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Essential Urology

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294 papers 500 to 1000 followers Just essential articles for your daily practice.
By Axel Cayetano Urologist
Jeffrey J Leow, Jens Bedke, Karim Chamie, Justin W Collins, Siamak Daneshmand, Petros Grivas, Axel Heidenreich, Edward M Messing, Trevor J Royce, Alexander I Sankin, Mark P Schoenberg, William U Shipley, Arnauld Villers, Jason A Efstathiou, Joaquim Bellmunt, Arnulf Stenzl
PURPOSE: To provide a comprehensive overview and update of the Joint Société Internationale d'Urologie-International Consultation on Urological Diseases (SIU-ICUD) Consultation on Bladder Cancer for muscle-invasive presumably node-negative bladder cancer (MIBC). METHODS: Contemporary literature was analyzed for the latest evidence in treatment options, outcomes, including radical surgery, neoadjuvant and adjuvant treatment modalities, and bladder-sparing approaches...
January 2019: World Journal of Urology
Olivier Traxer, Etienne Xavier Keller
PURPOSE: To compare the operating modes of the Holmium:YAG laser and Thulium fiber laser. Additionally, currently available literature on Thulium fiber laser lithotripsy is reviewed. MATERIALS AND METHODS: Medline, Scopus, Embase, and Web of Science databases were searched for articles relating to the operating modes of Holmium:YAG and Thulium fiber lasers, including systematic review of articles on Thulium fiber laser lithotripsy. RESULTS: The laser beam emerging from the Holmium:YAG laser involves fundamental architectural design constraints compared to the Thulium fiber laser...
February 6, 2019: World Journal of Urology
Osamah Al-Bayati, Aws Hasan, Deepak Pruthi, Dharam Kaushik, Michael A Liss
To perform a systematic review of modifiable risk factors associated with the incidence of renal cell cancer (RCC). A systematic search of the literature was conducted using PubMed, Cochrane, and Web of Science databases from January 1996 until August 2017. We also extracted articles from the reference lists of identified studies and reviews. We targeted modifiable risk factors for RCC to include exercise, smoking, alcohol, diet, obesity, hypertension, and diabetes. We utilized predefined inclusion criteria and the Preferred Reporting Items for Systematic Reviews and Meta-analysis statement...
January 24, 2019: Urologic Oncology
Takehiro Iwata, Shoji Kimura, Beat Foerster, Mohammad Abufaraj, Pierre I Karakiewicz, Felix Preisser, Yasutomo Nasu, Shahrokh F Shariat
AIM: To investigate the association of perioperative blood transfusion (PBT) with oncologic outcomes in patients with renal cell carcinoma (RCC), we conducted a systematic review and meta-analysis of the literature to clarify the long-term oncologic effect of PBT in patients undergoing nephrectomy for RCC. MATERIALS AND METHODS: We searched the MEDLINE, Web of Science, Cochrane Library and Scopus on 15th April 2018 to identify studies that compared patients who received PBT undergoing radical or partial nephrectomy for RCC to patients who did not with the aim of evaluating its impact on overall mortality (OM), cancer-specific mortality (CSM) and disease recurrence using multivariable cox regression analysis...
February 5, 2019: Urologic Oncology
Luiz S Guedes-Barbosa
A 31-year-old man presented to an outpatient clinic with a 5-day history of oral and genital ulcers. He had a 2-year history of recurrent oral and genital lesions, and 6 months before presentation, erythema nodosum had developed on his legs. Tests for herpes simplex virus and syphilis were..
February 7, 2019: New England Journal of Medicine
Tomohiro Matsuo, Yasuyoshi Miyata, Hideki Sakai
AIMS: To assess the efficacy of salt reduction for improving nocturia in patients with high salt intake. METHODS: Changes in lower urinary symptoms and frequency volume chart by salt intake (men: 8 g/day; women: ≥7 g/day) were analyzed in this prospective study. Patients were instructed to use a brochure for salt intake restriction via interview once every four weeks. The daily salt intake was estimated by using spot urine samples. RESULTS: Two-hundred twenty-three (69...
February 1, 2019: Neurourology and Urodynamics
Mario Preti, Pedro Vieira-Baptista, Giuseppe Alessandro Digesu, Carol Emi Bretschneider, Margot Damaser, Oktay Demirkesen, Debra S Heller, Naside Mangir, Claudia Marchitelli, Sherif Mourad, Micheline Moyal-Barracco, Sol Peremateu, Visha Tailor, Tufan Tarcan, Elise J B De, Colleen K Stockdale
BACKGROUND: The clinical role of LASER for vulvar and vaginal treatments in gynecology and female urology is controversial. AIMS: In this best practice document, we propose recommendations for the use of LASER for gynecologic and urologic conditions such as vulvovaginal atrophy, urinary incontinence, vulvodynia, and lichen sclerosus based on a thorough literature review. MATERIALS & METHODS: This project was developed between January and September 2018...
February 11, 2019: Neurourology and Urodynamics
Bertrand Tombal, Fred Saad, David Penson, Maha Hussain, Cora N Sternberg, Robert Morlock, Krishnan Ramaswamy, Cristina Ivanescu, Gerhardt Attard
BACKGROUND: In the PROSPER trial, enzalutamide significantly improved metastasis-free survival in patients with non-metastatic, castration-resistant prostate cancer. Here, we report the results of patient-reported outcomes of this study. METHODS: In the randomised, double-blind, placebo-controlled, phase 3 PROSPER trial, done at 254 study sites worldwide, patients aged 18 years or older with non-metastatic, castration-resistant prostate cancer and a prostate-specific antigen doubling time of up to 10 months were randomly assigned (2:1) via an interactive voice web recognition system to receive oral enzalutamide (160 mg per day) or placebo...
February 12, 2019: Lancet Oncology
Ioannis Sokolakis, Fotios Dimitriadis, Pearline Teo, Georgios Hatzichristodoulou, Dimitrios Hatzichristou, Francois Giuliano
INTRODUCTION: Despite recent promising clinical results, the underlying mechanism of action of low-intensity extracorporeal shockwave therapy (Li-ESWT) for erectile dysfunction (ED) is mostly unclear and currently under investigation. AIM: To systematically identify and evaluate evidence regarding the basic science behind Li-ESWT for ED, discuss and propose a putative mechanism of action, address the limitations, and imply insights for further investigation in the field...
February 2019: Journal of Sexual Medicine
Piper Nicolosi, Elisa Ledet, Shan Yang, Scott Michalski, Brandy Freschi, Erin O'Leary, Edward D Esplin, Robert L Nussbaum, Oliver Sartor
Importance: Prostate cancer is the third leading cause of cancer-related death in men in the United States. Although serious, most of these diagnoses are not terminal. Inherited risk for prostate cancer is associated with aggressive disease and poorer outcomes, indicating a critical need for increased genetic screening to identify disease-causing variants that can pinpoint individuals at increased risk for metastatic castration-resistant prostate cancer. Objective: To identify positive (pathogenic, likely pathogenic, and increased risk) germline variants in a large prostate cancer cohort and to evaluate the usefulness of current practice guidelines in recognizing individuals at increased risk for prostate cancer who would benefit from diagnostic genetic testing...
February 7, 2019: JAMA Oncology
Melanie R Hassler, Shahrokh F Shariat, Francesco Soria
PURPOSE OF REVIEW: To give an overview of current options for conservative treatment of patients failing intravesical bacillus Calmette-Guerin (BCG) and to discuss emerging approaches with potential future clinical applications. RECENT FINDINGS: Radical cystectomy is the standard-of-care for patients failing BCG therapy. In patients unfit or unwilling to undergo surgery, salvage therapy options could be proposed with the aim to offer local cancer control and prevent progression to muscle-invasive disease...
February 11, 2019: Current Opinion in Urology
J Kam, Y Yuminaga, M Krelle, D Gavin, S Koschel, K Aluwihare, T Sutherland, S Skinner, J Brennan, L M Wong, M Louie-Johnsun
OBJECTIVES: To assess the accuracy of multi-parametric MRI (mpMRI) for the detection of significant prostate cancer in men undergoing radical prostatectomy (RP) in an Australian multi-centre setting. Secondary aims were to assess concordance between mpMRI and RP for local tumour staging and index lesion locations. PATIENTS AND METHODS: Patients who had an mpMRI performed within 12 months of RP between January 2013 and August 2016 at 3 Australian Sites were included (Central Coast, NSW, St Vincents Hospital, Melbourne, VIC, and Bendigo Hospital, VIC)...
February 3, 2019: BJU International
Allison S Glass, Marc A Dall'Era
OBJECTIVES: To review the role of multi-parametric magnetic resonance imaging (mpMRI) for active surveillance of prostate cancer. MATERIALS AND METHODS: We performed a comprehensive search of Medline and Embase databases for relevant articles. Search terms included prostate cancer, active surveillance or monitoring, expectant management, and MRI in the English language. We also reviewed practice guidelines from recognized international associations or societies involved in prostate cancer care...
February 11, 2019: BJU International
Samuel W D Merriel, Liz Hetherington, Andrew Seggie, Joanna T Castle, William Cross, Monique J Roobol, Vincent Gnanapragasam, Caroline M Moore
OBJECTIVES: To develop a consensus statement on current best practice of active surveillance (AS) in the UK, informed by patients and clinical experts. SUBJECTS AND METHODS: A consensus statement was drafted on the basis of three sources of data: systematic literature search of national and international guidelines; data arising from a Freedom of Information (FOI) Act request to UK urology departments regarding their current practice of AS; survey and interview responses from men with localised prostate cancer regarding their experiences and views of AS...
February 11, 2019: BJU International
Mark C Markowski, Stephen A Boorjian, Jeremy P Burton, Noah M Hahn, Molly A Ingersoll, Saman Maleki Vareki, Sumanta K Pal, Karen S Sfanos
CONTEXT: The recent discovery of the existence of a human genitourinary microbiome has led to the investigation of its role in mediating the pathogenesis of genitourinary malignancies, including bladder, kidney, and prostate cancers. Furthermore, although it is largely recognized that members of the gastrointestinal microbiota are actively involved in drug metabolism, new studies demonstrate additional roles and the potential necessity of the gastrointestinal microbiota in dictating cancer treatment response...
January 14, 2019: European Urology
(no author information available yet)
No abstract text is available yet for this article.
February 2019: BJU International
Gagan Fervaha, Jason P Izard, Dean A Tripp, Selina Rajan, Darryl P Leong, D Robert Siemens
Prostate cancer is the most common malignancy among men. Given its prevalence and relatively low mortality rates, several biopsychosocial survivorship issues have garnered recent attention. This article reviews the literature on the association between depression and prostate cancer, emphasizing key practice points relevant for clinicians. Depression is prevalent among men with prostate cancer, with approximately 1 in 6 patients experiencing clinical depression. Suicidal ideation is also not uncommon in this population and does not always present in those with other depressive symptoms...
January 7, 2019: Urologic Oncology
Jeffrey Rogers, Alan C Farney, Giuseppe Orlando, David Harriman, Amber Reeves-Daniel, Colleen L Jay, William Doares, Scott Kaczmorski, Michael D Gautreaux, Robert J Stratta
BACKGROUND: The study purpose was to analyze outcomes in recipients of pediatric dual en bloc (PEB) kidneys from small pediatric donors (SPDs, age ≤ 3 years) and dual kidney transplants (KTs) from adult marginal deceased donors (DDs) in the context of the Kidney Donor Profile Index (KDPI). STUDY DESIGN: This was a single center retrospective review. Recipient selection included primary transplant, low BMI, low immunologic risk, and informed consent. All patients received antibody induction with FK/MPA/± prednisone...
January 8, 2019: Journal of the American College of Surgeons
Chaoyue Lu, Wei Zhang, Yonghan Peng, Ling Li, Xiaomin Gao, Min Liu, Ziyu Fang, Zeyu Wang, Shaoxiong Ming, Hao Dong, Rong Shen, Fei Xie, Yinghao Sun, Xiaofeng Gao
BACKGROUND AND PURPOSE: Although balloon dilatation is one of the main endoscopic procedures used to treat benign ureteral strictures, its precise efficacy remains controversial. We aimed to identify, combine, and analyze existing published data to ascertain the efficacy of endoscopic balloon dilatation for benign ureteral strictures. METHODS: In December 2018, a literature search was performed using Medline, Embase, and Web of Science databases. We included reports in which the study population consisted of patients who underwent endoscopic balloon dilatation for the treatment of benign ureteral strictures...
January 10, 2019: Journal of Endourology
Muhammad Imran Omar, Raj Prasenjit Pal, Brian D Kelly, Harman Maxim Bruins, Yuhong Yuan, Thorsten Diemer, Csilla Krausz, Herman Tournaye, Zsolt Kopa, Andreas Jungwirth, Suks Minhas
CONTEXT: Empiric use of medical and nutritional supplements to improve semen parameters and pregnancy rates in couples with idiopathic infertility has reached global proportions, although the evidence base for their use in this setting is controversial. OBJECTIVE: We systematically reviewed evidence comparing the benefits of nutritional and medical therapy on pregnancy rates and semen parameters in men with idiopathic infertility. EVIDENCE ACQUISITION: A literature search was performed using MEDLINE, Embase, LILACS, and the Cochrane Library (searched from January 1, 1990 to September 19, 2017)...
January 7, 2019: European Urology
2019-01-17 04:07:50
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