in patients with renal cell carcinoma (RCC), we conducted a systematic review and meta-analysis of the literature to clarify the long-term oncologic effect of PBT in patients undergoing nephrectomy for RCC. MATERIALS AND METHODS: We searched the MEDLINE, Web of Science, Cochrane Library and Scopus on 15th April 2018 to identify studies that compared patients who received PBT undergoing radical or partial nephrectomy for RCC to patients who did not with the aim of evaluating its impact on overall mortality (OM), cancer-specific mortality (CSM) and disease recurrence using multivariable cox regression analysis...
April 2019: Urologic Oncology
#35
JOURNAL ARTICLE
Luiz S Guedes-Barbosa
A 31-year-old man presented to an outpatient clinic with a 5-day history of oral and genital ulcers. He had a 2-year history of recurrent oral and genital lesions, and 6 months before presentation, erythema nodosum had developed on his legs. Tests for herpes simplex virus and syphilis were..
February 7, 2019: New England Journal of Medicine
#36
JOURNAL ARTICLE
Tomohiro Matsuo, Yasuyoshi Miyata, Hideki Sakai
AIMS: To assess the efficacy of salt reduction for improving nocturia in patients with high salt intake. METHODS: Changes in lower urinary symptoms and frequency volume chart by salt intake (men: 8 g/day; women: ≥7 g/day) were analyzed in this prospective study. Patients were instructed to use a brochure for salt intake restriction via interview once every four weeks. The daily salt intake was estimated by using spot urine samples. RESULTS: Two-hundred twenty-three (69...
March 2019: Neurourology and Urodynamics
#37
REVIEW
Mario Preti, Pedro Vieira-Baptista, Giuseppe Alessandro Digesu, Carol Emi Bretschneider, Margot Damaser, Oktay Demirkesen, Debra S Heller, Naside Mangir, Claudia Marchitelli, Sherif Mourad, Micheline Moyal-Barracco, Sol Peremateu, Visha Tailor, Tufan Tarcan, Elise J B De, Colleen K Stockdale
BACKGROUND: The clinical role of LASER for vulvar and vaginal treatments in gynecology and female urology is controversial. AIMS: In this best practice document, we propose recommendations for the use of LASER for gynecologic and urologic conditions such as vulvovaginal atrophy, urinary incontinence, vulvodynia, and lichen sclerosus based on a thorough literature review. MATERIALS & METHODS: This project was developed between January and September 2018...
March 2019: Neurourology and Urodynamics
#38
RANDOMIZED CONTROLLED TRIAL
Bertrand Tombal, Fred Saad, David Penson, Maha Hussain, Cora N Sternberg, Robert Morlock, Krishnan Ramaswamy, Cristina Ivanescu, Gerhardt Attard
BACKGROUND: In the PROSPER trial, enzalutamide significantly improved metastasis-free survival in patients with non-metastatic, castration-resistant prostate cancer. Here, we report the results of patient-reported outcomes of this study. METHODS: In the randomised, double-blind, placebo-controlled, phase 3 PROSPER trial, done at 254 study sites worldwide, patients aged 18 years or older with non-metastatic, castration-resistant prostate cancer and a prostate-specific antigen doubling time of up to 10 months were randomly assigned (2:1) via an interactive voice web recognition system to receive oral enzalutamide (160 mg per day) or placebo...
April 2019: Lancet Oncology
#39
JOURNAL ARTICLE
Ioannis Sokolakis, Fotios Dimitriadis, Pearline Teo, Georgios Hatzichristodoulou, Dimitrios Hatzichristou, Francois Giuliano
INTRODUCTION: Despite recent promising clinical results, the underlying mechanism of action of low-intensity extracorporeal shockwave therapy (Li-ESWT) for erectile dysfunction (ED) is mostly unclear and currently under investigation. AIM: To systematically identify and evaluate evidence regarding the basic science behind Li-ESWT for ED, discuss and propose a putative mechanism of action, address the limitations, and imply insights for further investigation in the field...
February 2019: Journal of Sexual Medicine
#40
JOURNAL ARTICLE
Piper Nicolosi, Elisa Ledet, Shan Yang, Scott Michalski, Brandy Freschi, Erin O'Leary, Edward D Esplin, Robert L Nussbaum, Oliver Sartor
Importance: Prostate cancer is the third leading cause of cancer-related death in men in the United States. Although serious, most of these diagnoses are not terminal. Inherited risk for prostate cancer is associated with aggressive disease and poorer outcomes, indicating a critical need for increased genetic screening to identify disease-causing variants that can pinpoint individuals at increased risk for metastatic castration-resistant prostate cancer. Objective: To identify positive (pathogenic, likely pathogenic, and increased risk) germline variants in a large prostate cancer cohort and to evaluate the usefulness of current practice guidelines in recognizing individuals at increased risk for prostate cancer who would benefit from diagnostic genetic testing...
April 1, 2019: JAMA Oncology
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