Yuan Ma, Feng J He, Qi Sun, Changzheng Yuan, Lyanne M Kieneker, Gary C Curhan, Graham A MacGregor, Stephan J L Bakker, Norm R C Campbell, Molin Wang, Eric B Rimm, JoAnn E Manson, Walter C Willett, Albert Hofman, Ron T Gansevoort, Nancy R Cook, Frank B Hu
BACKGROUND: The relation between sodium intake and cardiovascular disease remains controversial, owing in part to inaccurate assessment of sodium intake. Assessing 24-hour urinary excretion over a period of multiple days is considered to be an accurate method. METHODS: We included individual-participant data from six prospective cohorts of generally healthy adults; sodium and potassium excretion was assessed with the use of at least two 24-hour urine samples per participant...
January 20, 2022: New England Journal of Medicine