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Clare Marchand, Andrew R L Medford
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) diagnoses and stages mediastinal lymph node pathology. This retrospective study determined the relationship between EBUS-TBNA utility and non-small cell lung cancer (NSCLC) stage, lymph node size, and positron emission tomography (PET) standard uptake values (SUV), and the utility of neck ultrasound in bulky mediastinal disease. METHODS: Data of 284 consecutive patients who had undergone EBUS-TBNA was collected...
July 2017: Thoracic Cancer
Mehrdad Talebian Yazdi, Joost Egberts, Mink S Schinkelshoek, Ron Wolterbeek, Johannes Nabers, Ben J W Venmans, Kurt G Tournoy, Jouke T Annema
OBJECTIVES: Non-small cell lung cancer (NSCLC) guidelines recommend endosonography (endobronchial [EBUS] and/or transesophageal ultrasound [EUS]) as the initial step for mediastinal tissue staging. Identifying predictors for false negative results could help establish which patients should undergo confirmatory surgical staging. MATERIALS AND METHODS: 775 NSCLC patients staged negative by EBUS, EUS or combined EUS/EBUS were retrospectively analyzed. Predictors of false-negative outcomes were identified by logistic regression analysis...
December 2015: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
Matthew Evison, Julie Morris, Julie Martin, Rajesh Shah, Philip V Barber, Richard Booton, Philip A J Crosbie
BACKGROUND: Over the last 10 years, endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) has become established as the first-line nodal staging procedure of choice for lung cancer patients. However, the pathway for patients following a negative EBUS-TBNA has not been clearly defined. The primary aim of this study was to develop and validate a risk stratification model to categorize lymph nodes deemed negative by EBUS-TBNA into "low-risk" and "high-risk" groups, where "risk" refers to the risk of false negative sampling...
January 2015: Journal of Thoracic Oncology
Robert C Rintoul, Kurt G Tournoy, Hesham El Daly, Nicholas R Carroll, Robert C Buttery, Klaas van Kralingen, Jan P van Meerbeeck, Klaus F Rabe, Jouke T Annema
INTRODUCTION: To determine the sensitivity and accuracy of endobronchial ultrasound guided transbronchial needle aspiration (EBUS-TBNA) for clarification of the nature of fluorodeoxyglucose-positron emission tomography (FDG) positive hilar and/or mediastinal lymph nodes in patients with (suspected) lung cancer. METHODS: All consecutive patients who had undergone EBUS-TBNA alone for assessment of abnormal FDG-uptake in hilar and/or mediastinal lymph nodes between January 2005 and August 2007 were reviewed...
January 2009: Journal of Thoracic Oncology
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