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By Lazaro Garcia flores Neuroendocrino tumor
Sunandini Sridhar, Yair Botbol, Fernando Macian, Ana Maria Cuervo
Autophagy is a process traditionally known to contribute to cellular cleaning through the removal of intracellular components in lysosomes. In recent years, intensive scrutiny at the molecular level to which autophagy has been subjected has also contributed to expanding our understanding of the physiological role of this pathway. Added to the well-characterized role in quality control, autophagy has proved to be important in the maintenance of cellular homeostasis and of the energetic balance, in cellular and tissue remodelling, and cellular defence against extracellular insults and pathogens...
January 2012: Journal of Pathology
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