Emanuela Palmerini, Eric L Staals, Robert G Maki, Stefano Pengo, Angela Cioffi, Marco Gambarotti, Piero Picci, Primo Andrea Daolio, Antonina Parafioriti, Carol Morris, Cristina R Antonescu, Alessandro Gronchi, Paolo Giovanni Casali, Davide M Donati, Stefano Ferrari, Silvia Stacchiotti
BACKGROUND: Tenosynovial giant cell tumour/pigmented villonodular synovitis (TGCT/PVNS) is a benign neoplasm of synovium and tendon sheath. We conducted a retrospective pooled analysis in three major referral centers. METHODS: Patients treated between 1998 and 2008 were examined. Only patients presenting with primary disease or first relapse were included. 5-year local failure free survival (5-year-LFFS) was analysed. RESULTS: 294 patients were included: 254 with new diagnosis and 40 in 1st local recurrence (171 F/123 M; median age: 36 years; tumour size ⩽2 cm in 27% of patients, >2 to ⩽5 cm in 41%, and >5 cm in 32%)...
January 2015: European Journal of Cancer