Eduardo A Osawa, Andrew Rhodes, Giovanni Landoni, Filomena R B G Galas, Julia T Fukushima, Clarice H L Park, Juliano P Almeida, Rosana E Nakamura, Tania M V Strabelli, Brunna Pileggi, Alcino C Leme, Evgeny Fominskiy, Yasser Sakr, Marta Lima, Rafael A Franco, Raquel P C Chan, Marilde A Piccioni, Priscilla Mendes, Suéllen R Menezes, Tatiana Bruno, Fabio A Gaiotto, Luiz A Lisboa, Luiz A O Dallan, Alexandre C Hueb, Pablo M Pomerantzeff, Roberto Kalil Filho, Fabio B Jatene, Jose Otavio Costa Auler Junior, Ludhmila A Hajjar
OBJECTIVES: To evaluate the effects of goal-directed therapy on outcomes in high-risk patients undergoing cardiac surgery. DESIGN: A prospective randomized controlled trial and an updated metaanalysis of randomized trials published from inception up to May 1, 2015. SETTING: Surgical ICU within a tertiary referral university-affiliated teaching hospital. PATIENTS: One hundred twenty-six high-risk patients undergoing coronary artery bypass surgery or valve repair...
April 2016: Critical Care Medicine